Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Homood As Sobeai"'
Autor:
Mohammed A. Assiri, Sahar R. Al Jumayi, Shuruq Alsuhaymi, Abdul-Hamid Emwas, Mariusz Jaremko, Nasser B. Alsaleh, Mohammed M. Al Mutairi, Ali A. Alshamrani, Homood As Sobeai, Hanan Alghibiwi
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 1, Pp 101897- (2024)
The steady increase in the use of electronic cigarettes (ECs) has reached an epidemic level, increasing mortality and morbidity, mainly due to pulmonary toxicity. Several mechanisms are involved in EC-induced toxicity, including oxidative stress and
Externí odkaz:
https://doaj.org/article/ba23cee86f8b4df0aba4b73312a26831
Publikováno v:
International journal of oncology. 60(6)
Cancer‑related deaths remain a challenging and devastating obstacle to defeat despite the tremendous advances in cancer treatment. Cancer metastasis is the major cause of these cancer‑related deaths. Metastasis involves sequential steps during ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f09abd1e14fc4931e5dd14831c55af4
https://pubmed.ncbi.nlm.nih.gov/35425991
https://pubmed.ncbi.nlm.nih.gov/35425991
Figure S4. Disease-free survival curves of overall NER gene expression at diagnosis in combined T-ALL and precursor-B-ALL. For the Low NER score group (dashed blue) versus high NER score group (solid red), 2 Kaplan Meier plots were generated for (A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ce1f32456b1ec0ba5485da59c21e6d
Figure S1. Linear regression models. (A) Linear regression model of cytogenetic abnormalities versus NER score. Staal and Hogan databases were combined, and cytogenetic abnormalities were categorized based on the prognosis a value of 0 = normal, 1 =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c9d4966ebc0d33408c16bbf87100db
Table S1. Patient information available from the two databases. (PDF 149 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf6f8f97644729a5cb3d4c0e8448c9e
Figure S3. Comparative Analysis of the 20 Canonical NER genes in the Staal dataset of only T-ALL patients. (A) In the early relapsers subgroup (n = 12) 12 genes were overexpressed at the time of relapse (gray bars, P = .371) versus diagnosis (black b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f88a121972dede3c04e3172d273a22
Table S2. Direction of matched diagnosis to relapse change of NER scores in relapsing ALL children. (PDF 53 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e750b8447253be2634c07a2f38c535
Figure S2. KM plots of cytogenetic abnormalities and NER scores. (A) KM plot of cytogenetic abnormalities. Staal and Hogan databases were combined, and cytogenetic abnormalities were categorized based on the prognosis a value of normal, favorable pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33db1a31b5c3c1c2cd07073af21fd78a
Publikováno v:
Cancer Research. 76:1552-1552
Double strand break repair and its relationship with genomic instability have been well studied in Acute Lymphocytic Leukemia (ALL). In contrast, base repair mechanisms, such as Nucleotide Excision Repair (NER) have not been well characterized in ALL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a6f5aa0ecdca3dfbeca3e95f562375
https://doi.org/10.1158/1538-7445.am2016-1552
https://doi.org/10.1158/1538-7445.am2016-1552
Autor:
Stephen G. Grant, Nancy Lalanne, Jean Johanna Latimer, Homood As Sobeai, Omar Ibrahim, Sharon L. Wenger, Jennifer Johnson
Publikováno v:
Cancer Research. 76:3589-3589
Genomic instability is a hallmark of human carcinogenesis. We have previously published that sporadic stage I breast tumors exhibit deficient Nucleotide Excision Repair (NER) capacity relative to non-diseased breast reduction primary cultures (Latime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386a111d2f557b33305dc9b93327260b
https://doi.org/10.1158/1538-7445.am2016-3589
https://doi.org/10.1158/1538-7445.am2016-3589