Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Homsher MF"'
Autor:
Skudlarek JW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Cooke AJ; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Mitchell HJ; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Babaoglu K; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Shaw AW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Tong L; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Nomland AB; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Labroli M; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Sha D; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Mulhearn JJ; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Wu C; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Li SW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Beshore DC; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Hughes JME; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Jouffroy M; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Wang H; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Balibar CJ; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Painter RE; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Shen P; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Lange HS; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Ishchenko A; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Chen YT; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Klein DJ; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Tracy RW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Miller RR; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Cabalu TD; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Wu Z; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Leithead A; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Scapin G; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Hruza AW; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Dzhekieva L; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Bukhtiyarova M; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Homsher MF; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Xu M; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Bahnck-Teets C; Merck & Co., Inc., Rahway, New Jersey 07065, United States., McKenney D; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Buevich AV; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Liu J; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Zhang LK; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Meng T; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Kelly T; Merck & Co., Inc., Rahway, New Jersey 07065, United States., DiNunzio E; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Soisson S; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Cheng RKY; leadXpro AG, CH-5234 Villigen, Switzerland., Hennig M; leadXpro AG, CH-5234 Villigen, Switzerland., Raheem I; Merck & Co., Inc., Rahway, New Jersey 07065, United States., Walker SS; Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Sep 12; Vol. 67 (17), pp. 15620-15675. Date of Electronic Publication: 2024 Aug 22.
A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier.
Autor:
Hart EM; Department of Molecular Biology, Princeton University, Princeton, NJ 08540., Mitchell AM; Department of Molecular Biology, Princeton University, Princeton, NJ 08540., Konovalova A; Department of Molecular Biology, Princeton University, Princeton, NJ 08540.; Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030., Grabowicz M; Department of Molecular Biology, Princeton University, Princeton, NJ 08540.; Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, GA 30322.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322.; Division of Infectious Disease, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322., Sheng J; Department of Molecular Biology, Princeton University, Princeton, NJ 08540., Han X; Chemical Biology, Merck & Co., Inc., Kenilworth, NJ 07033., Rodriguez-Rivera FP; Chemical Biology, Merck & Co., Inc., Kenilworth, NJ 07033., Schwaid AG; Chemistry, Merck & Co., Inc., Boston, MA 02115., Malinverni JC; Infectious Disease, Merck & Co., Inc., West Point, PA 19486., Balibar CJ; Infectious Disease, Merck & Co., Inc., West Point, PA 19486., Bodea S; Chemistry, Merck & Co., Inc., Boston, MA 02115., Si Q; Pharmacology, Merck & Co., Inc., West Point, PA 19486., Wang H; Infectious Disease, Merck & Co., Inc., West Point, PA 19486., Homsher MF; Biologics and Vaccine Analytics, Merck & Co., Inc., West Point, PA 19486., Painter RE; Pharmacology, Merck & Co., Inc., West Point, PA 19486., Ogawa AK; Chemistry, Merck & Co., Inc., South San Francisco, CA 94080., Sutterlin H; Biology, Prokaryotics, Inc., Union, NJ 07083., Roemer T; Biology, Prokaryotics, Inc., Union, NJ 07083., Black TA; Infectious Disease, Merck & Co., Inc., West Point, PA 19486., Rothman DM; Chemical Biology, Merck & Co., Inc., Kenilworth, NJ 07033., Walker SS; Infectious Disease, Merck & Co., Inc., West Point, PA 19486., Silhavy TJ; Department of Molecular Biology, Princeton University, Princeton, NJ 08540; tsilhavy@princeton.edu.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Oct 22; Vol. 116 (43), pp. 21748-21757. Date of Electronic Publication: 2019 Oct 07.
Autor:
Nothstein J; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA., MacColl E; 2 Hamilton College, Clinton, NY, USA., Zuck P; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA., Cassaday J; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA., Uebele VN; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA., Hermes JD; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA., Homsher MF; 1 Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA, USA.
Publikováno v:
SLAS technology [SLAS Technol] 2017 Oct; Vol. 22 (5), pp. 485-492. Date of Electronic Publication: 2016 Dec 27.
Autor:
Pertusi DA; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA., O'Donnell G; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Homsher MF; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Solly K; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Patel A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Stahler SL; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Riley D; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Finley MF; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA., Finger EN; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 5 Discovery & Preclinical Development, GlaxoSmithKline, Collegeville, PA, USA., Adam GC; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Meng J; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Bell DJ; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., Zuck PD; 6 Merck & Co., Inc., North Wales, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Hudak EM; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., Weber MJ; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Nothstein JE; 3 Merck & Co., Inc., West Point, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Locco L; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Quinn C; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Amoss A; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Squadroni B; 3 Merck & Co., Inc., West Point, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Hartnett M; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Heo MR; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., White T; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., May SA; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Boots E; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Roberts K; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Cocchiarella P; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., Wolicki A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Kreamer A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 9 Merck & Co., Inc., Kenilworth, NJ, USA., Kutchukian PS; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Wassermann AM; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Uebele VN; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., Glick M; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Rusinko A 3rd; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA., Culberson JC; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2017 Sep; Vol. 22 (8), pp. 995-1006. Date of Electronic Publication: 2017 Apr 20.
Autor:
Homsher MF; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Beshore DC; 2 Discovery Chemistry, Merck Research Labs, West Point, PA, USA., Cassaday J; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Squadroni B; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Mohammed E; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Hartnett M; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Day S; 3 MRL Pipeline Support, Merck and Co, Montreal, Canada., Ma L; 4 Neuroscience, Merck Research Labs, West Point, PA, USA., Pechter D; 5 Assay Operations, Merck Research Labs, Kenilworth, NJ, USA., Smith MD; 6 In Vitro Pharmacology, Merck and Co, Kenilworth, NJ, USA., Monsma F; 6 In Vitro Pharmacology, Merck and Co, Kenilworth, NJ, USA., Zuck P; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Finley MF; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Uebele VN; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA., Hermes JD; 1 Screening and Protein Sciences, Merck and Co, North Wales, PA, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2017 Sep; Vol. 22 (8), pp. 1060-1066. Date of Electronic Publication: 2017 Apr 20.