DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients

Autor: Olsen MB, Huse C, Sousa MMLD, Murphy SL, Sarno A, Obermann TS, Yang K, Holter JC, Jørgensen MJ, Christensen EE, Wang W, Ji P, Heggelund L, Hoel H, Dyrhol-Riise AM, Gregersen I, Aukrust P, Bjørås M, Halvorsen B, Dahl TB

Publikováno v: Journal of Inflammation Research, Vol Volume 15, Pp 6629-6644 (2022)

Maria Belland Olsen,1,2 Camilla Huse,1,2 Mirta Mittelstedt Leal de Sousa,3,4 Sarah Louise Murphy,1,2 Antonio Sarno,3,5 Tobias Sebastian Obermann,3 Kuan Yang,1 Jan Cato Holter,2,6 Marte Jøntvedt Jørgensen,2,7 Erik Egeland Christensen,2,7 Wei Wang,3

Externí odkaz: https://doaj.org/article/f13c0e2d10f345eaabdb17061ea53946

Mapping the human genetic architecture of COVID-19

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Publikováno v: NATURE
Initiative, COVID H G & Dark, P 2021, ' Mapping the human genetic architecture of COVID-19. ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
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Nature, vol 600, iss 7889
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COVID-19 Host Genetics Initiative 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature, 2021, 600 (7889), pp.472-477. ⟨10.1038/s41586-021-03767-x⟩
Nature, Vol. 600, no. ²7889, p. 472-477 (2021)
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Nature, vol. 600, no. 7889, pp. 472-477
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Niemi, M E K, Karjalainen, J, Liao, R G, Neale, B M, Daly, M, Ganna, A, Pathak, G A, Andrews, S J, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E C, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M A, Wendt, F R, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M J, Smith, G D, Willer, C J, Buxbaum, J D, Karjalainen, J, Mehtonen, J, Folkersen, L, Moltke, I, Hinney, A, Wang, C, Ellinghaus, D, Brunak, S, Castro, P, Guindo-Martinez, M, Lee, J Y, Loos, R J F, Zhao, J H, Sun, Y V, Wang, B, Parker, R, Garcia, S M, Smith, O, Davis, C, COVID-19 Host Genetics Initiative, 23andMe COVID-19 Team, Norwegian SARS-CoV-2 Study Grp, Humanitas COVID-19 Task Force, Humanitas Gavazzeni COVID-19 Task, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Genes & Hlth Res Team & UCLA Hlth ATLAS Data Mart Working 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature (Lond.) 600 (2021): 472–+. doi:10.1038/s41586-021-03767-x
info:cnr-pdr/source/autori:Mari E. K. Niemi; Juha Karjalainen; Rachel G. Liao; Benjamin M. Neale; Mark Daly; Andrea Ganna; COVID-19 Host Genetics Initiative and the GEN-COVID Multicenter Study (including Stella, Alessandra and Biscarini, Filippo)/titolo:Mapping the human genetic architecture of COVID-19/doi:10.1038%2Fs41586-021-03767-x/rivista:Nature (Lond.)/anno:2021/pagina_da:472/pagina_a:+/intervallo_pagine:472–+/volume:600
Ganna, A & Davey Smith, G 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Nature 600, 472-477 (2021)
Baillie, J K, Wilson, J F, Bulteel, N, Hayward, C, Klaric, L, Porteous, D J, Russell, C D, Tenesa, A, Norman, L & Scott-Brown, J & Swann, O 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x

Niemi, Mari E. K. et al. 39 páginas, figuras y tablas. Contiene material suplementario.
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974d087615705cffb4d0d7bdc6394ffc
https://eprints.soton.ac.uk/456122/

Rapid low-cost assembly of modular microvessel-on-a-chip with benchtop xurography.

Autor: Agarwal SS; Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA. song.1069@osu.edu., Cortes-Medina M; Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA., Holter JC; Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA., Avendano A; Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA., Tinapple JW; Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA., Barlage JM; Department of Biomedical Education and Anatomy, The Ohio State University, Columbus, OH 43210, USA., Menyhert MM; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA., Onua LM; Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA., Song JW; Department of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA. song.1069@osu.edu.; The Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

Publikováno v: Lab on a chip [Lab Chip] 2024 Oct 22; Vol. 24 (21), pp. 5065-5076. Date of Electronic Publication: 2024 Oct 22.

Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections.

Autor: Alirezaylavasani A; Department of Immunology, Oslo University Hospital, Oslo, Norway.; KG Jebsen Centre for B Cell Malignancies, University of Oslo, Oslo, Norway.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway., Skeie LG; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Egner IM; Department of Immunology, Oslo University Hospital, Oslo, Norway.; KG Jebsen Centre for B Cell Malignancies, University of Oslo, Oslo, Norway.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway., Chopra A; Department of Immunology, Oslo University Hospital, Oslo, Norway.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway.; ImmunoLingo Convergence Center, University of Oslo, Oslo, Norway., Dahl TB; Department of Immunology, Oslo University Hospital, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Prebensen C; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Vaage JT; Department of Immunology, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Halvorsen B; Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Lund-Johansen F; Department of Immunology, Oslo University Hospital, Oslo, Norway.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway.; ImmunoLingo Convergence Center, University of Oslo, Oslo, Norway., Tonby K; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Reikvam DH; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Stiksrud B; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Holter JC; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Dyrhol-Riise AM; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Munthe LA; Department of Immunology, Oslo University Hospital, Oslo, Norway. l.a.munthe@medisin.uio.no.; KG Jebsen Centre for B Cell Malignancies, University of Oslo, Oslo, Norway. l.a.munthe@medisin.uio.no.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway. l.a.munthe@medisin.uio.no., Kared H; Department of Immunology, Oslo University Hospital, Oslo, Norway. hassen.kared@medisin.uio.no.; KG Jebsen Centre for B Cell Malignancies, University of Oslo, Oslo, Norway. hassen.kared@medisin.uio.no.; Precision Immunotherapy Alliance, University of Oslo, Oslo, Norway. hassen.kared@medisin.uio.no.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Oct 09; Vol. 9 (1), pp. 185. Date of Electronic Publication: 2024 Oct 09.

Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients.

Autor: Barratt-Due A; Department of Anesthesia and Intensive Care Medicine, Oslo University Hospital, Oslo, Norway., Pettersen K; Research Laboratory, Nordland Hospital Trust, Bodø, Norway., Børresdatter-Dahl T; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway., Holter JC; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Grønli RH; Research Laboratory, Nordland Hospital Trust, Bodø, Norway., Dyrhol-Riise AM; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Lerum TV; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway., Holten AR; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway., Tonby K; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Trøseid M; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, University of Oslo, Oslo, Norway., Skjønsberg OH; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway., Granerud BK; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Heggelund L; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.; Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway., Kildal AB; Department of Anesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway.; Department of Clinical Medicine, Faculty of Health Sciences, UIT-The Arctic University of Norway, Tromsø, Norway., Schjalm C; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Immunology, Oslo University Hospital, Oslo, Norway., Aaløkken TM; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway., Aukrust P; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, University of Oslo, Oslo, Norway., Ueland T; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway., Mollnes TE; Research Laboratory, Nordland Hospital Trust, Bodø, Norway.; Department of Immunology, Oslo University Hospital, Oslo, Norway., Halvorsen B; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.

Publikováno v: Journal of internal medicine [J Intern Med] 2024 Jul; Vol. 296 (1), pp. 80-92. Date of Electronic Publication: 2024 Mar 27.