Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Holstege, Frank CP"'
Autor:
Aristizabal, Maria J, Dever, Kristy, Negri, Gian Luca, Shen, Mary, Hawe, Nicole, Benschop, Joris J, Holstege, Frank CP, Krogan, Nevan J, Sadowski, Ivan, Kobor, Michael S
Publikováno v:
The Journal of biological chemistry, vol 294, iss 44
Fcp1 is a protein phosphatase that facilitates transcription elongation and termination by dephosphorylating the C-terminal domain of RNA polymerase II. High-throughput genetic screening and gene expression profiling of fcp1 mutants revealed a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::8525a14c284231aed96c0b9fde21a6e9
https://escholarship.org/uc/item/23g2m1hg
https://escholarship.org/uc/item/23g2m1hg
Autor:
Apweiler Eva, Sameith Katrin, Margaritis Thanasis, Brabers Nathalie, van de Pasch Loes, Bakker Linda V, van Leenen Dik, Holstege Frank CP, Kemmeren Patrick
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 239 (2012)
Abstract Background Cellular glucose availability is crucial for the functioning of most biological processes. Our understanding of the glucose regulatory system has been greatly advanced by studying the model organism Saccharomyces cerevisiae, but m
Externí odkaz:
https://doaj.org/article/21a6d90ef4fa416b9307cdc26e2ffcd6
Autor:
Stulemeijer Iris JE, Pike Brietta L, Faber Alex W, Verzijlbergen Kitty F, van Welsem Tibor, Frederiks Floor, Lenstra Tineke L, Holstege Frank CP, Gasser Susan M, van Leeuwen Fred
Publikováno v:
Epigenetics & Chromatin, Vol 4, Iss 1, p 2 (2011)
Abstract Background Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both gene repression and activation. To eliminate indirect effects and examine the direct consequences of Dot1 bind
Externí odkaz:
https://doaj.org/article/fdfd35f69dff4c459cb72a7cc498a6be
Publikováno v:
Molecular Systems Biology; Oct2020, Vol. 16 Issue 10, p1-16, 16p
Autor:
Braberg, Hannes, Jin, Huiyan, Moehle, Erica A, Chan, Yujia A, Wang, Shuyi, Shales, Michael, Benschop, Joris J, Morris, John H, Qiu, Chenxi, Hu, Fuqu, Tang, Leung K, Fraser, James S, Holstege, Frank CP, Hieter, Philip, Guthrie, Christine, Kaplan, Craig D, Krogan, Nevan J
Publikováno v:
Cell, vol 154, iss 4
RNA polymerase II (RNAPII) lies at the core of dynamic control of gene expression. Using 53 RNAPII point mutants, we generated a point mutant epistatic miniarray profile (pE-MAP) comprising ∼60,000 quantitative genetic interactions in Saccharomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::100a66fb127bef674ff9a394cce38215
https://escholarship.org/uc/item/6v60k8t9
https://escholarship.org/uc/item/6v60k8t9
Autor:
Steller, Ernst JA, Raats, Danielle A, Koster, Jan, Rutten, Bert, Govaert, Klaas M, Emmink, Benjamin L, Snoeren, Nikol, van Hooff, Sander R, Holstege, Frank CP, Maas, Coen, Borel Rinkes, Inne HM, Kranenburg, Onno
In epithelial tumors, the platelet-derived growth factor receptor B (PDGFRB) is mainly expressed by stromal cells of mesenchymal origin. Tumor cells may also acquire PDGFRB expression following epithelial-to-mesenchymal transition (EMT), which occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86ef195db684124c7ccb65cc0813326b
https://europepmc.org/articles/PMC3579322/
https://europepmc.org/articles/PMC3579322/
Autor:
Leusink, Frank KJ, van Es, Robert JJ, de Bree, Remco, de Jong, Robert J Baatenburg, van Hooff, Sander R, Holstege, Frank CP, Slootweg, Piet J, Brakenhoff, Ruud H, Takes, Robert P
Publikováno v:
In Lancet Oncology December 2012 13(12):e554-e561
Autor:
Jonge, Wim J, O'Duibhir, Eoghan, Lijnzaad, Philip, Leenen, Dik, Groot Koerkamp, Marian JA, Kemmeren, Patrick, Holstege, Frank CP
Publikováno v:
EMBO Journal; 2/1/2017, Vol. 36 Issue 3, p274-290, 17p
Autor:
O'Duibhir, Eoghan, Lijnzaad, Philip, Benschop, Joris J, Lenstra, Tineke L, Leenen, Dik, Groot Koerkamp, Marian JA, Margaritis, Thanasis, Brok, Mariel O, Kemmeren, Patrick, Holstege, Frank CP
Publikováno v:
Molecular Systems Biology; Jun2014, Vol. 10 Issue 6, pn/a-N.PAG, 14p
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