Total Sleep Deprivation Increases Brain Age Prediction Reversibly in Multisite Samples of Young Healthy Adults.

Autor: Chu C; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany.; State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China., Holst SC; Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark.; Institute of Pharmacology and Toxicology, University of Zurich, CH-8006 Zurich, Switzerland., Elmenhorst EM; Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany.; Institute for Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany., Foerges AL; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany.; Department of Neurophysiology, Institute of Zoology (Bio-II), RWTH Aachen University, 52074 Aachen, Germany., Li C; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany., Lange D; Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany., Hennecke E; Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany., Baur DM; Institute of Pharmacology and Toxicology, University of Zurich, CH-8006 Zurich, Switzerland., Beer S; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany., Hoffstaedter F; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Institute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Forschungszentrum Jülich, 52428 Jülich, Germany., Knudsen GM; Neurobiology Research Unit, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark.; Institute of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark., Aeschbach D; Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center, 51147 Cologne, Germany.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts 02115.; Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts 02115.; Institute of Experimental Epileptology and Cognition Research, Faculty of Medicine, University of Bonn, 53127, Bonn, Germany., Bauer A; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany.; Neurological Department, Medical Faculty, Heinrich-Heine-University, 40225 Düsseldorf, Germany., Landolt HP; Institute of Pharmacology and Toxicology, University of Zurich, CH-8006 Zurich, Switzerland.; Sleep & Health Zurich, University Center of Competence, University of Zurich, Zurich, Switzerland., Elmenhorst D; Institute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52428 Jülich, Germany d.elmenhorst@fz-juelich.de.; Department of Nuclear Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.; Division of Medical Psychology, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, 53127 Germany.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2023 Mar 22; Vol. 43 (12), pp. 2168-2177. Date of Electronic Publication: 2023 Feb 20.

Exploring cognitive and biological correlates of sleep quality and their potential links with Alzheimer's disease (ALFASleep project): protocol for an observational study.

Autor: Fauria K; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain., Minguillon C; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Knezevic I; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain., Tort-Colet N; Barcelonaβeta Brain Research Center, Barcelona, Spain., Stankeviciute L; Barcelonaβeta Brain Research Center, Barcelona, Spain., Hernández L; Barcelonaβeta Brain Research Center, Barcelona, Spain., Rădoi A; Barcelonaβeta Brain Research Center, Barcelona, Spain., Deulofeu C; Barcelonaβeta Brain Research Center, Barcelona, Spain., Fuentes-Julián S; Barcelonaβeta Brain Research Center, Barcelona, Spain., Turull I; Barcelonaβeta Brain Research Center, Barcelona, Spain., Fusté D; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Pasqual Maragall Foundation, Barcelona, Spain., Sánchez-Benavides G; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Arenaza-Urquijo EM; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Suárez-Calvet M; Barcelonaβeta Brain Research Center, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Servei de Neurologia, Hospital del Mar, Barcelona, Spain., Holst SC; F Hoffmann-La Roche, Basel, Switzerland., Garcés P; F Hoffmann-La Roche, Basel, Switzerland., Mueggler T; F Hoffmann-La Roche, Basel, Switzerland., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Hong Kong, People's Republic of China., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Arqueros A; Neurology Service, Hospital Clínic de Barcelona and Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Iranzo Á; Neurology Service, Hospital Clínic de Barcelona and Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Domingo Gispert J; Barcelonaβeta Brain Research Center, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, Madrid, Spain., Molinuevo JL; Barcelonaβeta Brain Research Center, Barcelona, Spain., Grau-Rivera O; Barcelonaβeta Brain Research Center, Barcelona, Spain ograu@barcelonabeta.org.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Salud Carlos III, Madrid, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Servei de Neurologia, Hospital del Mar, Barcelona, Spain.

Publikováno v: BMJ open [BMJ Open] 2022 Dec 30; Vol. 12 (12), pp. e067159. Date of Electronic Publication: 2022 Dec 30.

The glymphatic system: Current understanding and modeling.

