Marked oestrus cycle-dependent regulation of rat arterial KV 7.4 channels driven by GPER1

Autor: Baldwin, SN, Forrester, EA, Homer, NZM, Andrew, R, Barrese, V, Stott, JB, Isakson, BE, Albert, AP, Greenwood, IA

BACKGROUND AND PURPOSE: Kcnq-encoded KV 7 channels (termed KV 7.1-5) regulate vascular smooth muscle cell (VSMC) contractility at rest and as downstream targets of receptor mediated responses. However, the current literature focuses predominantly on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::a7a5a9cf1a77c515f2f975cec0c69cc8

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Deletion of Hsd11b1 suppresses caloric restriction-induced bone marrow adiposity in male but not female mice.

Autor: Lovdel A; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Suchacki KJ; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Roberts F; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Sulston RJ; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Wallace RJ; Department of Orthopaedics, The University of Edinburgh, Edinburgh, UK., Thomas BJ; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Bell RMB; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Pruñonosa Cervera I; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Macpherson GJ; Department of Orthopaedic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK., Morton NM; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK.; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK., Homer NZM; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Chapman KE; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK., Cawthorn WP; University/BHF Centre for Cardiovascular Science, The University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, UK.

Publikováno v: The Journal of endocrinology [J Endocrinol] 2024 Jun 24; Vol. 262 (2). Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).

Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID-19.

Autor: Devine K; BHF/University Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh Bioquarter, University of Edinburgh, Edinburgh, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Russell CD; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK., Blanco GR; Edinburgh Cancer Research UK Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Walker BR; BHF/University Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh Bioquarter, University of Edinburgh, Edinburgh, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Homer NZM; BHF/University Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh Bioquarter, University of Edinburgh, Edinburgh, UK.; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Denham SG; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Simpson JP; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Leavy OC; Department of Population Health Sciences, University of Leicester, Leicester, UK., Elneima O; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., McAuley HJC; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Shikotra A; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Singapuri A; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Sereno M; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Saunders RM; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Harris VC; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Houchen-Wolloff L; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Greening NJ; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Lone NI; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Thorpe M; Centre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK., Greenhalf W; University of Liverpool, Liverpool, UK., Chalmers JD; Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Ho LP; MRC Human Immunology Unit, University of Oxford, Oxford, UK., Horsley A; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Marks M; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.; Hospital for Tropical Diseases, University College London Hospital, London, UK.; Division of Infection and Immunity, University College London, London, UK., Raman B; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Moore SC; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Dunning J; Pandemic Sciences Institute, University of Oxford, Oxford, UK., Semple MG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK., Andrew R; BHF/University Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh Bioquarter, University of Edinburgh, Edinburgh, UK.; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Evans RA; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Brightling CE; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Kenneth Baillie J; Division of Genetics and Genomics, Roslin Institute, University of Edinburgh, Edinburgh, UK., Reynolds RM; BHF/University Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh Bioquarter, University of Edinburgh, Edinburgh, UK.

Publikováno v: Clinical endocrinology [Clin Endocrinol (Oxf)] 2024 Apr; Vol. 100 (4), pp. 317-327. Date of Electronic Publication: 2024 Jan 17.