Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.

Autor: Rangel R; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030., Lee SC; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673., Hon-Kim Ban K; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673.; Deparment of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 138673., Guzman-Rojas L; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030., Mann MB; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030., Newberg JY; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030., Kodama T; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030., McNoe LA; Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Selvanesan L; Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Ward JM; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673., Rust AG; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1HH, United Kingdom., Chin KY; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673., Black MA; Department of Biochemistry, University of Otago, Dunedin 9016, New Zealand., Jenkins NA; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030.; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673., Copeland NG; Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030; ncopeland@houstonmethodist.org.; Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore 138673.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Nov 29; Vol. 113 (48), pp. E7749-E7758. Date of Electronic Publication: 2016 Nov 14.