Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Holly S. Hake"'
Publikováno v:
eLife, Vol 9 (2020)
The dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. Action potential firing of serotonin dorsal raphe neurons is driven via α1-adrenergic receptors (α1-AR) activati
Externí odkaz:
https://doaj.org/article/463104f2681c4d35bedabc965ca4decf
Publikováno v:
J Neurosci
Activity of dorsal raphe neurons is controlled by noradrenaline afferents. In this brain region, noradrenaline activates Gαq-coupled α1-adrenergic receptors (α1-AR), causing action potential (AP) firing and serotonin release.In vitro, electrical s
Autor:
Esteban C. Loetz, Benjamin N. Greenwood, Holly S. Hake, Anais Sanchez, River R. Wood, Erik B. Oleson, Jim Grigsby, Jazmyne K.P. Davis, Margaret K. Tanner, Rick Doblin, Mykola Ostrovskyy
Publikováno v:
Physiology & Behavior. 199:343-350
Clinical trials have demonstrated that 3,4-methylenedioxymethamphetamine (MDMA) paired with psychotherapy is more effective at reducing symptoms of post-traumatic stress disorder (PTSD) than psychotherapy or pharmacotherapy, alone or in combination.
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. Action potential firing of serotonin dorsal raphe neurons is driven via α1-adrenergic receptors (α1-AR) activati
The delta glutamate receptors, GluD1R and GluD2R, are mysterious members of the ionotropic glutamate receptor family in that they are not gated by glutamate1,2. One theory is that they are scaffolding proteins or synaptic organizers strictly, rather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142c4ab07a143374e51b7c4fd60fc1a3
Extinction-based exposure therapy is the most common behavioral therapy for anxiety and trauma-related disorders, but fear tends to resurface even after successful extinction. Identification of novel strategies to enhance fear extinction and reduce f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efb17f2edda5cb6829b00625cb03c00
https://europepmc.org/articles/PMC6557445/
https://europepmc.org/articles/PMC6557445/
Autor:
Benjamin N. Greenwood, Mykola Ostrovskyy, Caroline E. Farmer, Nathan Gray, Esteban C. Loetz, Holly S. Hake, Adam J Rosberg, Courtney A. Bouchet, Megan A Miner
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 43(3)
Manipulations that increase dopamine (DA) signaling can enhance fear extinction, but the circuits involved remain unknown. DA neurons originating in the substantia nigra (SN) projecting to the dorsal striatum (DS) are traditionally viewed in the cont
Autor:
Esteban C. Loetz, Sondra T. Bland, Benjamin N. Greenwood, Brian A. Lloyd, Monika Fleshner, Caroline E. Farmer, Holly S. Hake, Takayuki Ishiwata
Publikováno v:
Behavioural brain research. 323
Exercise can enhance learning and memory and produce resistance against stress-related psychiatric disorders such as depression and anxiety. In rats, these beneficial effects of exercise occur regardless of exercise controllability: both voluntary an