Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry

Autor: Mueller, Stefanie H, Lai, Alvina G, Valkovskaya, Maria, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Lush, Michael, Abu-Ful, Zomoruda, Ahearn, Thomas U, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Arndt, Volker, Aronson, Kristan J, Augustinsson, Annelie, Baert, Thais, Freeman, Laura E Beane, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V, Bojesen, Stig E, Bonanni, Bernardo, Brenner, Hermann, Brucker, Sara Y, Buys, Saundra S, Castelao, Jose E, Chan, Tsun L, Chang-Claude, Jenny, Chanock, Stephen J, Choi, Ji-Yeob, Chung, Wendy K, Sahlberg, Kristine K, Børresen-Dale, Anne-Lise, Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Sauer, Toril, Haakensen, Vilde, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecile E, Reinertsen, Kristin V, Helland, Åslaug, Riis, Margit, Geisler, Jürgen, Grenaker Alnaes, Grethe I, Colonna, Sarah V, Cornelissen, Sten, Couch, Fergus J, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dörk, Thilo, Dossus, Laure, Dwek, Miriam, Eccles, Diana M, Ekici, Arif B, Eliassen, A Heather, Engel, Christoph, Evans, D Gareth, Fasching, Peter A, Fletcher, Olivia, Flyger, Henrik, Gago-Dominguez, Manuela, Gao, Yu-Tang, García-Closas, Montserrat, García-Sáenz, José A, Genkinger, Jeanine, Gentry-Maharaj, Aleksandra, Grassmann, Felix, Guénel, Pascal, Gündert, Melanie, Haeberle, Lothar, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Harkness, Elaine F, Harrington, Patricia A, Hartikainen, Jaana M, Hartman, Mikael, Hein, Alexander, Ho, Weang-Kee, Hooning, Maartje J, Hoppe, Reiner, Hopper, John L, Houlston, Richard S, Howell, Anthony, Hunter, David J, Huo, Dezheng, Marsh, Deborah, Scott, Rodney, Baxter, Robert, Yip, Desmond, Carpenter, Jane, Davis, Alison, Pathmanathan, Nirmala, Simpson, Peter, Graham, Dinny, Sachchithananthan, Mythily, Ito, Hidemi, Iwasaki, Motoki, Jakubowska, Anna, Janni, Wolfgang, John, Esther M, Jones, Michael E, Jung, Audrey, Kaaks, Rudolf, Kang, Daehee, Khusnutdinova, Elza K, Kim, Sung-Won, Kitahara, Cari M, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N, Kubelka-Sabit, Katerina, Kurian, Allison W, Kwong, Ava, Lacey, James V, Lambrechts, Diether, Le Marchand, Loic, Li, Jingmei, Linet, Martha, Lo, Wing-Yee, Long, Jirong, Lophatananon, Artitaya, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Matsuo, Keitaro, Mavroudis, Dimitrios, Menon, Usha, Muir, Kenneth, Murphy, Rachel A, Nevanlinna, Heli, Newman, William G, Niederacher, Dieter, O’Brien, Katie M, Obi, Nadia, Offit, Kenneth, Olopade, Olufunmilayo I, Olshan, Andrew F, Olsson, Håkan, Park, Sue K, Patel, Alpa V, Patel, Achal, Perou, Charles M, Peto, Julian, Pharoah, Paul DP, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rack, Brigitte, Radice, Paolo, Ramachandran, Dhanya, Rashid, Muhammad U, Rennert, Gad, Romero, Atocha, Ruddy, Kathryn J, Ruebner, Matthias, Saloustros, Emmanouil, Sandler, Dale P, Sawyer, Elinor J, Schmidt, Marjanka K, Schmutzler, Rita K, Schneider, Michael O, Scott, Christopher, Shah, Mitul, Sharma, Priyanka, Shen, Chen-Yang, Shu, Xiao-Ou, Simard, Jacques, Surowy, Harald, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Teo, Soo Hwang, Teras, Lauren R, Toland, Amanda E, Tollenaar, Rob AEM, Torres, Diana, Torres-Mejía, Gabriela, Troester, Melissa A, Truong, Thérèse, Vachon, Celine M, Vijai, Joseph, Weinberg, Clarice R, Wendt, Camilla, Winqvist, Robert, Wolk, Alicja, Wu, Anna H, Yamaji, Taiki, Yang, Xiaohong R, Yu, Jyh-Cherng, Zheng, Wei, Ziogas, Argyrios, Ziv, Elad, Dunning, Alison M, Easton, Douglas F, Hemingway, Harry, Hamann, Ute, Kuchenbaecker, Karoline B

