Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Holly Soutter"'
Autor:
Ying Zhang, Anthony Keefe, Paolo Centrella, John Cuozzo, Holly Soutter, Daniel Resnicow, Sevan Habeshian, Matt Clark
Publikováno v:
Cancer Research. 83:5331-5331
Increasingly drug discovery programs require the development of orally available and cell permeable classes of drugs derived from the chemical space beyond Lipinski’s rule of 5 (bRO5). The chameleon-like physicochemical properties and differentiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90906f0fa2796ed6934bc0068c331a9
https://doi.org/10.1158/1538-7445.am2023-5331
https://doi.org/10.1158/1538-7445.am2023-5331
Autor:
Bryce K. Allen, Meghana M. Kulkarni, Brian Chamberlain, Timothy Dwight, Cheryl Koh, Ramya Samant, Finith Jernigan, Jamie Rice, Dazhi Tan, Stella Li, Kristen Marino, Huang Huang, Evan Chiswick, Bethany Tesar, Sam Sparks, Zhixiong Lin, T. Dwight McGee, István Kolossváry, Charles Lin, Sharon Shechter, Holly Soutter, Cecilia Bastos, Mohammed Taimi, Sujen Lai, Alicia Petrin, Tracy Kane, Steven Swann, Humphrey Gardner, Christopher Winter, Woody Sherman
The protein STING (stimulator of interferon genes) is a central regulator of the innate immune system and plays an important role in antitumor immunity by inducing the production of cytokines such as type I interferon (IFN). Activation of STING stems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007367283e6d03ce62189d7f16465731
https://doi.org/10.1101/2022.05.23.493001
https://doi.org/10.1101/2022.05.23.493001
Autor:
Mutlu, Merve, Schmidt, Isabel, Morrison, Andrew I., Goretzki, Benedikt, Freuler, Felix, Begue, Damien, Simic, Oliver, Pythoud, Nicolas, Ahrne, Erik, Kapps, Sandra, Roest, Susan, Bonenfant, Debora, Jeanpierre, Delphine, Tran, Thi-Thanh-Thao, Maher, Rob, An, Shaojian, Rietsch, Amandine, Nigsch, Florian, Hofmann, Andreas, Reece-Hoyes, John
Publikováno v:
Nature Communications; 5/29/2024, Vol. 15 Issue 1, p1-16, 16p
Autor:
Sam Sparks, Sharon Shechter, Meghana M. Kulkarni, Bethany Tesar, Holly H. Soutter, Woody Sherman, James M Rice, Ramya Samant, Zhixiong Lin, Marino Kristen A, Steven Swann, Dazhi Tan, Cecilia Bastos, Chamberlain Brian T, Huang Huang, Stella Li, Christopher Winter, Sujen Lai, Dwight Timothy A, Bryce K. Allen, Mohammed Taimi, Cheryl Koh
Publikováno v:
Molecular Cancer Therapeutics. 18:LB-A20
STING (Stimulator of Interferon Genes) is a master regulator of type I interferons and a key mediator of innate immunity. Activation of STING provides two critical anti-tumor responses – (1) The “spark” for initiating a robust innate immune res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3436981b15293fda76f7de8c89981960
https://doi.org/10.1158/1535-7163.targ-19-lb-a20
https://doi.org/10.1158/1535-7163.targ-19-lb-a20