Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Homeostasis/immunology"'
Autor:
Haiping Wang, Taha Merghoub, Sarah-Maria Fendt, Camilla Jandus, Ping-Chih Ho, Xin Xie, Fabien Franco, Juan Fernández-García, Etienne Meylan, Ira Goldberg, Chin Hsien Tsai, Yao Chen Tsui, Isabell Schulze, Roy L. Silverstein, Roberta Zappasodi, Jedd D. Wolchok, Marcel P. Trefny, Alfred Zippelius, Florence Picard, Syed Raza Mohmood
Publikováno v:
Nature immunology, vol. 21, no. 3, pp. 298-308
Nature Immunology, Vol. 21, No 3 (2020) pp. 298-308
Nature Immunology
Nature Immunology, Vol. 21, No 3 (2020) pp. 298-308
Nature Immunology
Depleting regulatory T cells (T-reg cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0890f7d204d5ad48cba3ed61051edb49
https://pubmed.ncbi.nlm.nih.gov/32066948
https://pubmed.ncbi.nlm.nih.gov/32066948
Autor:
Jo A. Van Ginderachter, Xenia Geeraerts, Jiri Keirsse, Helena Van Damme, Geert Raes, Alain Beschin
The liver is a major target organ for metastasis of both gastrointestinal and extra-gastrointestinal cancers. Due to its frequently inoperable nature, liver metastasis represents a leading cause of cancer-associated death worldwide. In the past years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b465b3e3b42f59176fbcfa934cd83c4c
https://doi.org/10.1016/j.cellimm.2018.03.010
https://doi.org/10.1016/j.cellimm.2018.03.010
Autor:
Martinon, F.
Publikováno v:
Joint, bone, spine, vol. 85, no. 4, pp. 423-428
Key cellular functions including those related to energy metabolism, organization of the genetic information or production of membrane-bound and secreted proteins are compartmentalized within organelles. Various stresses such as differentiation progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::18df525ac2a5e3128929df97acae4c3b
https://serval.unil.ch/resource/serval:BIB_18E9EB64E09E.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_18E9EB64E09E.P001/REF.pdf
Autor:
Jo A. Van Ginderachter, Michelle Stakenborg, Gianluca Matteoli, Pedro J. Gomez-Pinilla, Evelien Labeeuw, Damya Laoui, Elisa Meroni, Kristin A. Sauter, Martina Di Giovangiulio, Francesca D'Errico, Gera Goverse, Yvon Elkrim, Giovanna Farro, Zofia M. Lisowski, Nathalie Stakenborg, David A. Hume, Guy E. Boeckxstaens
Publikováno v:
Farro, G, Stakenborg, M, Gomez-Pinilla, P J, Labeeuw, E, Goverse, G, Giovangiulio, M D, Stakenborg, N, Meroni, E, D'Errico, F, Elkrim, Y, Laoui, D, Lisowski, Z, Sauter, K A, Hume, D A, Van Ginderachter, J A, Boeckxstaens, G E & Matteoli, G 2017, ' CCR2-dependent monocyte-derived macrophages resolve inflammation and restore gut motility in postoperative ileus ', Gut, vol. 66, no. 12, pp. 2098-2109 . https://doi.org/10.1136/gutjnl-2016-313144
ObjectivePostoperative ileus (POI) is assumed to result from myeloid cells infiltrating the intestinalmuscularis externa(ME) in patients undergoing abdominal surgery. In the current study, we investigated the role of infiltrating monocytes in a murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0272ab7501966dc27f2a23e2d30bfb
https://www.pure.ed.ac.uk/ws/files/40021097/R1_GUT_submitted_files_24_02_2017.pdf
https://www.pure.ed.ac.uk/ws/files/40021097/R1_GUT_submitted_files_24_02_2017.pdf
Publikováno v:
Blaser, H, Dostert, C, Mak, T W & Brenner, D 2016, ' TNF and ROS Crosstalk in Inflammation ', Trends in Cell Biology, vol. 26, no. 4, pp. 249-261 . https://doi.org/10.1016/j.tcb.2015.12.002
Tumor necrosis factor (TNF) is tremendously important for mammalian immunity and cellular homeostasis. The role of TNF as a master regulator in balancing cell survival, apoptosis and necroptosis has been extensively studied in various cell types and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9494d1ba4ce531ec56f11ace5e73d383
https://portal.findresearcher.sdu.dk/da/publications/32ab6400-a948-4685-a025-3ad22c76247f
https://portal.findresearcher.sdu.dk/da/publications/32ab6400-a948-4685-a025-3ad22c76247f
Autor:
Nico van Rooijen, Daigo Hashimoto, Andrew Chow, Marylene Leboeuf, Masato Tanaka, Christoph Scheiermann, Daniel Lucas, Miriam Merad, Colette Prophete, Andrés Hidalgo, Paul S. Frenette, Simón Méndez-Ferrer, Michela Battista
Publikováno v:
Europe PubMed Central
Journal of Experimental Medicine, Vol. 208, No 2 (2011) pp. 261-271
The Journal of Experimental Medicine
Journal of Experimental Medicine, 208(2), 261-271. Rockefeller University Press
Chow, A, Lucas, D, Hidalgo, A, Mendez-Ferrer, S, Hashimoto, D, Scheiermann, C, Battista, M, Leboeuf, M, Prophete, C, van Rooijen, N, Tanaka, M, Merad, M & Frenette, P S 2011, ' Bone marrow CD169(+) macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche ', Journal of Experimental Medicine, vol. 208, no. 2, pp. 261-271 . https://doi.org/10.1084/jem.20101688