Publikováno v: NBCS Collaborators, Mueller, S H, Lai, A G, Valkovskaya, M, Michailidou, K, Bolla, M K, Wang, Q, Dennis, J, Lush, M, Abu-Ful, Z, Ahearn, T U, Andrulis, I L, Anton-Culver, H, Antonenkova, N N, Arndt, V, Aronson, K J, Augustinsson, A, Baert, T, Freeman, L E B, Beckmann, M W, Behrens, S, Benitez, J, Bermisheva, M, Blomqvist, C, Bogdanova, N V, Bojesen, S E, Bonanni, B, Brenner, H, Brucker, S Y, Buys, S S, Castelao, J E, Chan, T L, Chang-Claude, J, Chanock, S J, Choi, J-Y, Chung, W K, Colonna, S V, Cornelissen, S, Couch, F J, Evans, D G, Harkness, E F, Howell, A, Jones, M E, Lo, W-Y, Lophatananon, A, Muir, K, Newman, W G, Patel, A V, Scott, C, Shen, C-Y & Zheng, W 2023, ' Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry ', Genome Medicine, vol. 15, no. 1, 7, pp. 7 . https://doi.org/10.1186/s13073-022-01152-5
Genome Medicine, 15(1):7. BioMed Central Ltd.

Background Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes. Methods We evaluated the potential of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bf1402280d114c73d412955bab3932

Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases

Autor: Figlioli, Gisella, Billaud, Amandine, Wang, Qin, Bolla, Manjeet K., Dennis, Joe, Lush, Michael, Kvist, Anders, Adank, Muriel A., Ahearn, Thomas U., Antonenkova, Natalia N., Auvinen, Päivi, Behrens, Sabine, Bermisheva, Marina, Bogdanova, Natalia V., Bojesen, Stig E., Bonanni, Bernardo, Brüning, Thomas, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Cessna, Melissa H., Sahlberg, Guro Kristine Kleivi, Børresen-Dale, Anne-Lise, Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Haakensen, Vilde Drageset, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecilie E., Reinertsen, Kristin Valborg, Helland, Åslaug, Riis, Margit, Geisler, Jürgen, OSBREAC, Oslo Breast Cancer Consortium, Grenaker, Grethe Irene, Czene, Kamila, Devilee, Peter, Eriksson, Mikael, Dörk, Thilo, Fasching, Peter A., Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, Glendon, Gord, Gómez Garcia, Encarna B., González-Neira, Anna, Grassmann, Felix, Guénel, Pascal, Hahnen, Eric, Hamann, Ute, Hillemanns, Peter, Hooning, Maartje J., Hoppe, Reiner, Howell, Anthony, Humphreys, Keith, Jakubowska, Anna, Khusnutdinova, Elza K., Kristensen, Vessela N., Lindblom, Annika, Loizidou, Maria A., Lubiński, Jan, Mannermaa, Arto, Maurer, Tabea, Mavroudis, Dimitrios, Newman, William G., Obi, Nadia, Panayiotidis, Mihalis I., Radice, Paolo, Rashid, Muhammad U., Rhenius, Valerie, Ruebner, Matthias, Sawyer, Elinor J., Saloustros, Emmanouil, Schmidt, Marjanka K., Schmutzler, Rita K., Shah, Mitul, Southey, Melissa C., Tomlinson, Ian, Truong, Thérèse, van Veen, Elke M., Wendt, Camilla, Dunning, Alison M., Yang, Xiaohong R., Michailidou, Kyriaki, Pharoah, Paul D. P., Easton, Douglas F., Andrulis, Irene L., Evans, D. Gareth, Hollestelle, Antoinette, Chang-Claude, Jenny, Milne, Roger L., Peterlongo, Paolo

