Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Holly R Hack"'
1
Akademický článek
Analytical validation of quantitative SARS-CoV-2 subgenomic and viral load laboratory developed tests conducted on the Panther Fusion® (Hologic) with preliminary application to clinical samples.
Autor: Ines Lakhal-Naouar, Holly R Hack, Edgar Moradel, Amie Jarra, Hannah L Grove, Rani M Ismael, Steven Padilla, Dante Coleman, Jason Ouellette, Janice Darden, Casey Storme, Kristina K Peachman, Tara L Hall, Mark E Huhtanen, Paul T Scott, Shilpa Hakre, Linda L Jagodzinski, Sheila A Peel
Publikováno v: PLoS ONE, Vol 18, Iss 6, p e0287576 (2023)
ObjectiveValidate the performance characteristics of two analyte specific, laboratory developed tests (LDTs) for the quantification of SARS-CoV-2 subgenomic RNA (sgRNA) and viral load on the Hologic Panther Fusion® using the Open Access functionalit
Externí odkaz: https://doaj.org/article/f9ca43cf817f44cab7a4ef6f4b313754
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2
Akademický článek
Validation of SARS-CoV-2 pooled testing for surveillance using the Panther Fusion® system: Impact of pool size, automation, and assay chemistry.
Autor: Rudolph Park, Prabha Chandrasekaran, Heather Hernandez, Ines Lakhal-Naouar, Kristina K Peachman, Holly R Hack, Dante Coleman, Jason Ouellette, Janice M Darden, Oussama M'hamdi, Victor A Sugiharto, Hua-Wei Chen, Megan A Schilling, Mark P Simons, Natalie D Collins, Yuliya S Johnson, Linda L Jagodzinski, Sheila A Peel
Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0276729 (2022)
Combining diagnostic specimens into pools has been considered as a strategy to augment throughput, decrease turnaround time, and leverage resources. This study utilized a multi-parametric approach to assess optimum pool size, impact of automation, an
Externí odkaz: https://doaj.org/article/c7a2d05d428e450d9f6b43d4f601180b
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3
Akademický článek
Performance evaluation of a laboratory developed PCR test for quantitation of HIV-2 viral RNA.
Autor: Linda L Jagodzinski, Mark M Manak, Holly R Hack, Ying Liu, Sheila A Peel
Publikováno v: PLoS ONE, Vol 15, Iss 2, p e0229424 (2020)
Management of Human Immunodeficiency Virus Type 2 (HIV-2) infections present unique challenges due to low viral titers, slow disease progression, and poor response to standard antiviral therapies. The need for a nucleic acid assay to detect and quant
Externí odkaz: https://doaj.org/article/0b55bfc0558a41dea40b3892d0cb126f
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4
Akademický článek
Discrepant amplification results during the development of an assay leads to reclassification of two AIDS reagent repository HIV-2 isolates as HIV-1.
Autor: Linda L Jagodzinski, Ying Liu, Holly R Hack, Catherine Kibirige, Sheila A Peel, Mark M Manak
Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96554 (2014)
The development and verification of HIV-2 assays depends in part on the availability of well-characterized samples, including those from reagent repositories. During the development of an HIV-2 RNA quantification assay, two HIV-2 viral isolates (CDC
Externí odkaz: https://doaj.org/article/c4802583a774485da7101aa690186c0b
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6
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge
Autor: Sandrine Soman, Shelly J. Krebs, Diane L. Bolton, Gregory D. Gromowski, Ines Lakhal-Naouar, Swagata Kar, Michelle Zemil, Linda L. Jagodzinski, Amy R. Henry, Robert A. Seder, Lindsay Wieczorek, Hannah Grove, Dominic Paquin-Proulx, Adrienne Winn, Daniel C. Douek, Holly R. Hack, Caitlin Kuklis, Kamil Radzyminski, Rafael De La Barrera, Matthew Gagne, Caroline E. Peterson, James F. Wood, Heather Hernandez, Alexander R. A. Anderson, Xiankun Zeng, Stasya Zarling, Wei-Hung Chen, Mark G. Lewis, Rajeshwer S. Sankhala, Prakriti Mudvari, Andrew Pekosz, Victoria R. Polonis, Maciel Porto, Mangala Rao, Paul V. Thomas, Eli Boritz, M. Gordon Joyce, Sheila A. Peel, Elham Bayat Mokhtari, Kathryn McGuckin Wuertz, Nelson L. Michael, Sharon P. Daye, Akshaya Ganesh, Agnes Hajduczki, Gary R. Matyas, Jeffrey W. Froude, Vincent Dussupt, Erica K. Barkei, Kayvon Modjarrad, Jeffrey R. Currier, Sandhya Vasan, Janice Darden, Isabella Swafford, Elizabeth J. Martinez, Mehul S. Suthar, Ming Dong
Publikováno v: npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
