Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hon Lyn Tan"'
Autor:
Joan Choo, Ley Fang Kua, Mu Yar Soe, Bernadette Reyna Asuncion, Benjamin Kye Jyn Tan, Chong Boon Teo, Ryan Yong Kiat Tay, Jimmy So, Asim Shabbir, Kim Guowei, Hon Lyn Tan, Gloria Chan, Haoran Ma, Gokula Krishnan Ramachandran, Jeffrey H. Y. Lum, Cheng Ean Chee, Sriram Sridharan, Patrick Tan, Raghav Sundar, Wei Peng Yong
Publikováno v:
Gastric Cancer. 26:393-404
Background We evaluated the relevance of PD-1+CD8+ T-cells in gastric cancer (GC) including prognostic significance, association with chemotherapy and immunotherapy sensitivity and correlations with the tumor microenvironment (TME). Methods Discovery
Autor:
Dario Campana, Boon Cher Goh, Priscillia J.X. Koe, Jedidah L.M. Lieow, Nesaretnam Barr Kumarakulasinghe, Wan Qin Chong, Hon Lyn Tan, Raghav Sundar, Elaine Coustan-Smith, Mabel Z.Q. Foo, Yoon Sim Yap, Lavina Bharwani, Samuel G.W. Ow, Sing Huang Tan, Michelle L.M. Poon, Liang Piu Koh, Lip Kun Tan, Wei Peng Yong, Kritika Yadav, Andrea Wong, Joline S.J. Lim, Noriko Shimasaki, Soo-Chin Lee
Purpose:Natural killer (NK) cells exert antibody-dependent cell cytotoxicity (ADCC). We infused expanded, activated autologous NK cells to potentiate trastuzumab-mediated ADCC in patients with HER2-positive malignancies.Patients and Methods:In a phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaab96d906f2da5fd2a148efdea4c8ed
https://doi.org/10.1158/1078-0432.c.6529842
https://doi.org/10.1158/1078-0432.c.6529842
Autor:
Jimmy B.Y. So, Lingzhi Wang, Wei Peng Yong, Boon Cher Goh, Wee Han Ang, Maria V. Babak, Asim Shabbir, Jingshan Ho, Cheng Ean Chee, Bettina Lieske, Raghav Sundar, Hon Lyn Tan, Guowei Kim
Purpose:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel laparoscopic, intraperitoneal chemotherapy delivery technique aiming to improve drug distribution and tissue penetration to treat peritoneal metastases. Thus far, PIPAC oxali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93375eda413b7ef3ec44ff4c80fe8bf8
https://doi.org/10.1158/1078-0432.c.6531359.v1
https://doi.org/10.1158/1078-0432.c.6531359.v1
Autor:
Jimmy B.Y. So, Lingzhi Wang, Wei Peng Yong, Boon Cher Goh, Wee Han Ang, Maria V. Babak, Asim Shabbir, Jingshan Ho, Cheng Ean Chee, Bettina Lieske, Raghav Sundar, Hon Lyn Tan, Guowei Kim
Mean concentration-time profiles of pressurized intraperitoneal aerosol chemotherapy (PIPAC) oxaliplatin (n = 14) in plasmatot (A) and ultrafiltrate (B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5c2d5baeb70f6b28c45d6a57d27cf8
https://doi.org/10.1158/1078-0432.22484231
https://doi.org/10.1158/1078-0432.22484231
Autor:
Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim
Purpose:RET is an estrogen response gene with preclinical studies demonstrating cross-talk between the RET and estrogen receptor (ER) pathways. We investigate the role of lenvatinib, a multikinase inhibitor with potent activity against RET, in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e493f677e970d70092bf8afa81bf17c
https://doi.org/10.1158/1078-0432.c.6532424.v1
https://doi.org/10.1158/1078-0432.c.6532424.v1
Autor:
Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim
Supplementary Table from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02061fae97a0b8e77fb74d487409f1d
https://doi.org/10.1158/1078-0432.22486937
https://doi.org/10.1158/1078-0432.22486937
Autor:
Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim
Supplementary Data from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00fc277da44ab4288b38054c7a7e0c6
https://doi.org/10.1158/1078-0432.22486946
https://doi.org/10.1158/1078-0432.22486946
Autor:
Soo-Chin Lee, Boon Cher Goh, Bee Choo Tai, Lingzhi Wang, Supriya Jain, Kritika Yadav, Raghav Sundar, Cheng Ean Chee, David S.P. Tan, Ross A. Soo, Wei Peng Yong, Hon Lyn Tan, Joan R.E. Choo, Matilda Lee, Yi Wan Lim, Siew Eng Lim, Wan Qin Chong, Yvonne L.E. Ang, Gloria H.J. Chan, Natalie Y.L. Ngoi, Samuel G.W. Ow, Andrea L.A. Wong, Joline S.J. Lim
Supplementary Figure from Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor–Positive Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51301d328c110373e6f3c2828ea93958
https://doi.org/10.1158/1078-0432.22486943
https://doi.org/10.1158/1078-0432.22486943
Autor:
Jimmy B.Y. So, Lingzhi Wang, Wei Peng Yong, Boon Cher Goh, Wee Han Ang, Maria V. Babak, Asim Shabbir, Jingshan Ho, Cheng Ean Chee, Bettina Lieske, Raghav Sundar, Hon Lyn Tan, Guowei Kim
The area under the curve(AUC) ratio (Ultrafiltrate(UF) vs Plasmatot) at different dose levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107d5e304676777a972386cc3f62b445
https://doi.org/10.1158/1078-0432.22484228
https://doi.org/10.1158/1078-0432.22484228
Autor:
Dario Campana, Boon Cher Goh, Priscillia J.X. Koe, Jedidah L.M. Lieow, Nesaretnam Barr Kumarakulasinghe, Wan Qin Chong, Hon Lyn Tan, Raghav Sundar, Elaine Coustan-Smith, Mabel Z.Q. Foo, Yoon Sim Yap, Lavina Bharwani, Samuel G.W. Ow, Sing Huang Tan, Michelle L.M. Poon, Liang Piu Koh, Lip Kun Tan, Wei Peng Yong, Kritika Yadav, Andrea Wong, Joline S.J. Lim, Noriko Shimasaki, Soo-Chin Lee
Supplementary Materials, Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0209f96b4c5f79fd3d29bd1e4c30823
https://doi.org/10.1158/1078-0432.22478064
https://doi.org/10.1158/1078-0432.22478064