Antiviral activity of bovine type III interferon against bovine viral diarrhea virus is greatly reduced in bovine turbinate cells due to limited expression of IFN lambda receptor 1 (IL-28Rα).

Autor: Dassanayake RP; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States., Menghwar H; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States.; ARS Research Participation Program, Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States., Bickel KA; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States., Holthausen DJ; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States., Ma H; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States., Diaz-San Segunda F; Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States., Rodriguez-Calzada M; Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States., Medina GN; Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States.; National Bio and Agro-Defense Facility (NBAF), ARS, USDA, Manhattan, KS, United States., Attreed S; Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States., Falkenberg SM; Sugg Laboratory, Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States., Kanipe C; Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA, United States., Sacco RE; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States., De Los Santos T; Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States., Casas E; Ruminant Diseases and Immunology Research Unit, Agricultural Research Service, National Animal Disease Center, United States Department of Agriculture, Ames, IA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Aug 19; Vol. 15, pp. 1441908. Date of Electronic Publication: 2024 Aug 19 (Print Publication: 2024).

The amphibian peptide Yodha is virucidal for Zika and dengue viruses.

Autor: Lee SH; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA., Kim EH; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA.; Viral Immunology Laboratory, Institut Pasteur Korea, Seongnam, Republic of Korea., O'neal JT; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA.; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Dale G; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA., Holthausen DJ; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA., Bowen JR; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA.; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Quicke KM; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA.; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Skountzou I; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA., Gopal S; Rajiv Gandhi Center for Biotechnology, Poojapura, Thiruvananthapuram, Kerala, 695014, India., George S; Rajiv Gandhi Center for Biotechnology, Poojapura, Thiruvananthapuram, Kerala, 695014, India., Wrammert J; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Suthar MS; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA.; Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA., Jacob J; Emory Vaccine Center, Yerkes National Primate Center, Emory University, 954 Gatewood Road, Atlanta, GA, 30329, USA. jjacob3@emory.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 602. Date of Electronic Publication: 2021 Jan 12.

The bactericidal effect of a complement-independent antibody is osmolytic and specific to Borrelia.

Autor: LaRocca TJ; Department of Molecular Genetics and Microbiology, Center for Infectious Diseases, Stony Brook University, Stony Brook, NY 11794-5120, USA., Holthausen DJ, Hsieh C, Renken C, Mannella CA, Benach JL

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Jun 30; Vol. 106 (26), pp. 10752-7. Date of Electronic Publication: 2009 Jun 19.