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pro vyhledávání: '"Holt, CE"'
Autor:
Holt, CE
The tips of axons are often far away from the cell soma where most proteins are synthesized. Recent work has revealed that axonal mRNA transport and localised translation are key regulatory mechanisms that allow these distant outposts of the cell to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b477a2895266996c3d6a05672a2f59
https://www.repository.cam.ac.uk/handle/1810/287877
https://www.repository.cam.ac.uk/handle/1810/287877
Autor:
St George-Hyslop, PH, Qamar, S, Wang, Guozhen, Randle, SJ, Ruggeri, Francesco Simone, Varela, Juan, Kaminski, CF, Kaminski, GS, Vendruscolo, M, Knowles, TPJ, Klenerman, D, Holt, CE, Lin, Q, Meadows, William
Reversible phase separation, which underpins the role of FUS in ribonucleoprotein granules and other membrane-free organelles, is in part driven by the intrinsically disordered low complexity (LC) domain of FUS. Here, we report that cooperative catio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e149434a94dcae6a5baaf8fc21f00548
Autor:
Cioni, Jean-Michel, Wong, Hovy Ho-Wai, Bressan, Dario, Kodama, Lay, Harris, William A, Holt, CE
The axons of retinal ganglion cells (RGCs) are topographically sorted before they arrive at the optic tectum. This pre-target sorting, typical of axon tracts throughout the brain, is poorly understood. Here, we show that Cytoplasmic FMR1-Interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658b07d074c9c67f4cf8bd5a6d6e0f87
Fluorescence anisotropy imaging microscopy (FAIM) measures the depolarization properties of fluorophores to deduce molecular changes in their environment. For successful FAIM, several design principles have to be considered and a thorough system-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df0921c578a0f7e012bb9f165e3e5f4
Autor:
Holt, CE, Wong, H-W, Lin, Q, Stroehl, F, Roque, CG, Cioni, JM, Cagnetta, R, Turner-Bridger, B, Laine, R, Harris, WA, Kaminski, CF
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major determinant of synaptic connectivity, is shaped by localized growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4671364727ecbdc5429b580ea81c1101
Autor:
*%2C‡<%2Fce%3Asup>%2C+Rong+J%2E%22">Guan §<%2Fce%3Asup>%2C+Yineng%22">Fu ∥<%2Fce%3Asup>%2C+Peter+R%2E%22">Holt ‡<%2Fce%3Asup>%2C+Arthur+B%2E%22">Pardee