Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Homero Sepulveda"'
Autor:
Sam D Sanderson, Marilyn L Thoman, Kornelia Kis, Elizabeth L Virts, Edgar B Herrera, Stephanie Widmann, Homero Sepulveda, Joy A Phillips
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40303 (2012)
The anaphylatoxin C5a is an especially potent mediator of both local and systemic inflammation. However, C5a also plays an essential role in mucosal host defense against bacterial, viral, and fungal infection. We have developed a response-selective a
Externí odkaz:
https://doaj.org/article/4a5b73a79a904400aed8a1153e0929ea
Autor:
Navin R Mahadevan, Veronika Anufreichik, Jeffrey J Rodvold, Kevin T Chiu, Homero Sepulveda, Maurizio Zanetti
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51845 (2012)
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth. However, the tumor-derived signals polarizing BMDC to a phenotype that subverts cell-mediated anti-tumor immunity have yet to be fully elucidated. A
Externí odkaz:
https://doaj.org/article/63faa7d2af8048af9cf570aed2b5be01
Autor:
Angela F. Drew, Homero Sepulveda, Steven S. Rossi, Jeffrey J. Rodvold, Maurizio Zanetti, Navin R. Mahadevan
Publikováno v:
Proceedings of the National Academy of Sciences. 108:6561-6566
Metabolic, infectious, and tumor cell-intrinsic noxae can all evoke the endoplasmic reticulum (ER) stress response in tumor cells, which is critical for tumor cell growth and cancer progression. Evidence exists that the ER stress response can drive a
Autor:
Mohamed Rachid Boulassel, Elias K. Haddad, Robert Balderas, Elias A. Said, Eric Delwart, Lydie Trautmann, Sylvain Gimmig, Homero Sepulveda, Benoit Bessette, Rafick Pierre Sekaly, Jean-Pierre Routy, Nicolas Chomont, Loury Janbazian
Publikováno v:
Nature Medicine. 12:1198-1202
The engagement of programmed death 1 (PD-1) to its ligands, PD-L1 and PD-L21,2,3,4, inhibits proliferation and cytokine production mediated by antibodies to CD3 (refs. 5,6,7). Blocking the PD-1–PD-L1 pathway in mice chronically infected with lympho
Autor:
Ralph M. Steinman, Sena Lee, Ming Guo, Homero Sepulveda, Michel C. Nussenzweig, Karsten Mahnke, Suzy L. Swain
Publikováno v:
The Journal of Cell Biology
Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC-205 multilectin receptor targets late endosomes or lysosomes rich in major histocompatibility complex class II (MHC II)
Autor:
Kevin Chiu, Navin R. Mahadevan, Homero Sepulveda, Maurizio Zanetti, Veronika Anufreichik, Jeffrey J. Rodvold
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51845 (2012)
PLoS ONE
PLoS ONE
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth. However, the tumor-derived signals polarizing BMDC to a phenotype that subverts cell-mediated anti-tumor immunity have yet to be fully elucidated. A
Autor:
Edgar B Herrera, Homero Sepulveda, Joy A. Phillips, Elizabeth L. Virts, Marilyn L. Thoman, Kornelia Kis, Sam D. Sanderson, Stephanie Widmann
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40303 (2012)
PLoS ONE, Vol 7, Iss 7, p e40303 (2012)
The anaphylatoxin C5a is an especially potent mediator of both local and systemic inflammation. However, C5a also plays an essential role in mucosal host defense against bacterial, viral, and fungal infection. We have developed a response-selective a
Publikováno v:
Biochemistry. 50(20)
The majority of protease – substrate assays rely on short, synthetic peptide substrates consisting of native or modified cleavage sequences. These assays are inadequate for interrogating the contribution of native substrate structure distal to a cl
Autor:
Zeling Cai, Jonathan Sprent, Homero Sepulveda, Inkyu Hwang, Weixing Shi, Young Yang, Michael R. Jackson, Per A. Peterson, Jing-Feng Huang
Publikováno v:
Science. 286:952-954
Peptide–major histocompatibility complex protein complexes (pMHCs) on antigen-presenting cells (APCs) are central to T cell activation. Within minutes of peptide-specific T cells interacting with APCs, pMHCs on APCs formed clusters at the site of T
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 378
Analytical cytometry has significant potential beyond cellular analysis. The inherent capability of flow cytometers to efficiently discriminate between uniformly sized particles based on their intrinsic properties provides the foundation for multiple