The Inhibitory Effect of Adenylic Acid on the Bitterness of the Antibacterial Combination Drug Trimethoprim/Sulfamethoxazole

Autor: Jun Kawahara, Miyako Yoshida, Honami Kojima, Rio Uno, Minoru Ozeki, Ikuo Kawasaki, Masaaki Habara, Hidekazu Ikezaki, Takahiro Uchida

Publikováno v: Chemical and Pharmaceutical Bulletin. 71:198-205

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20c756e05b77e2f1296fd93ef984b6a1
https://doi.org/10.1248/cpb.c22-00618

Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms

Autor: Tamami Haraguchi, Miyako Yoshida, Honami Kojima, Takahiro Uchida

Publikováno v: Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 4, Pp 479-485 (2016)

The purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral dosage forms. First, we consider some ways in which the palatability of various pharmaceutical f

Externí odkaz: https://doaj.org/article/c0a4298b5a994532a65c564dea2b182d

Inhibitory Effect of 5-Adenylic Acid on Bitter Taste of Antipsychotic Drugs

Autor: Jun Kawahara, Rio Uno, Honami Kojima, Miyako Yoshida, Takahiro Uchida, Hidekazu Ikezaki, Masaaki Habara

Publikováno v: Pharmacology & Pharmacy. 13:429-446

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75e5b54d132374cc406974333d335181
https://doi.org/10.4236/pp.2022.1310032

Development of Taste Sensor to Detect Non-Charged Bitter Substances

Autor: Jumpei Yoshimatsu, Kiyoshi Toko, Yusuke Tahara, Misaki Ishida, Masaaki Habara, Hidekazu Ikezaki, Honami Kojima, Saeri Ikegami, Miyako Yoshida, Takahiro Uchida

Publikováno v: Sensors, Vol 20, Iss 12, p 3455 (2020)

A taste sensor with lipid/polymer membranes is one of the devices that can evaluate taste objectively. However, the conventional taste sensor cannot measure non-charged bitter substances, such as caffeine contained in coffee, because the taste sensor

Externí odkaz: https://doaj.org/article/fbf134c53e8f45ffbfcc4bfc10b51624

Targeted Delivery of Miconazole Employing LL37 Fragment Mutant Peptide CKR12-Poly (Lactic-Co-Glycolic) Acid Polymeric Micelles

Autor: Toshihiro Nagao, Takahiro Uchida, Daisuke Ishibashi, Rie Kakehashi, Miki Yoshii, Mai Hazekawa, Yoshiro Hatanaka, Makoto Nakagawa, Takeshi Mori, Honami Kojima, Miyako Yoshida, Rio Uno

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12056, p 12056 (2021)
Volume 22
Issue 21

We previously reported that conjugates of antimicrobial peptide fragment analogues and poly (lactic-co-glycolic) acid (PLGA) enhance antimicrobial activity and that the conjugated micelle structure is an effective tool for antimicrobial drug delivery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22df2ef713e70e5edc68c473dc3222a5
https://pubmed.ncbi.nlm.nih.gov/34769486