Publikováno v: Figlioli, Gisella Billaud, Amandine Wang, Qin Bolla, Manjeet K. Dennis, Joe Lush, Michael Kvist, Anders Adank, Muriel A. Ahearn, Thomas U. Antonenkova, Natalia N. Auvinen, Päivi Behrens, Sabine Bermisheva, Marina Bogdanova, Natalia V. Bojesen, Stig E. Bonanni, Bernardo Brüning, Thomas Camp, Nicola J. Campbell, Archie Castelao, Jose E. Cessna, Melissa H. Sahlberg, Guro Kristine Kleivi Børresen-Dale, Anne-Lise Ottestad, Lars Kåresen, Rolf Schlichting, Ellen Holmen, Marit Muri Haakensen, Vilde Drageset Engebråten, Olav Naume, Bjørn Fosså, Alexander Kiserud, Cecilie E. Reinertsen, Kristin Valborg Helland, Åslaug Riis, Margit Geisler, Jürgen OSBREAC, Oslo Breast Cancer Consortium Grenaker, Grethe Irene Czene, Kamila Devilee, Peter Eriksson, Mikael Dörk, Thilo Fasching, Peter A. Flyger, Henrik Gabrielson, Marike Gago-Dominguez, Manuela García-Closas, Montserrat Glendon, Gord Gómez Garcia, Encarna B. González-Neira, Anna Grassmann, Felix Guénel, Pascal Hahnen, Eric Hamann, Ute Hillemanns, Peter Hooning, Maartje J. Hoppe, Reiner Howell, Anthony Humphreys, Keith Jakubowska, Anna Khusnutdinova, Elza K. Kristensen, Vessela N. Lindblom, Annika Loizidou, Maria A. Lubiński, Jan Mannermaa, Arto Maurer, Tabea Mavroudis, Dimitrios Newman, William G. Obi, Nadia Panayiotidis, Mihalis I. Radice, Paolo Rashid, Muhammad U. Rhenius, Valerie Ruebner, Matthias Sawyer, Elinor J. Saloustros, Emmanouil Schmidt, Marjanka K. Schmutzler, Rita K. Shah, Mitul Southey, Melissa C. Tomlinson, Ian Truong, Thérèse van Veen, Elke M. Wendt, Camilla Dunning, Alison M. Yang, Xiaohong R. Michailidou, Kyriaki Pharoah, Paul D. P. Easton, Douglas F. Andrulis, Irene L. Evans, D. Gareth Hollestelle, Antoinette Chang-Claude, Jenny Milne, Roger L. Peterlongo, Paolo . Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases. Cancers. 2023, 15(13)
Cancers

