Výsledky vyhledávání - "Holmes, M. C."

Akademický článek

Targeted Gene Addition into a Specified Location in the Human Genome Using Designed Zinc Finger Nucleases

Autor: Moehle, E. A., Rock, J. M., Lee, Y. L., Jouvenot, Y., DeKelver, R. C., Gregory, P. D., Urnov, F. D., Holmes, M. C.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2007 Feb . 104(9), 3055-3060.

Externí odkaz: https://www.jstor.org/stable/25426603

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Akademický článek

Modulation of Oestrogen Receptor-β mRNA Expression in Rat Paraventricular and Supraoptic Nucleus Neurones Following Adrenal Steroid Manipulation and Hyperosmotic Stimulation.

Autor: Somponpun, S. J.^1,2, Holmes, M. C.², Seckl, J. R.², Russell, J. A.¹ j.a.russell@ed.ac.uk

Publikováno v: Journal of Neuroendocrinology. May2004, Vol. 16 Issue 5, p472-482. 11p.

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Akademický článek

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Forebrain-specific transgene rescue of 11β-HSD1 associates with impaired spatial memory and reduced hippocampal BDNF mRNA levels in aged 11β-HSD1 deficient mice

Autor: Caughey, S., Harris, A. P., Seckl, J. R., Holmes, M. C., Yau, J. L. W.

Publikováno v: Caughey, S, Harris, A P, Seckl, J R, Holmes, M C & Yau, J L W 2016, ' Forebrain-specific transgene rescue of 11β-HSD1 associates with impaired spatial memory and reduced hippocampal BDNF mRNA levels in aged 11β-HSD1 deficient mice ', Journal of Neuroendocrinology . https://doi.org/10.1111/jne.12447

Mice lacking the intracellular glucocorticoid-regenerating enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) are protected from age-related spatial memory deficits. 11β-HSD1 is expressed predominantly in brain, liver and adipose tissue. Re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::ec14165dde2aa82327abd73b9b5c1577
https://www.pure.ed.ac.uk/ws/files/29522342/Yau_J_Forebrain_specific....pdf

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Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish

Autor: Wilson, K.S., Tucker, Carl, Al-Dujaili, E.A.S., HOLMES, M C, Hadoke, Patrick, Kenyon, Christopher, Denvir, Martin

Publikováno v: Wilson, K S, Tucker, C, Al-Dujaili, E A S, HOLMES, M C, Hadoke, P, Kenyon, C & Denvir, M 2016, ' Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish ', Journal of Endocrinology . https://doi.org/10.1530/JOE-15-0376

Glucocorticoids (GCs) in utero influence embryonic development with consequent programmed effects on adult physiology and pathophysiology and altered susceptibility to cardiovascular disease. However, in viviparous species, studies of these processes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::2c455e0435f16d70ba2e3ae97c9ceb6e
https://hdl.handle.net/20.500.11820/54e1819b-33bd-4d1d-a882-39b6fd22a2f7

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