Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Hon-Fai Chan"'
Autor:
Xiaobo Zhu, Mingde Cao, Kejia Li, Yau-Tsz Chan, Hon-Fai Chan, Yi-Wah Mak, Hao Yao, Jing Sun, Michael Tim-Yun Ong, Kevin Ki-Wai Ho, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Patrick Shu-Hang Yung, Yangzi Jiang
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 255-272 (2024)
Osteoarthritis (OA) is a major clinical challenge, and effective disease-modifying drugs for OA are still lacking due to the complicated pathology and scattered treatment targets. Effective early treatments are urgently needed to prevent OA progressi
Externí odkaz:
https://doaj.org/article/65efe12f07f7452db3d7098879962681
Autor:
Christy Wing Tung Wong, Apurva Sawhney, Yalan Wu, Yi Wah Mak, Xiao Yu Tian, Hon Fai Chan, Anna Blocki
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Critical limb ischemia (CLI) is the most severe form of peripheral artery disease and exhibits a high risk of lower extremity amputations. As even the most promising experimental approaches based on mesenchymal stem cells (MSCs) d
Externí odkaz:
https://doaj.org/article/2825c3d3b00a438787ac47fc55e74966
Autor:
Yuqin Liang, Xihao Sun, Chunwen Duan, Yalan Zhou, Zekai Cui, Chengcheng Ding, Jianing Gu, Shengru Mao, Shangli Ji, Hon Fai Chan, Shibo Tang, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102911- (2022)
Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases characterized by nyctalopia, progressive vision loss and visual field contraction. we previously generated an induced pluripotent stem cell line (CSUASOi004-A) from a RP p
Externí odkaz:
https://doaj.org/article/3c527ec78b69480e8d81d1f9f11f43e8
Autor:
Ting Su, Liying Liang, Lan Zhang, Jianing Wang, Luyin Chen, Caiying Su, Jixing Cao, Quan Yu, Shuai Deng, Hon Fai Chan, Shibo Tang, Yonglong Guo, Jiansu Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Retinitis pigmentosa (RP) is a leading cause of vision impairment and blindness worldwide, with limited medical treatment options. USH2A mutations are one of the most common causes of non-syndromic RP. In this study, we developed retinal organoids (R
Externí odkaz:
https://doaj.org/article/48118f4b207649a0aa8ef21185b5bed1
Autor:
Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li
Publikováno v:
Bioactive Materials. 28:112-131
Autor:
Liying Liang, Yunxia Xue, Caiying Su, Jianing Wang, Luyin Chen, Ting Su, Jianyu Ke, Linyao Xie, Zekai Cui, Quan Yu, Hon fai Chan, Jingxiang Zhong, Yonglong Guo, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102699- (2022)
USH type 2 (USH2) is an autosomal recessive disorder that is characterized by inherited retinopathies and sensorineural hearing loss. USH type 2 (USH2) is frequently caused by USH2A mutations, which account for 74–90% of USH2 cases. We used periphe
Externí odkaz:
https://doaj.org/article/7343b4364b1041809eb3a0933de3a4f1
Autor:
Yuqin Liang, Feng Tan, Xihao Sun, Zekai Cui, Jianing Gu, Shengru Mao, Hon Fai Chan, Shibo Tang, Jiansu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9049 (2022)
Pre-mRNA processing factors (PRPFs) are vital components of the spliceosome and are involved in the physiological process necessary for pre-mRNA splicing to mature mRNA. As an important member, PRPF6 mutation resulting in autosomal dominant retinitis
Externí odkaz:
https://doaj.org/article/68436090a22f4d15876f353f3673d934
Autor:
Xinyue Liu, Christoph Steiger, Shaoting Lin, German Alberto Parada, Ji Liu, Hon Fai Chan, Hyunwoo Yuk, Nhi V. Phan, Joy Collins, Siddartha Tamang, Giovanni Traverso, Xuanhe Zhao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
High swelling ratio, speed and long term robustness tend not coexist in hydrogels which limits their use in devices. Here, the authors introduce a pufferfish-inspired hydrogel device ingested as a standard-sized pill, swells rapidly and maintains rob
Externí odkaz:
https://doaj.org/article/85523130a21c4cd6ba89dc379e25b344
Autor:
Wentao Dang, Yuqin Wang, Wei-Chih Chen, Enguo Ju, Rachel L. Mintz, Yue Teng, Lili Zhu, Kun Wang, Shixian Lv, Hon Fai Chan, Yu Tao, Mingqiang Li
Publikováno v:
ACS Applied Materials & Interfaces. 15:4911-4923
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
Liver failure is a lethal condition with hepatocellular dysfunction, and liver transplantation is presently the only effective treatment. However, due to the limited availability of donors and the potential immune rejection, novel therapeutic strateg
Externí odkaz:
https://doaj.org/article/f0eab3ba8ad746c8800b97e23af63a01