Externí odkaz: http://hdl.handle.net/10852/110073

CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

Autor: Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Burwinkel, Barbara, Campa, Daniele, Canzian, Federico, Castelao, Jose E., Chanock, Stephen J., Chenevix-Trench, Georgia, Clarke, Christine L., Conroy, Don M., Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Dörk, Thilo, Eliassen, A. Heather, Engel, Christoph, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine, Floris, Giuseppe, Flyger, Henrik, Gago-Dominguez, Manuela, Gapstur, Susan M., García-Closas, Montserrat, Gaudet, Mia M., Giles, Graham G., Goldberg, Mark S., González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A., Håkansson, Niclas, Hall, Per, Hamann, Ute, Harrington, Patricia A., Hart, Steven N., Hooning, Maartje J., Hopper, John L., Howell, Anthony, Hunter, David J., Jager, Agnes, Jakubowska, Anna, John, Esther M., Kaaks, Rudolf, Keeman, Renske, Khusnutdinova, Elza, Kitahara, Cari M., Kosma, Veli-Matti, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N., Kurian, Allison W., Lambrechts, Diether, Le Marchand, Loic, Linet, Martha, Lubiński, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Martens, John W. M., Mavroudis, Dimitrios, Mayes, Rebecca, Meindl, Alfons, Milne, Roger L., Neuhausen, Susan L., Nevanlinna, Heli, Newman, William G., Nielsen, Sune F., Nordestgaard, Børge G., Obi, Nadia, Olshan, Andrew F., Olson, Janet E., Olsson, Håkan, Orban, Ester, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Rennert, Gad, Rennert, Hedy S., Ruddy, Kathryn J., Saloustros, Emmanouil, Sandler, Dale P., Sawyer, Elinor J., Schmutzler, Rita K., Scott, Christopher, Shu, Xiao-Ou, Simard, Jacques, Smichkoska, Snezhana, Sohn, Christof, Southey, Melissa C., Spinelli, John J., Stone, Jennifer, Tamimi, Rulla M., Taylor, Jack A., Tollenaar, Rob A. E. M., Tomlinson, Ian, Troester, Melissa A., Truong, Thérèse, Vachon, Celine M., van Veen, Elke M., Wang, Sophia S., Weinberg, Clarice R., Wendt, Camilla, Wildiers, Hans, Winqvist, Robert, Wolk, Alicja, Zheng, Wei, Ziogas, Argyrios, Dunning, Alison M., Pharoah, Paul D. P., Easton, Douglas F., Howie, A. Forbes, Peto, Julian, dos-Santos-Silva, Isabel, Swerdlow, Anthony J., Chang-Claude, Jenny, Schmidt, Marjanka K., Orr, Nick, Fletcher, Olivia, Børresen-Dale, Anne-Lise, Alnæs, Grethe I. Grenaker, Sahlberg, Kristine K., Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Sauer, Toril, Haakensen, Vilde, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecile E., Reinertsen, Kristin V., Helland, Åslaug, Riis, Margit, Geisler, Jürgen, Bowtell, David D. L., deFazio, Anna, Webb, Penelope M., Clarke, Christine, Marsh, Deborah, Scott, Rodney, Baxter, Robert, Yip, Desmond, Carpenter, Jane, Davis, Alison, Pathmanathan, Nirmala, Simpson, Peter, Graham, Dinny, Sachchithananthan, Mythily, Amor, David, Andrews, Lesley, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Bennett, Ian, Bogwitz, Michael, Botes, Leon, Brennan, Meagan, Brown, Melissa, Buckley, Michael, Burke, Jo, Butow, Phyllis, Caldon, Liz, Campbell, Ian, Chauhan, Deepa, Chauhan, Manisha, Christian, Alice, Cohen, Paul, Colley, Alison, Crook, Ashley, Cui, James, Cummings, Margaret, Dawson, Sarah-Jane, DeFazio, Anna, Delatycki, Martin, Dickson, Rebecca, Dixon, Joanne, Edkins, Ted, Edwards, Stacey, Farshid, Gelareh, Fellows, Andrew, Fenton, Georgina, Field, Michael, Flanagan, James, Fong, Peter, Forrest, Laura, Fox, Stephen, French, Juliet, Friedlander, Michael, Gaff, Clara, Gattas, Mike, George, Peter, Greening, Sian, Harris, Marion, Hart, Stewart, Hayward, Nick, Hopper, John, Hoskins, Cass, Hunt, Clare, James, Paul, Jenkins, Mark, Kidd, Alexa, Kirk, Judy, Koehler, Jessica, Kollias, James, Lakhani, Sunil, Lawrence, Mitchell, Lindeman, Geoff, Lipton, Lara, Lobb, Liz, Mann, Graham, McLachlan, Sue Anne, Meiser, Bettina, Milne, Roger, Nightingale, Sophie, O’Connell, Shona, O’Sullivan, Sarah, Ortega, David Gallego, Pachter, Nick, Patterson, Briony, Pearn, Amy, Phillips, Kelly, Pieper, Ellen, Rickard, Edwina, Robinson, Bridget, Saleh, Mona, Salisbury, Elizabeth, Saunders, Christobel, Saunus, Jodi, Scott, Clare, Sexton, Adrienne, Shelling, Andrew, Southey, Melissa, Spurdle, Amanda, Taylor, Jessica, Taylor, Renea, Thorne, Heather, Trainer, Alison, Tucker, Kathy, Visvader, Jane, Walker, Logan, Williams, Rachael, Winship, Ingrid, Young, Mary Ann

