Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Homeodomain Proteins/genetics/*metabolism"'
Autor:
Antonina Hafner, Gerald R. Crabtree, Christopher M. Weber, Jacob G. Kirkland, Benjamin Z. Stanton, Alistair N. Boettiger, Simon M. G. Braun
Publikováno v:
Nature Structural & Molecular Biology, Vol. 28, No 6 (2021) pp. 501-511
Nat Struct Mol Biol
Nat Struct Mol Biol
The mammalian SWI/SNF complex, or BAF complex, has a conserved and direct role in antagonizing Polycomb-mediated repression. Yet, BAF also promotes repression by Polycomb in stem cells and cancer. How BAF both antagonizes and promotes Polycomb-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d553f63fe89284877c325a5813a60c66
https://archive-ouverte.unige.ch/unige:154515
https://archive-ouverte.unige.ch/unige:154515
Autor:
Matsuda, T., Irie, T., Katsurabayashi, S., Hayashi, Y., Nagai, T., Hamazaki, N., Adefuin, A. M. D., Miura, F., Ito, T., Kimura, Hiroshi, Shirahige, K., Takeda, T., Iwasaki, K., Imamura, T., Nakashima, K.
Publikováno v:
Neuron. 101(No. 3)
Summary Minimal sets of transcription factors can directly reprogram somatic cells into neurons. However, epigenetic remodeling during neuronal reprogramming has not been well reconciled with transcriptional regulation. Here we show that NeuroD1 achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff462e708aebdf360cf59f019e9a0f3
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100822271
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100822271
Autor:
Marc Y. Donath, Anne Wojtusciszyn, Bernhard O. Boehm, Kai Hui Hu He, Kathrin Maedler, Piero Marchetti, Nadine S. Sauter, Roberto Lupi, Benoit R. Gauthier, Thierry Brun
Publikováno v:
BASE-Bielefeld Academic Search Engine
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
We previously demonstrated that the transcription factor Pax4 is important for beta-cell replication and survival in rat islets. Herein, we investigate Pax4 expression in islets of non-diabetic and diabetic donors, its regulation by mitogens, glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c9b2c00f8a68d3a9851326c5e5a334
http://doc.rero.ch/record/299485/files/ddm325.pdf
http://doc.rero.ch/record/299485/files/ddm325.pdf
Autor:
Caroline Poisson, Mounia Heddad Masson, Jacques Philippe, Yvan Gosmain, Audrey Guérardel, Claire Cheyssac
Publikováno v:
Endocrinology, Vol. 153, No 9 (2012) pp. 4204-15
The Pax6 transcription factor is crucial for pancreatic α-cells. Indeed, Pax6-deficient mouse models are characterized by markedly altered α-cell differentiation. Our objective was to investigate the role of Pax6 in glucagon secretion process. We u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4e08a66a1b2e4c08788194ee66248e
https://doi.org/10.1210/en.2012-1425
https://doi.org/10.1210/en.2012-1425
Autor:
Asllan Gjinovci, Carmen M. Jimenez Moreno, Claes B. Wollheim, Kai Hui Hu He, Deborah Aeberhard, Fabrizio Thorel, Marion Cornu, Benoit R. Gauthier, Petra I. Lorenzo, Jorge Vallejo Ortega, Pedro Luis Herrera, Thierry Brun, Bernard Thorens, Paolo Meda
Publikováno v:
Diabetes
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes; Vol 60
Diabetes, vol. 60, no. 6, pp. 1705-1715
Digital.CSIC. Repositorio Institucional del CSIC
instname
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes; Vol 60
Diabetes, vol. 60, no. 6, pp. 1705-1715
Digital.CSIC. Repositorio Institucional del CSIC
instname
et al.
[Objective]: To establish the role of the transcription factor Pax4 in pancreatic islet expansion and survival in response to physiological stress and its impact on glucose metabolism, we generated transgenic mice conditionally and select
[Objective]: To establish the role of the transcription factor Pax4 in pancreatic islet expansion and survival in response to physiological stress and its impact on glucose metabolism, we generated transgenic mice conditionally and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43996fb6545ff2cf025baf9d4ab3104
https://doi.org/10.2337/db10-1102
https://doi.org/10.2337/db10-1102
Autor:
Duncan Baker, Anne-Marie Strömberg, Susanne Ström, Anis Feki, Björn Rozell, Rosita Bergström, Outi Hovatta, Frida Holm, José Inzunza
Publikováno v:
Human Reproduction (Oxford, England)
Human Reproduction, Vol. 25, No 5 (2010) pp. 1271-9
Human Reproduction, Vol. 25, No 5 (2010) pp. 1271-9
background: Both human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) bear a great potential in regenerative medicine. In addition to optimized clinical grade culture conditions, efficient clinical grade cryopreservation meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151fd2063aede2edba3c20d2d87f22c0
https://doi.org/10.1093/humrep/deq040
https://doi.org/10.1093/humrep/deq040
Autor:
Philippe A. Halban, Beate Ritz-Laser, Benoit R. Gauthier, Jacques Philippe, Didier Trono, Aline Mamin, Anne Estreicher, Frédéric Ris, Thierry Brun, Patrick Salmon
Publikováno v:
Diabetologia, Vol. 46, No 6 (2003) pp. 810-821
AIMS/HYPOTHESIS: The transcription factor Pdx1 is required for the development and differentiation of all pancreatic cells. Beta-cell specific inactivation of Pdx1 in developing or adult mice leads to an increase in glucagon-expressing cells, suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6506f941058bd9a4df594566d7c8d3a5
https://doi.org/10.1007/s00125-003-1115-7
https://doi.org/10.1007/s00125-003-1115-7
Autor:
Mark A. Magnuson, Weiping Yuan, Klaus H. Kaestner, Brandon L. Taylor, Jacqueline R. Benthuysen, Catherine Lee May, Pedro Luis Herrera, Fabrizio Thorel, Jingxuan Liu, Ashleigh E. Schaffer, Yang Jiao, Maike Sander
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003274 (2013)
PLoS Genetics
PLOS Genetics, Vol. 9, No 1 (2013) P. e1003274
PLoS Genetics
PLOS Genetics, Vol. 9, No 1 (2013) P. e1003274
All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f76441d64224df86e7ff6a7ed2b329f
http://europepmc.org/articles/PMC3561089?pdf=render
http://europepmc.org/articles/PMC3561089?pdf=render
Publikováno v:
Retrovirology
Retrovirology, vol. 9, pp. 111
Retrovirology, Vol 9, Iss 1, p 111 (2012)
Retrovirology, vol. 9, pp. 111
Retrovirology, Vol 9, Iss 1, p 111 (2012)
Background Certain post-translational modifications to histones, including H3K4me3, as well as binding sites for the transcription factor STAT1, predict the site of integration of exogenous gamma-retroviruses with great accuracy and cell-type specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed02b73aee8a78960b07d6a403a0007
https://pubmed.ncbi.nlm.nih.gov/23253934
https://pubmed.ncbi.nlm.nih.gov/23253934
Autor:
Ruiz Altaba, Ariel
Publikováno v:
Science Signaling, Vol. 4, No 200 (2011) P. pt9
The Hedgehog (Hh)-Gli signaling pathway is an essential pathway involved in development and cancer. It controls the Gli code-the sum of all activator and repressor functions of the Gli transcription factors. Through the Gli code, and Gli1 in particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::baf77ce19ff313855d9ac5b1d549fc28
https://pubmed.ncbi.nlm.nih.gov/22114144
https://pubmed.ncbi.nlm.nih.gov/22114144