Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production.

Autor: Kiyuna LA; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Krishnamurthy KA; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Homan EB; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Langelaar-Makkinje M; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Gerding A; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bos T; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Oosterhuis D; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands., Overduin RJ; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Metabolic Diseases, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Schreuder AB; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Metabolic Diseases, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., de Meijer VE; Section of HPB Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Olinga P; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, The Netherlands., Derks TGJ; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Metabolic Diseases, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Eunen K; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Bakker BM; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. b.m.bakker01@umcg.nl., Oosterveer MH; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. moosterveer@hotmail.com.; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. moosterveer@hotmail.com.

Publikováno v: Communications biology [Commun Biol] 2024 Nov 09; Vol. 7 (1), pp. 1479. Date of Electronic Publication: 2024 Nov 09.