Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Homochlorcyclizine"'
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Instituto de Salud Carlos III (ISCIII)
New antiretroviral agents with alternative mechanisms are needed to complement the combination therapies used to treat HIV-1 infections. Here we report the identification of bioavailable molecules that interfere with the gene expression processes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2d37f138498d51d8e9c5586697b51c
https://hdl.handle.net/20.500.12105/10274
https://hdl.handle.net/20.500.12105/10274
Autor:
Chin-Tsun Chen, Te-Sheng Chang
Publikováno v:
Archives of Pharmacal Research. 35:119-127
The histamine receptor H1 antagonist homochlorcyclizine (HC) has been widely used as an antihistamine agent for the treatment of allergies. However, the effect of HC on skin pigmentation is not known. In the present study, we investigated the inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af902b41f718cb89844eb483e751e96a
https://doi.org/10.1007/s12272-012-0113-z
https://doi.org/10.1007/s12272-012-0113-z
Autor:
Ayako Kuriki, Akemi Marumo, Xiao-Pen Lee, Chika Hasegawa, Keizo Sato, Masaya Fujishiro, Takeshi Kumazawa, Hiroshi Seno
Publikováno v:
Rapid Communications in Mass Spectrometry. 20:537-543
Ten antihistamine drugs, diphenhydramine, orphenadrine, chlorpheniramine, diphenylpyraline, triprolidine, promethazine, homochlorcyclizine, cyproheptadine, cloperastine and clemastine, have been found to be extractable from human plasma samples using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9422bbbe51d2231b483936430bddd4
https://doi.org/10.1002/rcm.2335
https://doi.org/10.1002/rcm.2335
Autor:
Jun Kurai, Haruhiko Makino, Yutaka Hitsuda, Hirokazu Touge, Masanari Watanabe, Masanori Miyata, Masahiro Kodani, Takanori Sako, Hiroki Chikumi, Eiji Shimizu
Publikováno v:
Internal Medicine. 45:1011-1016
A 70-year-old man was admitted to our hospital because of dyspnea after taking an antihistaminic agent (homochlorcyclizine hydrochloride) for itching. Chest roentgenogram showed infiltration in the left lung field, and laboratory data revealed eosino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d0c475dda8d9b77f0627f84fef45a
https://doi.org/10.2169/internalmedicine.45.1674
https://doi.org/10.2169/internalmedicine.45.1674
Publikováno v:
Journal of Chromatography A. 1083:133-140
This paper describes the modification of Chiralcel OD column properties by adsorption of (+) or (-) camphorsulfonic acids (CSAs) used as additives to the mobile phase. The effects on retention, selectivity and efficiency, of adsorption of (+) and (-)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce712699e3907193671868107c19f203
https://doi.org/10.1016/j.chroma.2005.06.037
https://doi.org/10.1016/j.chroma.2005.06.037
Publikováno v:
Journal of Separation Science. 25:1175-1182
Separations of basic drug enantiomers by capillary electrophoresis have been investigated using methylated glucuronyl glucosyl β-cyclodextrin (Me GUG β-CD) as the chiral selector in the background electrolyte. Methylation was performed by reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131e47a2110934f86bf7605362885702
https://doi.org/10.1002/1615-9314(20021101)25:15/17<1175::aid-jssc1175>3.0.co
https://doi.org/10.1002/1615-9314(20021101)25:15/17<1175::aid-jssc1175>3.0.co
Autor:
Katsumi Miyazaki, Keishiro Miyake, Aki Nakai, Hitomi Fushida, Takaichi Arita, Mayumi Nishikata, Ken Iseki
Publikováno v:
Journal of Pharmacy and Pharmacology. 46:591-595
Concentrations of homochlorcyclizine enantiomers in blood, urine, and tissues of the liver, lung, kidney, brain, heart, spleen, intestine and stomach of rats after drug administration were determined by high-performance liquid chromatography on a chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a45ee93f2a0a41d1da16396511e990
https://doi.org/10.1111/j.2042-7158.1994.tb03863.x
https://doi.org/10.1111/j.2042-7158.1994.tb03863.x
Autor:
Mayumi Nishikata, Keishiro Miyake, Ken Iseki, Takaichi Arita, Katsumi Miyazaki, Hitomi Fushida, Aki Nakai
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:1267-1271
The enantioselective relationship between the pharmacokinetics and hepatic metabolism of homochlorcyclizine hydrochloride (HCZ) was investigated using rats. There were no significant differences in blood concentrations between the three forms after i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acca1e1ddd182fc67c56769e3f1be67e
https://doi.org/10.1248/bpb.17.1267
https://doi.org/10.1248/bpb.17.1267
Autor:
Keishiro Miyake, Aki Nakai, Akikazu Nomura, Hitomi Fushida, Takaichi Arita, Katsumi Miyazaki, Ken Iseki, Mayumi Nishikata
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 612:239-244
A method is described for the simultaneous determination of (+)- and (−)-homochlorcyclizine (HCZ) in human urine by high-performance liquid chromatography on a chiral stationary phase of ovomucoid-bonded silica. The pH of the buffer and organic mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61da813ae20ce89506e1b83cf1cff314
https://doi.org/10.1016/0378-4347(93)80169-5
https://doi.org/10.1016/0378-4347(93)80169-5
Publikováno v:
Journal of Pharmacobio-Dynamics. 14:87-93
Inhibitory effects of various histamine receptor-blocking agents including antiallergic agents on metabolic activations of neutrophils were examined by measuring leukotrienes (C4, D4 and E4) formation, arachidonic acid release and superoxide generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff1ac71f1a3600b1aca01002a30847f
https://doi.org/10.1248/bpb1978.14.87
https://doi.org/10.1248/bpb1978.14.87