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Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature
Autor:
Daste, F, Walrant, A, Holst, MR, Gadsby, Mason, J, Lee, J, Brook, D, Lee, S, Mettlen, M, Larsson, E, Lundmark, R, Gallop, JL
The conditional use of actin during clathrin-mediated endocytosis in mammalian cells suggests that the cell controls whether and how actin is used. Using a combination of biochemical reconstitution and mammalian cell culture, we elucidate a mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4715968b45bad4b858d7628f553e924
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Autor:
Holst MR; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark., Richner M; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark., Arenshøj PO; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark., Alam P; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark.; Laboratory of Neurological Infection and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, 59840, USA., Hyldig K; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark.; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, Copenhagen, 2500, Denmark., Nielsen MS; Department of Biomedicine, Aarhus University, Aarhus C, 8000, Denmark. mn@biomed.au.dk.
Publikováno v:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 Oct 14; Vol. 21 (1), pp. 80. Date of Electronic Publication: 2024 Oct 14.
Autor:
Ozgür B; Department of Pharmacy, University of Copenhagen, Universitetsparken 2, Copenhagen, DK-2100, Denmark.; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, DK-2500, Denmark., Puris E; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany., Brachner A; AIT - Austrian Institute of Technology GmbH, Vienna, 1210, Austria., Appelt-Menzel A; Chair Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, 97070, Würzburg, Germany.; Fraunhofer Institute for Silicate Research ISC, Translational Center Regenerative Therapies (TLC-RT) Röntgenring 11, 97070, Würzburg, Germany., Oerter S; Chair Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, 97070, Würzburg, Germany.; Fraunhofer Institute for Silicate Research ISC, Translational Center Regenerative Therapies (TLC-RT) Röntgenring 11, 97070, Würzburg, Germany., Balzer V; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany., Holst MR; Department of Biomedicine, Aarhus University, Aarhus, DK-8000, Denmark., Christiansen RF; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, DK-2500, Denmark., Hyldig K; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, DK-2500, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, DK-8000, Denmark., Buckley ST; Global Research Technologies, Novo Nordisk A/S, Måløv, DK-2760, Denmark., Kristensen M; Department of Pharmacy, University of Copenhagen, Universitetsparken 2, Copenhagen, DK-2100, Denmark., Auriola S; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Jensen A; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, DK-2500, Denmark., Fricker G; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany., Nielsen MS; Department of Biomedicine, Aarhus University, Aarhus, DK-8000, Denmark., Neuhaus W; AIT - Austrian Institute of Technology GmbH, Vienna, 1210, Austria.; Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Krems, 3500, Austria., Brodin B; Department of Pharmacy, University of Copenhagen, Universitetsparken 2, Copenhagen, DK-2100, Denmark. birger.brodin@sund.ku.dk.
Publikováno v:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Dec 19; Vol. 20 (1), pp. 96. Date of Electronic Publication: 2023 Dec 19.
Autor:
Holst MR; Department of Biomedicine, Aarhus University, Aarhus, Denmark., de Wit NM; Department of Molecular Cell Biology and Immunology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Amsterdam, The Netherlands., Ozgür B; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, 2500, Copenhagen, Denmark., Brachner A; AIT Austrian Institute of Technology GmbH, Competence Unit Molecular Diagnostics, Centre for Health and Bioresources, Vienna, Austria., Hyldig K; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, 2500, Copenhagen, Denmark., Appelt-Menzel A; Chair Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, Röntgenring 11, Würzburg, Germany.; Translational Center Regenerative Therapies (TLC-RT), Fraunhofer Institute for Silicate Research ISC, Röntgenring 12, Würzburg, Germany., Sleven H; Translational Molecular Neuroscience Group, University of Oxford, Oxford, UK., Cader Z; Translational Molecular Neuroscience Group, University of Oxford, Oxford, UK., de Vries HE; Department of Molecular Cell Biology and Immunology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Amsterdam, The Netherlands., Neuhaus W; AIT Austrian Institute of Technology GmbH, Competence Unit Molecular Diagnostics, Centre for Health and Bioresources, Vienna, Austria.; Department of Medicine, Faculty Medicine and Dentistry, Private Danube University, 3500, Krems, Austria., Jensen A; Biotherapeutic Discovery, H. Lundbeck A/S, Valby, 2500, Copenhagen, Denmark., Brodin B; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Nielsen MS; Department of Biomedicine, Aarhus University, Aarhus, Denmark. mn@biomed.au.dk.
Publikováno v:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Nov 06; Vol. 20 (1), pp. 82. Date of Electronic Publication: 2023 Nov 06.
Autor:
Nielsen SSE; Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus C, 8000, Denmark., Holst MR; Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus C, 8000, Denmark., Langthaler K; CNS Drug Delivery and Barrier Modelling, University of Copenhagen, Copenhagen, Denmark.; Translational DMPK, H. Lundbeck A/S, Copenhagen, Denmark., Christensen SC; Pathology & Imaging, Novo Nordisk, Måløv, Denmark., Bruun EH; Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus C, 8000, Denmark., Brodin B; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2100, Denmark., Nielsen MS; Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus C, 8000, Denmark. mn@biomed.au.dk.
Publikováno v:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Jun 19; Vol. 20 (1), pp. 48. Date of Electronic Publication: 2023 Jun 19.