Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Holly Pitman"'
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Abstract 2463: Enhancing the antileukemic activity of venetoclax against leukemia stem cells by targeting oxidative phosphorylation through dual inhibition of PI3K and HDAC
Autor: Lisa Polin, Hasini A. Kalpage, Holly Pitman, Jing Li, Jeffrey W. Taub, Yubin Ge, Maik Hüttemann, Katie Hege
Publikováno v: Cancer Research. 81:2463-2463
Over 40% of acute myeloid leukemia (AML) patients experience relapse after remission from intensive chemotherapy and stem cell transplant. Therefore, novel therapies are in demand to target the root cause of relapse, leukemia stem cells (LSCs). Recen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65ba33b8bd70d28844070f3624c52bdd
https://doi.org/10.1158/1538-7445.am2021-2463
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2
MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome
Autor: Lital Shaham, Maureen McNulty, Yaron Goren, John D. Crispino, Holly Pitman, Yubin Ge, Shulamit Michaeli, Stella T. Chou, Mitchell J. Weiss, Berthold Göttgens, Shai Izraeli, Marloes R. Tijssen, Ifat Geron, Yehudit Birger, Benjamin Sredni, Omer Schwartzman, Jeffrey W. Taub, Elena Vendramini, Liat Goldberg
Publikováno v: Blood. 125:1292-1301
Children with Down syndrome (DS) are at increased risk for acute myeloid leukemias (ML-DS) characterized by mixed megakaryocytic and erythroid phenotype and by acquired mutations in the GATA1 gene resulting in a short GATA1s isoform. The chromosome 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75363ea389fc00b1a989b4b1ab6af47
https://doi.org/10.1182/blood-2014-06-581892
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