Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Holste, Dirk"'
Alternative pre-messenger RNA splicing affects a majority of human genes and plays important roles in development and disease. Alternative splicing (AS) events conserved since the divergence of human and mouse are likely of primary biological importa
Externí odkaz:
http://hdl.handle.net/1721.1/30411
Autor:
Li, Wentian, Holste, Dirk
Publikováno v:
Physical Review E, 71, 041910 (2005)
Spatial fluctuations of guanine and cytosine base content (GC%) are studied by spectral analysis for the complete set of human genomic DNA sequences. We find that (i) the 1/f^alpha decay is universally observed in the power spectra of all twenty-four
Externí odkaz:
http://arxiv.org/abs/q-bio/0411016
Autor:
Li, Wentian, Holste, Dirk
Publikováno v:
Computational Biology and Chemistry, 28(5-6): 393-399 (2004)
An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21. This oscillation is localized in the rightmost one-eighth region of the chromosome, from 43.5 Mb to 46.5 Mb. F
Externí odkaz:
http://arxiv.org/abs/q-bio/0411015
Autor:
Li, Wentian, Holste, Dirk
Publikováno v:
Fluctuation and Noise Letters, 4(3):L453-L464 (2004)
We study global fluctuations of the guanine and cytosine base content (GC%) in mouse genomic DNA using spectral analyses. Power spectra S(f) of GC% fluctuations in all nineteen autosomal and two sex chromosomes are observed to have the universal func
Externí odkaz:
http://arxiv.org/abs/q-bio/0411017
Autor:
Yeo, Gene W., Van Nostrand, Eric, Holste, Dirk, Poggio, Tomaso, Burge, Christopher B., Sharp, Phillip A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 Feb . 102(8), 2850-2855.
Externí odkaz:
https://www.jstor.org/stable/3374710
Publikováno v:
foresight, 2012, Vol. 14, Issue 1, pp. 41-55.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/14636681211210350
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 202 (2008)
Abstract Background The splicing of pre-mRNAs is conspicuously often variable and produces multiple alternatively spliced (AS) isoforms that encode different messages from one gene locus. Computational studies uncovered a class of highly similar isof
Externí odkaz:
https://doaj.org/article/b6e3b128584142a0ac36cad778970231
Autor:
Holste, Dirk1 uwe.ohler@duke.edu, Ohler, Uwe2
Publikováno v:
PLoS Computational Biology. Jan2008, Vol. 4 Issue 1, pe21. 10p. 4 Diagrams.
Autor:
Fairbrother, William G.1,2, Holste, Dirk2, Burge, Christopher B.2 cburge@mit.edu(CBB), Sharp, Phillip A.1,2,3 sharppa@mit.edu(PAS)
Publikováno v:
PLoS Biology. Sep2004, Vol. 2 Issue 9, p1388-1395. 8p.
Publikováno v:
Fluctuation & Noise Letters. Sep2004, Vol. 4 Issue 3, pL453-L464. 12p. 1 Chart, 2 Graphs.