Výsledky vyhledávání - "Homer W. Fogle"

Interferons modulate mitogen-induced protein synthesis in airway smooth muscle

Autor: Vera P. Krymskaya, Jerome H. Taylor, Reynold A. Panettieri, Dmitry A. Goncharov, Amelia Chisolm, Andrew J. Eszterhas, Poay N. Lim, Elena A. Goncharova, Homer W. Fogle

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 299:L25-L35

Severe asthma is characterized by increased airway smooth muscle (ASM) mass due, in part, to ASM cell growth and contractile protein expression associated with increased protein synthesis. Little is known regarding the combined effects of mitogens an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66cd3de937450bcb02f8f05f86d7b72
https://doi.org/10.1152/ajplung.00228.2009

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Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1

Autor: Poay N. Lim, Vera P. Krymskaya, Huaqing Zhao, Gautam Damera, Audreesh Banerjee, Omar Tliba, Reynold A. Panettieri, Elena A. Goncharova, Homer W. Fogle

Publikováno v: British Journal of Pharmacology. 158:1429-1441

Background and purpose: Airway remodelling in asthma is manifested, in part, as increased airway smooth muscle (ASM) mass, reflecting myocyte proliferation. We hypothesized that calcitriol, a secosteroidal vitamin D receptor (VDR) modulator, would in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::230a28c065547a9e8f6a20eabe32407c
https://doi.org/10.1111/j.1476-5381.2009.00428.x

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RGS4 Modulates PDGF-Induced MMP-9 Expression In Human Airway Myocytes

Autor: Homer W. Fogle, Gautam Damera, Christopher E. Brightling, Kirk M. Druey, Yassine Amrani, Reynold A. Panettieri, Camille Doe

Publikováno v: C97. AIRWAY GOVERNANCE: THE AXIS OF AIRWAY MYOCYTES, MYOFIBROBLASTS AND EXTRACELLULAR MATRIX IN ASTHMATIC AND COPD REMODELING.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36579ffd41c156c3705d928fef4e55f6
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5334

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Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation

Autor: Hengjiang Zhao, Reynold A. Panettieri, Gautam Damera, Jose Freire, Homer W. Fogle, William Jester, Meiqi Jiang

Publikováno v: European journal of pharmacology. 649(1-3)

Airway hyperresponsiveness and inflammation characterize the airways of individuals with asthma and chronic obstructive pulmonary disease (COPD). Hence, therapeutic approaches that attenuate such manifestations may offer promise in the management of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22feac265bab7af4438634882db45c43
https://pubmed.ncbi.nlm.nih.gov/21417951

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Inhibition of myristoylated alanine-rich C kinase substrate (MARCKS) protein inhibits ozone-induced airway neutrophilia and inflammation

Autor: Homer W. Fogle, Angela Franciska Haczku, Indu Parikh, Hengjiang Zhao, Reynold A. Panettieri, William Jester, Edwin C. Murphy, Michael A. Mittelman, Gautam Damera, Meiqi Jiang

Evidence suggests inhibition of leukocyte trafficking mitigates, in part, ozone-induced inflammation. In the present study, the authors postulated that inhibition of myristoylated alanine-rich C kinase substrate (MARCKS), an 82-kDa protein with multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158dfe1af84c199a29076fd78401ebfa
https://europepmc.org/articles/PMC4064305/