Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Holt N. Murray"'
Publikováno v:
JTCVS Techniques. 13:131-134
Autor:
Neena Chandrasekaran, Syed Mahmood, Hernando Gomez, Holt N. Murray, Joseph A. Carcillo, Renee Anderko, John A. Kellum
Publikováno v:
Critical Care Medicine. 46:730-730
Publikováno v:
Resuscitation. 55:329-336
Previous studies suggest glucose, insulin and potassium (GIK) infusion during ischemia reduces infarct size and improves post-ischemic myocardial function in acute myocardial infarction and following surgical revascularization of the heart. The poten
Autor:
Anne J. Baird, Paul G. Sleph, Holt N. Murray, W L Rogers, F L Wang, Gary J. Grover, David W. Green
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 274:H90-H97
Mitochondrial F1F0adenosinetriphosphatase (ATPase) is responsible for the majority of ATP synthesis during normoxic conditions, but under ischemic conditions it accounts for significant ATP hydrolysis. A previous study showed that preconditioning in
Autor:
Petr Paucek, Gary J. Grover, Vladimir Yarov-Yarovoy, Raymond B. Darbenzio, Holt N. Murray, Nicholas J. Lodge, Keith D. Garlid, Mark A. Smith, Albert J. D'Alonzo
Publikováno v:
Circulation Research. 81:1072-1082
Abstract Previous studies showed a poor correlation between sarcolemmal K + currents and cardioprotection for ATP-sensitive K + channel (K ATP ) openers. Diazoxide is a weak cardiac sarcolemmal K ATP opener, but it is a potent opener of mitochondrial
Autor:
Karnail S. Atwal, Gary J. Grover, Holt N. Murray, Mary W. Wilde, S Dzwonczyk, Carol A. Sargent, Jeffrey G. Tuttle
Publikováno v:
Cardiovascular Research. 31:270-277
Objectives: A myocardial calcium-independent PLA2 has been described that is activated during myocardial ischemia and this enzyme may modulate ATP-sensitive potassium channels (KATP). The aim of this study was to determine the effect of an inhibitor
Publikováno v:
Critical Care
Is a health care provider's most proximal obligation to individuals or society as a whole? Our International panel of critical care providers grapple over the issue of whether patient–physician confidentiality exists as an open ended ideal it shoul
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 283(4)
We studied the differences between the functional and bioenergetic effects of antioxidants (AOX) administered before or after myocardial ischemia. Sprague-Dawley rat hearts were perfused with a modified Krebs-Henseleit solution and bubbled with 95% O
Publikováno v:
Critical care medicine. 30(2)
OBJECTIVE To determine relative adenine nucleotide regeneration and improvement in left ventricular (LV) function using three commonly used adrenergic agents--epinephrine, dobutamine, and phenylephrine---during reperfusion after a period of global is
Publikováno v:
European journal of pharmacology. 277(2-3)
Blockers of ATP-sensitive K + channels (K ATP ) abolish preconditioning in several species. Glyburide does not abolish preconditioning in rat hearts, but this may be due to a loss of its activity during ischemia. We determined the effect of a K ATP b