Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Homira Behbahani"'
Autor:
Simone Tambaro, Sumonto Mitra, Ruchi Gera, Bengt Linderoth, Lars U. Wahlberg, Taher Darreh-Shori, Homira Behbahani, Per Nilsson, Maria Eriksdotter
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Alzheimer’s disease (AD) is an age-related disease characterized by altered cognition, neuroinflammation, and neurodegeneration against which there is presently no effective cure. Brain-derived neurotrophic factor (BDNF) is a ke
Externí odkaz:
https://doaj.org/article/2406ff59cd24486a931b518362b4d72b
Autor:
Mahmod Panahi, Yoshiki Hase, Xavier Gallart-Palau, Sumonto Mitra, Atsushi Watanabe, Roger C Low, Yumi Yamamoto, Diego Sepulveda-Falla, Atticus H Hainsworth, Masafumi Ihara, Siu Kwan Sze, Matti Viitanen, Homira Behbahani, Raj N Kalaria
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by NOTCH3 mutations. Typical CADASIL is characterised by subcortical ischemic strokes due to severe arteriopathy and fibrotic thic
Externí odkaz:
https://doaj.org/article/11dce6bfaaa44fa2b8315fb967bc1c18
Autor:
Sumonto Mitra, Ruchi Gera, Julia Sundheimer, Marine Lemee, Lars U. Wahlberg, Bengt Linderoth, Maria Eriksdotter, Homira Behbahani
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9011 (2022)
There is no cure yet available for Alzheimer’s disease (AD). We recently optimized encapsulated cell biodelivery (ECB) devices releasing human mature nerve growth factor (hmNGF), termed ECB-NGF, to the basal forebrain of AD patients. The ECB-NGF de
Externí odkaz:
https://doaj.org/article/8d76c8c6d6a84d4fb5480cc5df93b666
Autor:
Mahmod Panahi, Patricia Rodriguez Rodriguez, Seyed-Mohammad Fereshtehnejad, Donia Arafa, Nenad Bogdanovic, Bengt Winblad, Angel Cedazo-Minguez, Juha Rinne, Taher Darreh-Shori, Yoshiki Hase, Raj N. Kalaria, Matti Viitanen, Homira Behbahani
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Typical cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the human NOTCH3 gene. Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy i
Externí odkaz:
https://doaj.org/article/f0ffe195729647bdadfe04bd8db3b90f
Autor:
Sumonto Mitra, Silvia Turchetto, Winant Van Os, Lars U. Wahlberg, Bengt Linderoth, Homira Behbahani, Maria Eriksdotter
Publikováno v:
Cells, Vol 10, Iss 11, p 2834 (2021)
Alzheimer’s disease (AD) treatment is constrained due to the inability of peripherally administered therapeutic molecules to cross the blood–brain barrier. Encapsulated cell biodelivery (ECB) devices, a tissue-targeted approach for local drug rel
Externí odkaz:
https://doaj.org/article/e39d600451674b41b865b11435764563
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with abnormal protein modification, inflammation and memory impairment. Aggregated amyloid beta (Aβ) and phosphorylated tau proteins are medical diagnostic features. L
Externí odkaz:
https://doaj.org/article/208e4368ad3e49b087767da8af77adc3
Autor:
Swetha Vijayaraghavan, Azadeh Karami, Shahin Aeinehband, Homira Behbahani, Alf Grandien, Bo Nilsson, Kristina N Ekdahl, Rickard P F Lindblom, Fredrik Piehl, Taher Darreh-Shori
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65936 (2013)
Acetylcholine (ACh), the classical neurotransmitter, also affects a variety of nonexcitable cells, such as endothelia, microglia, astrocytes and lymphocytes in both the nervous system and secondary lymphoid organs. Most of these cells are very distan
Externí odkaz:
https://doaj.org/article/3c04f7e8fbc744c1ba9aaf71448958b7
Autor:
Susanne Frykman, Ji-Yeun Hur, Jenny Frånberg, Mikio Aoki, Bengt Winblad, Jarmila Nahalkova, Homira Behbahani, Lars O Tjernberg
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8948 (2010)
A key player in the development of Alzheimer's disease (AD) is the gamma-secretase complex consisting of at least four components: presenilin, nicastrin, Aph-1 and Pen-2. gamma-Secretase is crucial for the generation of the neurotoxic amyloid beta-pe
Externí odkaz:
https://doaj.org/article/9e22371927fa4938a8616fb043913923
Autor:
Anna Sandebring, Kelly Jean Thomas, Alexandra Beilina, Marcel van der Brug, Megan M Cleland, Rili Ahmad, David W Miller, Ibardo Zambrano, Richard F Cowburn, Homira Behbahani, Angel Cedazo-Mínguez, Mark R Cookson
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5701 (2009)
PTEN-induced novel kinase 1 (PINK1) mutations are associated with autosomal recessive parkinsonism. Previous studies have shown that PINK1 influences both mitochondrial function and morphology although it is not clearly established which of these are
Externí odkaz:
https://doaj.org/article/186a9b17a4b94e1aa0e80a3257dd5884
Autor:
Bengt Linderoth, Sumonto Mitra, Per Almqvist, Göran Lind, Helga Eyjolfsdottir, Homira Behbahani, Taher Darreh-Shori, Gera Ruchi, Erik Westman, Åke Seiger, Lars Wahlberg, Maria Eriksdotter
Publikováno v:
Neuromodulation: Technology at the Neural Interface. 25:S33-S34