Publikováno v: NBCS Collaborators 2021, ' CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers ', British Journal of Cancer, vol. 124, no. 4, pp. 842-854 . https://doi.org/10.1038/s41416-020-01185-w
British Journal of Cancer
British Journal of Cancer, 124(4), 842-854. SPRINGERNATURE
Johnson, N, Maguire, S, Morra, A, Kapoor, P M, Tomczyk, K, Jones, M E, Schoemaker, M J, Gilham, C, Bolla, M K, Wang, Q, Dennis, J, Ahearn, T U, Andrulis, I L, Anton-culver, H, Antonenkova, N N, Arndt, V, Aronson, K J, Augustinsson, A, Baynes, C, Freeman, L E B, Beckmann, M W, Benitez, J, Bermisheva, M, Blomqvist, C, Boeckx, B, Bogdanova, N V, Bojesen, S E, Brauch, H, Brenner, H, Burwinkel, B, Campa, D, Canzian, F, Castelao, J E, Chanock, S J, Chenevix-trench, G, Clarke, C L, Conroy, D M, Couch, F J, Cox, A, Cross, S S, Czene, K, Dörk, T, Eliassen, A H, Engel, C, Evans, D G, Fasching, P A, Figueroa, J, Floris, G, Flyger, H, Gago-dominguez, M, Gapstur, S M, García-closas, M, Gaudet, M M, Giles, G G, Goldberg, M S, González-neira, A, Guénel, P, Hahnen, E, Haiman, C A, Håkansson, N, Hall, P, Hamann, U, Harrington, P A, Hart, S N, Hooning, M J, Hopper, J L, Howell, A, Hunter, D J, Jager, A, Jakubowska, A, John, E M, Kaaks, R, Keeman, R, Khusnutdinova, E, Kitahara, C M, Kosma, V, Koutros, S, Kraft, P, Kristensen, V N, Kurian, A W, Lambrechts, D, Le Marchand, L, Linet, M, Lubiński, J, Mannermaa, A, Manoukian, S, Margolin, S, Martens, J W M, Mavroudis, D, Mayes, R, Meindl, A, Milne, R L, Neuhausen, S L, Nevanlinna, H, Newman, W G, Nielsen, S F, Nordestgaard, B G, Obi, N, Olshan, A F, Olson, J E, Olsson, H, Orban, E, Park-simon, T, Peterlongo, P, Plaseska-karanfilska, D, Pylkäs, K, Rennert, G, Rennert, H S, Ruddy, K J, Saloustros, E, Sandler, D P, Sawyer, E J, Schmutzler, R K, Scott, C, Shu, X, Simard, J, Smichkoska, S, Sohn, C, Southey, M C, Spinelli, J J, Stone, J, Tamimi, R M, Taylor, J A, Tollenaar, R A E M, Tomlinson, I, Troester, M A, Truong, T, Vachon, C M, Van Veen, E M, Wang, S S, Weinberg, C R, Wendt, C, Wildiers, H, Winqvist, R, Wolk, A, Zheng, W, Ziogas, A, Dunning, A M, Pharoah, P D P, Easton, D F, Howie, A F, Peto, J, Dos-santos-silva, I, Swerdlow, A J, Chang-claude, J, Schmidt, M K, Orr, N & Fletcher, O 2021, ' CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers ', British Journal of Cancer . https://doi.org/10.1038/s41416-020-01185-w
British Journal of Cancer, 124(4), 842-854. Nature Publishing Group
Johnson, N, Maguire, S, Morra, A, Kapoor, P M, Tomczyk, K, Jones, M E, Schoemaker, M J, Gilham, C, Bolla, M K, Wang, Q, Dennis, J, Ahearn, T U, Andrulis, I L, Anton-Culver, H, Antonenkova, N N, Arndt, V, Aronson, K J, Augustinsson, A, Baynes, C, Freeman, L E B, Beckmann, M W, Benitez, J, Bermisheva, M, Blomqvist, C, Boeckx, B, Bogdanova, N V, Bojesen, S E, Brauch, H, Brenner, H, Burwinkel, B, Campa, D, Canzian, F, Castelao, J E, Chanock, S J, Chenevix-Trench, G, Clarke, C L, Børresen-Dale, A L, Alnæs, G I G, Sahlberg, K K, Ottestad, L, Kåresen, R, Schlichting, E, Holmen, M M, Sauer, T, Haakensen, V, Riis, M, Flyger, H, Nielsen, S F, Nordestgaard, B G, Scott, C, NBCS Collaborators, AOCS Group, ABCTB Investigators & kConFab Investigators 2021, ' CYP3A7*1C allele : linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers ', British Journal of Cancer, vol. 124, no. 4, pp. 842-854 . https://doi.org/10.1038/s41416-020-01185-w

Background Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary sex-hormone levels and brea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c80976e607f7f5adac25ce2443816d
https://pure.qub.ac.uk/en/publications/63fe40f3-a1a4-4f39-891d-c488d88096e8

Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?

Autor: Park, JooYong, Choi, Ji-Yeob, Choi, Jaesung, Chung, Seokang, Song, Nan, Park, Sue K, Han, Wonshik, Noh, Dong-Young, Ahn, Sei-Hyun, Lee, Jong Won, Kim, Mi Kyung, Jee, Sun Ha, Wen, Wanquing, Bolla, Manjeet K, Wang, Qing, Dennis, Joe, Michailido, Kyriaki, Shah, Mitul, Conroy, Don M., Harrington, Patricia A, Mayes, Rebecca, Czene, Kamila, Hall, Per, Teras, Lauren R, Patel, Alpa V, Couch, Fergus J, Olson, Janet E, Sawyer, Elinor J, Roylance, Rebecca, Bojesen, Stig E, Flyger, Henrik, Lambrechts, Deither, Baten, Adlina, Kristensen, Vessela N., Sahlberg, Kristine Kleivi, Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Sauer, Torill, Haakensen, Vilde Drageset, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecilie E., Reinertsen, Kristin Valborg, Helland, Åslaug, Riis, Margit, Geisler, Jürgen, Alnæs, Grethe Irene Grenaker

Publikováno v: Park, JooYong Choi, Ji-Yeob Choi, Jaesung Chung, Seokang Song, Nan Park, Sue K Han, Wonshik Noh, Dong-Young Ahn, Sei-Hyun Lee, Jong Won Kim, Mi Kyung Jee, Sun Ha Wen, Wanquing Bolla, Manjeet K Wang, Qing Dennis, Joe Michailido, Kyriaki Shah, Mitul Conroy, Don M. Harrington, Patricia A Mayes, Rebecca Czene, Kamila Hall, Per Teras, Lauren R Patel, Alpa V Couch, Fergus J Olson, Janet E Sawyer, Elinor J Roylance, Rebecca Bojesen, Stig E Flyger, Henrik Lambrechts, Deither Baten, Adlina Kristensen, Vessela N. Sahlberg, Kristine Kleivi Ottestad, Lars Kåresen, Rolf Schlichting, Ellen Holmen, Marit Muri Sauer, Torill Haakensen, Vilde Drageset Engebråten, Olav Naume, Bjørn Fosså, Alexander Kiserud, Cecilie E. Reinertsen, Kristin Valborg Helland, Åslaug Riis, Margit Geisler, Jürgen Alnæs, Grethe Irene Grenaker . Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?. Cancers. 2021, 13:2370(10), 1-21
Cancers

Externí odkaz: http://hdl.handle.net/10852/92741
https://www.duo.uio.no/bitstream/handle/10852/92741/1/Postnr%2B2000501_Park%2Bet%2Bal_cancers-13-02370%2B%25281%2529.pdf

