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Akademický článek

Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist.

Autor: May JA; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Sharif NA; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., McLaughlin MA; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Chen HH; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Severns BS; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Kelly CR; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Holt WF; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Young R; Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University , Box 980540, Richmond, Virginia 23298, United States., Glennon RA; Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University , Box 980540, Richmond, Virginia 23298, United States., Hellberg MR; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States., Dean TR; Ophthalmology Discovery Research, Alcon Research, Ltd. , 6201 South Freeway, Fort Worth, Texas 76134, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2015 Nov 25; Vol. 58 (22), pp. 8818-33. Date of Electronic Publication: 2015 Nov 09.

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Akademický článek

Neuregulins as potential drugs for neurological disorders.

Autor: Marchionni MA; Cambridge NeuroScience, Inc., Massachusetts 01239, USA., Kirk CJ, Isaacs IJ, Hoban CJ, Mahanthappa NK, Anton ES, Chen C, Wason F, Lawson D, Hamers FP, Canoll PD, Reynolds R, Cannella B, Meun D, Holt WF, Matthew WD, Chen LE, Gispen WH, Raine CS, Salzer JL, Gwynne DI

Publikováno v: Cold Spring Harbor symposia on quantitative biology [Cold Spring Harb Symp Quant Biol] 1996; Vol. 61, pp. 459-72.

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Akademický článek

Examining the concordance of retinal ganglion cell counts generated using measures of structure and function.

Autor: Stapley, Victoria¹ (AUTHOR) v.stapley@ulster.ac.uk, Anderson, Roger S.^1,2 (AUTHOR), Saunders, Kathryn¹ (AUTHOR), Mulholland, Pádraig J.^1,2 (AUTHOR)

Publikováno v: Ophthalmic & Physiological Optics. Nov2022, Vol. 42 Issue 6, p1338-1352. 15p. 3 Diagrams, 4 Charts, 4 Graphs.

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Akademický článek

Discovery of inhibitors of human renin with high oral bioavailability.

Autor: Hoover DJ; Department of Medicinal Chemistry, Pfizer Inc, Groton, CT 06340, USA., Lefker BA, Rosati RL, Wester RT, Kleinman EF, Bindra JS, Holt WF, Murphy WR, Mangiapane ML, Hockel GM, et. al.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 1995; Vol. 362, pp. 167-80.

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Akademický článek

CP-71,362: a pentapeptide renin inhibitor selective for the canine enzyme.

Autor: Mangiapane ML; Department of Cardiovascular and Metabolic Diseases, Pfizer Central Research, Groton, CT 06340., MacAndrew JT, Ellery SS, Smith AH, Purcell IM, Kleinman EF, Holt WF, Murphy WR

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 1994 Jul; Vol. 16 (4), pp. 507-33.

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