Autor: Bohr T; Department of Physics, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark., Hjorth PG; Department of Applied Mathematics and Computer Science, Technical University of Denmark, Richard Petersens Plads, 2800 Kgs. Lyngby, Denmark., Holst SC; Neuroscience and Rare Diseases Discovery and Translational Area, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Grenzacherstrasse 124, 4070 Basel, Switzerland., Hrabětová S; Department of Cell Biology and The Robert Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, NY, USA., Kiviniemi V; Oulu Functional NeuroImaging, Department of Diagnostic Radiology, MRC, Oulu University Hospital, Oulu, Finland.; Medical Imaging, Physics and Technology, the Faculty of Medicine, University of Oulu, Oulu, Finland., Lilius T; Department of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Emergency Medicine and Services, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Lundgaard I; Department of Experimental Medical Science, Lund University, Lund, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden., Mardal KA; Department of Mathematics, University of Oslo, Oslo, Norway.; Simula Research Laboratory, Department of Numerical Analysis and Scientific Computing, Oslo, Norway., Martens EA; Centre for Mathematical Sciences, Lund University, Sweden., Mori Y; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nägerl UV; Instítut Interdisciplinaire de Neurosciences, Université de Bordeaux / CNRS UMR 5297, Centre Broca Nouvelle-Aquitaine, 146 rue Léo Saignat, CS 61292 Case 130, 33076 Bordeaux Cedex France., Nicholson C; Department of Neuroscience and Physiology, New York University Grossman School of Medicine, New York, NY, USA.; Department of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA., Tannenbaum A; Departments of Computer Science/ Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, USA., Thomas JH; Department of Mechanical Engineering, University of Rochester, Rochester, 14627 NY, USA., Tithof J; Department of Mechanical Engineering, University of Minnesota, Minneapolis, USA., Benveniste H; Department of Anesthesiology, Yale School of Medicine, New Haven, CT, USA.; Department of Biomedical Engineering, Yale School of Medicine, New Haven, CT, USA., Iliff JJ; VISN 20 Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.; Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA., Kelley DH; Department of Mechanical Engineering, University of Rochester, Rochester, 14627 NY, USA., Nedergaard M; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, 14642 NY, USA.

Publikováno v: IScience [iScience] 2022 Aug 20; Vol. 25 (9), pp. 104987. Date of Electronic Publication: 2022 Aug 20 (Print Publication: 2022).

Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations.

Autor: Helakari H; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland vesa.kiviniemi@oulu.fi heta.helakari@oulu.fi.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Korhonen V; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Holst SC; Neurobiology Research Unit, University of Copenhagen, 2200 Copenhagen, Denmark., Piispala J; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland.; Clinical Neurophysiology, Oulu University Hospital, 90220 Oulu, Finland., Kallio M; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland.; Clinical Neurophysiology, Oulu University Hospital, 90220 Oulu, Finland., Väyrynen T; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Huotari N; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Raitamaa L; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Tuunanen J; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Kananen J; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Järvelä M; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Tuovinen T; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Raatikainen V; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Borchardt V; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland., Kinnunen H; Oura Health, 90590 Oulu, Finland., Nedergaard M; Center of Translational Neuromedicine, University of Copenhagen, 2200 Copenhagen, Denmark.; Center of Translational Neuromedicine, University of Rochester, Rochester, New York 14642., Kiviniemi V; Oulu Functional Neuroimaging, Department of Diagnostic Radiology, Oulu University Hospital, 90220 Oulu, Finland vesa.kiviniemi@oulu.fi heta.helakari@oulu.fi.; Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90220 Oulu, Finland.; Medical Research Center, Oulu University Hospital, 90220 Oulu, Finland.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Mar 23; Vol. 42 (12), pp. 2503-2515. Date of Electronic Publication: 2022 Feb 08.

Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep.

Autor: Ulv Larsen SM; Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Landolt HP; Institute of Pharmacology & Toxicology, University of Zurich, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University and ETH Zurich, Zurich, Switzerland.; Sleep & Health Zurich, University Center of Competence, Zurich, Switzerland., Berger W; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University and ETH Zurich, Zurich, Switzerland.; Institute of Medical Molecular Genetics, University of Zurich, Schlieren, Switzerland., Nedergaard M; Center for Translational Neuromedicine, University of Copenhagen, Copenhagen, Denmark., Knudsen GM; Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Holst SC; Neurobiology Research Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Sleep & Health Zurich, University Center of Competence, Zurich, Switzerland.

Publikováno v: PLoS biology [PLoS Biol] 2020 May 05; Vol. 18 (5), pp. e3000623. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020).