Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Hon Fai Chan"'
Autor:
Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 112-131 (2023)
Reactive oxygen species (ROS)-associated oxidative stress, inflammation storm, and massive hepatocyte necrosis are the typical manifestations of acute liver failure (ALF), therefore specific therapeutic interventions are essential for the devastating
Externí odkaz:
https://doaj.org/article/9d76953081d14a12a517610f55416961
Autor:
Christy Wing Tung Wong, Apurva Sawhney, Yalan Wu, Yi Wah Mak, Xiao Yu Tian, Hon Fai Chan, Anna Blocki
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Critical limb ischemia (CLI) is the most severe form of peripheral artery disease and exhibits a high risk of lower extremity amputations. As even the most promising experimental approaches based on mesenchymal stem cells (MSCs) d
Externí odkaz:
https://doaj.org/article/2825c3d3b00a438787ac47fc55e74966
Autor:
Yanlun Zhu, Yiwei Wang, Guanggai Xia, Xuerao Zhang, Shuai Deng, Xiaoyu Zhao, Yanteng Xu, Guozhu Chang, Yu Tao, Mingqiang Li, Haiyan Li, Xinyu Huang, Hon Fai Chan
Publikováno v:
Advanced Science, Vol 10, Iss 18, Pp n/a-n/a (2023)
Abstract Resolving inflammation and promoting intestinal tissue regeneration are critical for inflammatory bowel disease (IBD) treatment. Bioactive glass (BG) is a clinically approved bone graft material and has been shown to modulate inflammatory re
Externí odkaz:
https://doaj.org/article/019bdd0179df41d390afae2f7ba8a9bb
Autor:
Luyin Chen, Jianing Wang, Tingting Yang, Linyao Xie, Zekai Cui, Quan Yu, Jingxiang Zhong, Hon fai Chan, Yunxia Xue, Yonglong Guo, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 68, Iss , Pp 103055- (2023)
We generated an induced pluripotent stem (iPS) cell line by reprogramming peripheral blood mononuclear cells of a patient with Usher syndrome type II carrying USH2A gene mutation (c.8559-2A > G). The iPS cell line with confirmed patient-specific poin
Externí odkaz:
https://doaj.org/article/92e862083d8e4877b8f08e38fb3958da
Autor:
Yixin Zhang, Yanteng Xu, Huimin Kong, Jiabin Zhang, Hon Fai Chan, Jiasi Wang, Dan Shao, Yu Tao, Mingqiang Li
Publikováno v:
Exploration, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Global increasing demand for high life quality and length facilitates the development of tissue engineering and regenerative medicine, which apply multidisciplinary theories and techniques to achieve the structural reconstruction and functio
Externí odkaz:
https://doaj.org/article/8048a68c24a84daf934a89504a1a07f5
Autor:
Hongtao Xu, Yanlun Zhu, Jiankun Xu, Wenxue Tong, Shiwen Hu, Yi‐Fan Chen, Shuai Deng, Hao Yao, Jie Li, Chien‐Wei Lee, Hon Fai Chan
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Tendon healing is a complex process involving inflammation, proliferation, and remodeling, eventually achieving a state of hypocellularity and hypovascularity. Currently, few treatments can satisfactorily restore the structure and function o
Externí odkaz:
https://doaj.org/article/81f7e16591e7417596f227dc511403b3
Autor:
Yuqin Liang, Xihao Sun, Chunwen Duan, Yalan Zhou, Zekai Cui, Chengcheng Ding, Jianing Gu, Shengru Mao, Shangli Ji, Hon Fai Chan, Shibo Tang, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102911- (2022)
Retinitis pigmentosa (RP) is one of the most common inherited retinal diseases characterized by nyctalopia, progressive vision loss and visual field contraction. we previously generated an induced pluripotent stem cell line (CSUASOi004-A) from a RP p
Externí odkaz:
https://doaj.org/article/3c527ec78b69480e8d81d1f9f11f43e8
Autor:
Ting Su, Liying Liang, Lan Zhang, Jianing Wang, Luyin Chen, Caiying Su, Jixing Cao, Quan Yu, Shuai Deng, Hon Fai Chan, Shibo Tang, Yonglong Guo, Jiansu Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Retinitis pigmentosa (RP) is a leading cause of vision impairment and blindness worldwide, with limited medical treatment options. USH2A mutations are one of the most common causes of non-syndromic RP. In this study, we developed retinal organoids (R
Externí odkaz:
https://doaj.org/article/48118f4b207649a0aa8ef21185b5bed1
Autor:
Liying Liang, Yunxia Xue, Caiying Su, Jianing Wang, Luyin Chen, Ting Su, Jianyu Ke, Linyao Xie, Zekai Cui, Quan Yu, Hon fai Chan, Jingxiang Zhong, Yonglong Guo, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102699- (2022)
USH type 2 (USH2) is an autosomal recessive disorder that is characterized by inherited retinopathies and sensorineural hearing loss. USH type 2 (USH2) is frequently caused by USH2A mutations, which account for 74–90% of USH2 cases. We used periphe
Externí odkaz:
https://doaj.org/article/7343b4364b1041809eb3a0933de3a4f1
Autor:
Yuqin Liang, Feng Tan, Xihao Sun, Zekai Cui, Jianing Gu, Shengru Mao, Hon Fai Chan, Shibo Tang, Jiansu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9049 (2022)
Pre-mRNA processing factors (PRPFs) are vital components of the spliceosome and are involved in the physiological process necessary for pre-mRNA splicing to mature mRNA. As an important member, PRPF6 mutation resulting in autosomal dominant retinitis
Externí odkaz:
https://doaj.org/article/68436090a22f4d15876f353f3673d934