Journal of Experimental Medicine, Vol. 208, No 2 (2011) pp. 261-271
The Journal of Experimental Medicine
Journal of Experimental Medicine, 208(2), 261-271. Rockefeller University Press
Chow, A, Lucas, D, Hidalgo, A, Mendez-Ferrer, S, Hashimoto, D, Scheiermann, C, Battista, M, Leboeuf, M, Prophete, C, van Rooijen, N, Tanaka, M, Merad, M & Frenette, P S 2011, ' Bone marrow CD169(+) macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche ', Journal of Experimental Medicine, vol. 208, no. 2, pp. 261-271 . https://doi.org/10.1084/jem.20101688
Hematopoietic stem cells (HSCs) reside in specialized bone marrow (BM) niches regulated by the sympathetic nervous system (SNS). Here, we have examined whether mononuclear phagocytes modulate the HSC niche. We defined three populations of BM mononucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5299f89d89a892c4371ffd3864e816d0
https://doi.org/10.1084/jem.20101688
https://doi.org/10.1084/jem.20101688
Autor:
Carla Borri Voltattorni, Itamar Kass, Nathan Cowieson, Malcolm Buckle, David Perahia, Mauricio G. S. Costa, Daniel Christ, David B. Langley, David E. Hoke, Eugenia Pennacchietti, Ian R. Mackay, Oded Kleifeld, Cyril F. Reboul, Hervé Leh, Benjamin T. Porebski, Ashley M. Buckle, Julia M. McCoey, Brendan Roome, Daniela De Biase, Alessandro Paiardini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (25), pp.E2524-2529. ⟨10.1073/pnas.1403182111⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (25), pp.E2524-2529. ⟨10.1073/pnas.1403182111⟩
International audience; The human neuroendocrine enzyme glutamate decarboxylase (GAD) catalyses the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) using pyridoxal 5′-phosphate as a cofactor. GAD exists as two isoforms n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d16d55162420f70d6b6626fd7318824
https://hal-riip.archives-ouvertes.fr/pasteur-01146884
https://hal-riip.archives-ouvertes.fr/pasteur-01146884
Autor:
Gerhard Schenk, Thomas Huber, A. Ian Cassady, Jack U. Flanagan, Gregory M. Kelly, Jodie A. Robinson, Luke W. Guddat, David A. Hume, Jane E. Weber, Allan D. Burrows, Kieran S. Hadler
Publikováno v:
BMC Research Notes, Vol 1, Iss 1, p 78 (2008)
ResearcherID
Hadler, K S, Huber, T, Cassady, A I, Weber, J, Robinson, J, Burrows, A, Kelly, G, Guddat, L W, Hume, D A, Schenk, G & Flanagan, J U 2008, ' Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases? ', BMC Research Notes, vol. 1, pp. 78 .
BMC Research Notes
ResearcherID
Hadler, K S, Huber, T, Cassady, A I, Weber, J, Robinson, J, Burrows, A, Kelly, G, Guddat, L W, Hume, D A, Schenk, G & Flanagan, J U 2008, ' Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases? ', BMC Research Notes, vol. 1, pp. 78 .
BMC Research Notes
Background Tartrate-resistant acid phosphatases (TRAcPs), also known as purple acid phosphatases (PAPs), are a family of binuclear metallohydrolases that have been identified in plants, animals and fungi. The human enzyme is a major histochemical mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e979c8f61c91958b541301b89f6cb9f
http://eprints.maynoothuniversity.ie/3709/
http://eprints.maynoothuniversity.ie/3709/
Autor:
Dominique Ducrest-Gay, Ralf H. Adams, Beat A. Imhof, Michel Aurrand-Lions, Philippe Hammel, Claudia Zimmerli, P. Juillard, Georgia Gliki
Publikováno v:
The Journal of Pathology, Vol. 212, No 2 (2007) pp. 198-208
Jam-C(-/-) mice exhibit growth retardation and multilobular pneumonia concomitant with poor survival of the mice under conventional housing conditions. The deficient mice present a mega-oesophagus and have altered airway responsiveness. In addition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a12eb69518abaef64a109e5054f298
https://pubmed.ncbi.nlm.nih.gov/17455169
https://pubmed.ncbi.nlm.nih.gov/17455169
Autor:
Jesús Merino, Shozo Izui, Miguel A. González-Gay, Ramón Merino, Luis Buelta, Inés Santiuste, Esther Tamayo, Regina Marquina, Marcos López-Hoyos, J. González
Publikováno v:
Journal of Immunology, Vol. 178, No 5 (2007) pp. 2778-2786
ResearcherID
ResearcherID
Regulation of lymphocyte survival is essential for the maintenance of lymphoid homeostasis preventing the development of autoimmune diseases. Recently, we described a systemic lupus erythematosus associated with an IgA nephropathy in autoimmune-prone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0096b6460e72aa4bd6cebee01f95961
https://pubmed.ncbi.nlm.nih.gov/17312121
https://pubmed.ncbi.nlm.nih.gov/17312121