Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Holly Prentice"'
Autor:
Taehong Kwon, Holly Prentice, Jonas De Oliveira, Nyasha Madziva, Majid Ebrahimi Warkiani, Jean-François P. Hamel, Jongyoon Han
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Continuous production of biologics, a growing trend in the biopharmaceutical industry, requires a reliable and efficient cell retention device that also maintains cell viability. Current filtration methods, such as tangential flow filtration
Externí odkaz:
https://doaj.org/article/f3245607a2aa4041aa73c8e026a442cd
Autor:
Jeffrey L. Browning, Robert Hoffman, Dajun Yang, Fabienne Mackay, Shelia M. Violette, Werner Meier, Holly Prentice, Thomas Crowell, Joseph Amatucci, Konrad Miatkowski, Amie Carmillo, Mitchell Reff, Stephen Fawell, Matt Jarpe, William Yang, Erika Silverio, Glenna Heaney, Linda Griffith, Jane Ding, Cindy Bottiglio, Rebecca Kelly, Kathleen Wortham, Kendall Szeliga, Xianghong Xu, Steve Perrin, Norman Allaire, Weike Zeng, Apinya Ngam-ek, Alex Lukashin, Ellen Garber, Véronique Bailly, Cheryl Wilson, Doreen LePage, Matvey Lukashev
Supplementary Tables 1-3, Figure 1 from Targeting the Lymphotoxin-β Receptor with Agonist Antibodies as a Potential Cancer Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949c15071769d873b18784a3e14ade10
https://doi.org/10.1158/0008-5472.22366529.v1
https://doi.org/10.1158/0008-5472.22366529.v1
Data from Targeting the Lymphotoxin-β Receptor with Agonist Antibodies as a Potential Cancer Therapy
Autor:
Jeffrey L. Browning, Robert Hoffman, Dajun Yang, Fabienne Mackay, Shelia M. Violette, Werner Meier, Holly Prentice, Thomas Crowell, Joseph Amatucci, Konrad Miatkowski, Amie Carmillo, Mitchell Reff, Stephen Fawell, Matt Jarpe, William Yang, Erika Silverio, Glenna Heaney, Linda Griffith, Jane Ding, Cindy Bottiglio, Rebecca Kelly, Kathleen Wortham, Kendall Szeliga, Xianghong Xu, Steve Perrin, Norman Allaire, Weike Zeng, Apinya Ngam-ek, Alex Lukashin, Ellen Garber, Véronique Bailly, Cheryl Wilson, Doreen LePage, Matvey Lukashev
The lymphotoxin-β receptor (LTβR) is a tumor necrosis factor receptor family member critical for the development and maintenance of various lymphoid microenvironments. Herein, we show that agonistic anti-LTβR monoclonal antibody (mAb) CBE11 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b7ca6b964258f446d078607d18b2c0
https://doi.org/10.1158/0008-5472.c.6495179
https://doi.org/10.1158/0008-5472.c.6495179
Autor:
Jongyoon Han, Jonas De Oliveira, Majid Ebrahimi Warkiani, Jean-François P. Hamel, Holly Prentice, Nyasha Madziva, Taehong Kwon
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Continuous production of biologics, a growing trend in the biopharmaceutical industry, requires a reliable and efficient cell retention device that also maintains cell viability. Current filtration methods, such as tangential flow filtration using ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f411ebb9562afc4d19deff230c37fc86
http://europepmc.org/articles/PMC5532224
http://europepmc.org/articles/PMC5532224
Publikováno v:
Biotechnology Progress. 30:100-107
Optimal bioreactor harvest time is typically determined based on maximizing product titer without compromising product quality. We suggest that ease of downstream purification should also be considered during harvest. In this view, we studied the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa63be497272b856fe8dedff5866eb8
https://doi.org/10.1002/btpr.1827
https://doi.org/10.1002/btpr.1827
Publikováno v:
Biotechnology Progress. 23:458-464
The amount of recombinant product obtained from mammalian cells grown in a bioreactor is in part limited by achievable cell densities and the ability of cells to remain viable over extended periods of time. In an attempt to generate cell lines capabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cd816c7d44535eb8fcc91fd5ae95b0
https://doi.org/10.1021/bp060296y
https://doi.org/10.1021/bp060296y
Autor:
Holly Prentice, Elena Vasilyeva, Frederick R. Taylor, Ellen Garber, R. Blake Pepinsky, Hans A. Fajardo
Publikováno v:
Analytical Biochemistry. 353:204-208
Human IgG4 subtype antibodies have often been reported to have a significant portion (5-50%) of a heavy chain-light chain dimer ("half-antibody") on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), in which the heavy chain is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beeab70529b6649e01e1ef6eaf7c7251
https://doi.org/10.1016/j.ab.2006.02.022
https://doi.org/10.1016/j.ab.2006.02.022
Autor:
St. John Skilton, Holly Prentice, Martha Stapels, Alex Xenopoulos, Catalin E. Doneanu, Weibin Chen, Keith Fadgen, Jim Murphy
Publikováno v:
mAbs. 4(1)
Assays for identification and quantification of host-cell proteins (HCPs) in biotherapeutic proteins over 5 orders of magnitude in concentration are presented. The HCP assays consist of two types: HCP identification using comprehensive online two-dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d7672f573140e7393290b633b84cbe
https://pubmed.ncbi.nlm.nih.gov/22327428
https://pubmed.ncbi.nlm.nih.gov/22327428
Autor:
Thomas Crowell, Xianghong Xu, Veronique Bailly, Konrad Miatkowski, Matvey E. Lukashev, Dajun Yang, Werner Meier, Holly Prentice, Stephen Fawell, Jeffrey L. Browning, Matthew Jarpe, Ellen Garber, Linda Griffith, Robert M. Hoffman, William Yang, Cindy Bottiglio, Joseph Amatucci, Amie N. Carmillo, Erika Lorraine Silverio, Alex Lukashin, Rebecca Kelly, Steve Perrin, Fabienne Mackay, Kathleen Wortham, Norman Allaire, Weike Zeng, Kendall Szeliga, Mitchell Reff, Glenna Heaney, Cheryl A. Wilson, Doreen Lepage, Jane Ding, Apinya Ngam-ek, Shelia M. Violette
Publikováno v:
Cancer research. 66(19)
The lymphotoxin-β receptor (LTβR) is a tumor necrosis factor receptor family member critical for the development and maintenance of various lymphoid microenvironments. Herein, we show that agonistic anti-LTβR monoclonal antibody (mAb) CBE11 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b463f7269d38dec18a9933c3416afb5e
https://pubmed.ncbi.nlm.nih.gov/17018619
https://pubmed.ncbi.nlm.nih.gov/17018619
Publikováno v:
Journal of biotechnology. 128(1)
An expression vector has been generated using a gene highly expressed under conditions found in a typical fed-batch bioreactor process. The ferritin heavy chain (HC) gene exhibits higher levels of expression in the late stages of a fed-batch bioreact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d088ccde8f5ddd2cf801ca9a7146d3a
https://pubmed.ncbi.nlm.nih.gov/17083990
https://pubmed.ncbi.nlm.nih.gov/17083990