Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Holly W. Randall"'
Publikováno v:
Toxicologic Pathology. 21:465-479
Morphologic lesions have received only limited attention as in vitro endpoints of toxicity. In the present work, "tissue" and cell morphology of control and toxicant-treated primary dissociated cerebrocortical cell cultures from fetal mice were exami
Publikováno v:
Toxicology and Applied Pharmacology. 106:311-326
Formaldehyde dehydrogenase (FDH) activity has been demonstrated biochemically in the olfactory and respiratory mucosae and in the liver of the rat, but the cellular localization of this enzyme has not been investigated. A histochemical procedure was
Autor:
Robert R. Maronpot, Thomas M. Monticello, J R Hotchkiss, Holly W. Randall, H R Brown, Kevin T. Morgan
Publikováno v:
Toxicologic pathology. 19(4 Pt 1)
Proliferative lesions in the rodent nasal cavity are reviewed; attempt was made to compare species affected, sex differences, strain differences, route of administration and tumor types occurring both spontaneously and after induction by different ch
Histochemical localization of aldehyde dehydrogenase in the respiratory tract of the Fischer-344 rat
Publikováno v:
Toxicology and Applied Pharmacology. 82:560-567
Acetaldehyde, a nasal carcinogen and respiratory tract irritant, is metabolized by aldehyde dehydrogenase. The localization of aldehyde dehydrogenase in individual cells of the nasal passages, trachea, and lungs of the Fischer-344 rat was determined
Publikováno v:
Stain technology. 63(6)
The nasal region is important for studies in inhalation toxicology but is difficult to prepare for histological examination, especially in species as large as primates. A method for the histologic preparation of undecalcified, complete transverse sec
Publikováno v:
The American journal of anatomy. 179(1)
The nasal passages are anatomically complex, and while there have been a number of descriptions of nasal structure in many species, there is very little information available on the distribution of enzymes in the nasal mucosa. In rodents, this delica
Publikováno v:
Toxicology and applied pharmacology. 88(2)
Inhalation exposure of rats and mice to glycol ether acetates and acrylate esters causes degeneration of the olfactory epithelium but not of the respiratory epithelium. Since these compounds are metabolized via carboxylesterase to acids that are toxi