Výsledky vyhledávání

Akademický článek

Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis

Publikováno v: ACR Open Rheumatology, Vol 5, Iss 10, Pp 556-562 (2023)

Objective Lung disease (LD) is an increasingly recognized complication of systemic juvenile idiopathic arthritis (sJIA). As there are no currently available guidelines for pulmonary screening in sJIA, we sought to develop such an algorithm at our ins

Externí odkaz: https://doaj.org/article/15b14e6147304b96b058d1ea5eb9b5d1

Zobrazit plný text záznamu

Akademický článek

Type I interferon signature and cycling lymphocytes in macrophage activation syndrome

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)

BACKGROUND Macrophage activation syndrome (MAS) is a life-threatening complication of Still’s disease (SD) characterized by overt immune cell activation and cytokine storm. We aimed to further understand the immunologic landscape of SD and MAS.METH

Externí odkaz: https://doaj.org/article/81b3a17577a741b6be6230b306b10f60

Zobrazit plný text záznamu

Akademický článek

Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis

Publikováno v: Frontiers in Immunology, Vol 13 (2023)

T peripheral helper (Tph) cells, identified in the synovium of adults with seropositive rheumatoid arthritis, drive B cell maturation and antibody production in non-lymphoid tissues. We sought to determine if similarly dysregulated T cell-B cell inte

Externí odkaz: https://doaj.org/article/2e6fb3b7d8f946bf87162e8a9df346f1

Zobrazit plný text záznamu

Akademický článek

Dysregulation of the cGAS-STING Pathway in Monogenic Autoinflammation and Lupus

Autor: Holly Wobma, Daniel S. Shin, Janet Chou, Fatma Dedeoğlu

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

One of the oldest mechanisms of immune defense against pathogens is through detection of foreign DNA. Since human DNA is compartmentalized into the nucleus, its presence in the cytosol heralds a potential threat. The cGAS-STING pathway is one of the

Externí odkaz: https://doaj.org/article/239b24c12e1a484fb9082a113b73d7c1

Zobrazit plný text záznamu

Akademický článek

When Local Bone Pain Is Just the Tip of the Iceberg—A Case Report of Three Patients With Chronic Multifocal Recurrent Osteomyelitis and Some Red Flags to Help Make the Diagnosis

Autor: Holly Wobma, Diego Jaramillo, Lisa Imundo

Publikováno v: Frontiers in Pediatrics, Vol 7 (2019)

Chronic recurrent multifocal osteomyelitis (CRMO) is an uncommon cause of chronic inflammatory bone pain in children that can be disabling. Often, this diagnosis is considered only after a prolonged workup, leading to frustration for families and unn

Externí odkaz: https://doaj.org/article/333b4d4614af4f5c9d5154a807fd1fd5

Zobrazit plný text záznamu

Genetic diagnosis of immune dysregulation can lead to targeted therapy for interstitial lung disease: A case series and single center approach

Autor: Holly Wobma, Ryan Perkins, Lisa Bartnikas, Fatma Dedeoğlu, Janet Chou, Ruth Ann Vleugels, Mindy S. Lo, Erin Janssen, Lauren A. Henderson, Jennifer Whangbo, Sara O. Vargas, Martha Fishman, Katie A. Krone, Alicia Casey

Publikováno v: Pediatr Pulmonol

In recent years, a growing number of monogenic disorders have been described that are characterized by immune dysregulation. A subset of these "primary immune regulatory disorders" can cause severe interstitial lung disease, often recognized in late

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e34d678f85b026dec8b81416e9b3c17
https://doi.org/10.1002/ppul.25924

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání