Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Holly N. Haver"'
Autor:
Felicia N. Williams, Kanesha L. Travis, Holly N. Haver, Anna D. Umano, Yaneli Guerra-Hernandez, K. Matthew Scaglione
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Among sequenced organisms, the genome of Dictyostelium discoideum is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes. This results in the Dictyostelium proteome encoding for thousands of
Externí odkaz:
https://doaj.org/article/cb30df18d5364372af7a39de904dd4c0
Autor:
Holly N. Haver, K. Matthew Scaglione
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis. While many single-cellular model systems lac
Externí odkaz:
https://doaj.org/article/ba2b6f9241cd4cb580bff482b44c7806
Autor:
Holly N. Haver, Michael Wedemeyer, Erin Butcher, Francis C. Peterson, Brian F. Volkman, K. Matthew Scaglione
Publikováno v:
ACS Chemical Biology. 18:549-560
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a8827593aec0c7fb25939276a6285fc
https://doi.org/10.1021/acschembio.2c00893
https://doi.org/10.1021/acschembio.2c00893
UbcH5 Interacts with Substrates to Participate in Lysine Selection with the E3 Ubiquitin Ligase CHIP
Autor:
Holly N Haver, Theodore Keppel, Kenneth Matthew Scaglione, Adam J. Kanack, Rachel E. Klevit, Rebekah L. Gundry, Vinayak Vittal
Publikováno v:
Biochemistry
The E3 ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP) plays a critical role in regulating the ubiquitin-dependent degradation of misfolded proteins. CHIP mediates the ubiquitination of the α-amino-terminus of substrates with the E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc59739d29d693516975ff81072f9e77
https://doi.org/10.1021/acs.biochem.0c00084
https://doi.org/10.1021/acs.biochem.0c00084
Autor:
Stephanie Santarriaga, Alicia S. Fikejs, John M. Egner, Samantha L Sison, Brian A. Link, Adam J. Kanack, Holly N. Haver, K. Matthew Scaglione, R. Blake Hill, Allison D. Ebert, Jonathan R. Bostrom, Emily R Seminary
Publikováno v:
Molecular Cell. 71:216-228.e7
Summary The polyglutamine (polyQ) diseases are a group of nine neurodegenerative diseases caused by the expansion of a polyQ tract that results in protein aggregation. Unlike other model organisms, Dictyostelium discoideum is a proteostatic outlier,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca04590bbb860bb14dd645766a755ff
https://doi.org/10.1016/j.molcel.2018.07.008
https://doi.org/10.1016/j.molcel.2018.07.008