NPJ Vaccines
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine (SpFN), adjuvanted with the Army Liposomal Formulation QS21 (ALFQ), conferre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d6879f30ffb08ad0fbf153e2d2ece2
https://doaj.org/article/3d4762c8ae9d4d3e8004ffeb07a8b88e
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7
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters
Autor: Kathryn McGuckin Wuertz, Matthew Gagne, Sharon P. Daye, Gary R. Matyas, Erica K. Barkei, Swagata Kar, Rafael De La Barrera, Caroline E. Peterson, Elyham Bayat Mokhtari, Michelle Zemil, Linda L. Jagodzinski, Elizabeth J. Martinez, Sandrine Soman, Mehul S. Suthar, Wei-Hung Chen, M. Gordon Joyce, Sheila A. Peel, Dominic Paquin-Proulx, Heather Hernandez, Rajeshwer S. Sankhala, Sandhya Vasan, Stasya Zarling, Caitlin Kuklis, Janice Darden, Andrew Pekosz, Diane L. Bolton, Ming Dong, Mark G. Lewis, Xiankun Zeng, Paul V. Thomas, Victoria R. Polonis, James F. Wood, Marciel Porto, Prakriti Mudvari, Ines Elakhal Naouar, Daniel C. Douek, Shelly J. Krebs, Holly R. Hack, Mangala Rao, Eli Boritz, Gregory D. Gromowski, Kamil Radzyminski, Robert A. Seder, Alexander R. A. Anderson, Akshaya Ganesh, Hannah Grove, Isabella Swafford, Amy R. Henry, Adrienne Winn, Agnes Hajduczki, Nelson L. Michael, Kayvon Modjarrad, Jeffrey W. Froude, Lindsey Wieczorek, Vincent Dussupt, Jeffrey R. Currier
Publikováno v: bioRxiv
article-version (status) pre
article-version (number) 1
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of vaccine protection. We evaluated whether a spike ferritin nanoparticle vaccine (SpFN), adjuvanted with the Army Liposomal Formulation QS21 (ALFQ), conferred protectio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f22541b3a4b216dde47acf2f8f3ef8
https://doi.org/10.1101/2021.06.16.448525
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8
Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques
Autor: Kayvon Modjarrad, Aslaa Ahmed, Wei-Hung Chen, Mihret F. Amare, Vincent Dussupt, Elizabeth J. Martinez, Kendra J. Alfson, Rajeshwer S. Sankhala, Misook Choe, Jarrett A. Headley, Hilary M. Staples, Caroline E. Peterson, Xiankun Zeng, Natalia de Val, Mark G. Lewis, Paul T. Scott, Caroline Subra, Ricardo Carrion, M. Gordon Joyce, Sheila A. Peel, Kerri G. Lal, Sebastian Molnar, Ming Dong, James Brett Case, Anthony L. Cook, Rita E. Chen, David D. Ho, Agnes Hajduczki, Mangala Rao, Isabella Swafford, Dominic Paquin-Proulx, Camila Macedo Cincotta, Yaoxing Huang, Kathryn McGuckin Wuertz, Nicos Karasavvas, Shelly J. Krebs, Sharon P. Daye, Clayton A. Smith, Gary R. Matyas, Manoj S. Nair, Jeffrey R. Currier, Hanne A. Elyard, Nelson L. Michael, Ines Lakhal-Naouar, Michael S. Diamond, Erica K. Barkei, Diane L. Bolton, Sandhya Vasan, Linda L. Jagodzinski, Victoria R. Polonis, Gregory D. Gromowski, Alexander R. A. Anderson, Holly R. Hack, Hannah A.D. King, Paul V. Thomas, Kristina K. Peachman, William C. Chang
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
bioRxiv
Significance The emergence of SARS-CoV-2 variants of concern (VOCs) that reduce the efficacy of current COVID-19 vaccines is a major threat to pandemic control. We evaluate a SARS-CoV-2 spike receptor-binding domain ferritin nanoparticle protein vacc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e04c0ddd418f55c7db5df557222ec1b
https://doi.org/10.1101/2021.04.09.439166
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10
Impact of Early Antiretroviral Therapy on Detection of Cell-Associated HIV-1 Nucleic Acid in Blood by the Roche Cobas TaqMan Test
Autor: Donn J Colby, Nittaya Phanuphak, Mark de Souza, Joanna Freeman, Jennifer A. Malia, Ying Liu, Linda L. Jagodzinski, Nitiya Chomchey, Jintanat Ananworanich, Holly R. Hack, Sheila A. Peel, Mark M. Manak, Eugene Kroon, Nelson L. Michael, Michelle Lally
Publikováno v: Journal of clinical microbiology, 57(5). American Society for Microbiology
The Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 test, v2.0 (the CAP/CTM assay), was used to quantify cell-associated HIV-1 (CAH) nucleic acid in peripheral blood mononuclear cells (PBMC) from well-characterized clinical specimens from HIV-1-infected ind
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579138083cf212b918c496e85aa03773
https://doi.org/10.1128/jcm.01922-18
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