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk

Autor: Liu, Jingjing, Prager - van der Smissen, Wendy J. C., Collée, J. Margriet, Bolla, Manjeet K., Wang, Qin, Michailidou, Kyriaki, Dennis, Joe, Ahearn, Thomas U., Aittomäki, Kristiina, Ambrosone, Christine B., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Arnold, Norbert, Aronson, Kristan J., Augustinsson, Annelie, Auvinen, Päivi, Becher, Heiko, Beckmann, Matthias W., Behrens, Sabine, Bermisheva, Marina, Bernstein, Leslie, Bogdanova, Natalia V., Bogdanova-Markov, Nadja, Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Briceno, Ignacio, Brucker, Sara Y., Brüning, Thomas, Burwinkel, Barbara, Cai, Qiuyin, Cai, Hui, Campa, Daniele, Canzian, Federico, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Choi, Ji-Yeob, Christiaens, Melissa, Clarke, Christine L., Couch, Fergus J., Czene, Kamila, Daly, Mary B., Devilee, Peter, dos-Santos-Silva, Isabel, Dwek, Miriam, Eccles, Diana M., Eliassen, A. Heather, Fasching, Peter A., Figueroa, Jonine, Flyger, Henrik, Fritschi, Lin, Gago-Dominguez, Manuela, Gapstur, Susan M., García-Closas, Montserrat, García-Sáenz, José A., Gaudet, Mia M., Giles, Graham G., Goldberg, Mark S., Goldgar, David E., Guénel, Pascal, Haiman, Christopher A., Håkansson, Niclas, Hall, Per, Harrington, Patricia A., Hart, Steven N., Hartman, Mikael, Hillemanns, Peter, Hopper, John L., Hou, Ming-Feng, Hunter, David J., Huo, Dezheng, Ito, Hidemi, Iwasaki, Motoki, Jakimovska, Milena, Jakubowska, Anna, John, Esther M., Kaaks, Rudolf, Kang, Daehee, Keeman, Renske, Khusnutdinova, Elza, Kim, Sung-Won, Kraft, Peter, Kristensen, Vessela N., Kurian, Allison W., Le Marchand, Loic, Li, Jingmei, Lindblom, Annika, Lophatananon, Artitaya, Luben, Robert N., Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Mariapun, Shivaani, Matsuo, Keitaro, Maurer, Tabea, Mavroudis, Dimitrios, Meindl, Alfons, Menon, Usha, Milne, Roger L., Muir, Kenneth, Mulligan, Anna Marie, Neuhausen, Susan L., Nevanlinna, Heli, Offit, Kenneth, Olopade, Olufunmilayo I., Olson, Janet E., Olsson, Håkan, Orr, Nick, Park, Sue K., Peterlongo, Paolo, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rack, Brigitte, Rau-Murthy, Rohini, Rennert, Gad, Rennert, Hedy S., Rhenius, Valerie, Romero, Atocha, Ruebner, Matthias, Saloustros, Emmanouil, Schmutzler, Rita K., Schneeweiss, Andreas, Scott, Christopher, Shah, Mitul, Shen, Chen-Yang, Shu, Xiao-Ou, Simard, Jacques, Sohn, Christof, Southey, Melissa C., Spinelli, John J., Tamimi, Rulla M., Tapper, William J., Teo, Soo H., Terry, Mary Beth, Torres, Diana, Truong, Thérèse, Untch, Michael, Vachon, Celine M., van Asperen, Christi J., Wolk, Alicja, Yamaji, Taiki, Zheng, Wei, Ziogas, Argyrios, Ziv, Elad, Torres-Mejía, Gabriela, Dörk, Thilo, Swerdlow, Anthony J., Hamann, Ute, Schmidt, Marjanka K., Dunning, Alison M., Pharoah, Paul D. P., Easton, Douglas F., Hooning, Maartje J., Martens, John W. M., Hollestelle, Antoinette, Sahlberg, Kristine K., Børresen-Dale, Anne-Lise, Ottestad, Lars, Kåresen, Rolf, Schlichting, Ellen, Holmen, Marit Muri, Sauer, Toril, Haakensen, Vilde, Engebråten, Olav, Naume, Bjørn, Fosså, Alexander, Kiserud, Cecile E., Reinertsen, Kristin V., Helland, Åslaug, Riis, Margit, Geisler, Jürgen, Alnæs, Grethe I. Grenaker, Bathen, Tone F., Borgen, Elin, Fritzman, Britt, Garred, Øystein, Geitvik, Gry Aarum, Hofvind, Solveig, Langerød, Anita, Lingjærde, Ole Christian, Mælandsmo, Gunhild Mari, Russnes, Hege G, Skjerven, Helle Kristine, Sørlie, Therese, Clarke, Christine, Marsh, Deborah, Scott, Rodney, Baxter, Robert, Yip, Desmond, Carpenter, Jane, Davis, Alison, Pathmanathan, Nirmala, Simpson, Peter, Graham, Dinny, Sachchithananthan, Mythily

In breast cancer, high levels of homeobox protein Hox-B13 (HOXB13) have been associated with disease progression of ER-positive breast cancer patients and resistance to tamoxifen treatment. Since HOXB13 p.G84E is a prostate cancer risk allele, we eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::687da2d5b932af9d9eae6d059b93b6eb
https://www.repository.cam.ac.uk/handle/1810/323966