Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Holly Mole"'
Autor:
Chun Wai Wong, Christos Evangelou, Kieran N. Sefton, Rotem Leshem, Wei Zhang, Vishaka Gopalan, Sorayut Chattrakarn, Macarena Lucia Fernandez Carro, Erez Uzuner, Holly Mole, Daniel J. Wilcock, Michael P. Smith, Kleita Sergiou, Brian A. Telfer, Dervla T. Isaac, Chang Liu, Nicholas R. Perl, Kerrie Marie, Paul Lorigan, Kaye J. Williams, Patricia E. Rao, Raghavendar T. Nagaraju, Mario Niepel, Adam F. L. Hurlstone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Resistance mechanisms to immune checkpoint blockade therapy (ICBT) limit its response duration and magnitude. Paradoxically, Interferon γ (IFNγ), a key cytokine for cellular immunity, can promote ICBT resistance. Using syngeneic mouse tumo
Externí odkaz:
https://doaj.org/article/93f86ebcf5e046d68cb9b2272850303f
Autor:
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background Targeting of solid cancers with chimeric antigen receptor (CAR)-T cells is limited by the lack of suitable tumor-specific antigens and the immunosuppressive, desmoplastic tumor microenvironment that impedes CAR-T cell infiltration, activit
Externí odkaz:
https://doaj.org/article/050b5733a92d4347b81bd4fe65768fbc
Autor:
Karoliina Tuomela, Debayan Mukherjee, Ashley R. Ambrose, Ashish Harikrishnan, Holly Mole, Adam Hurlstone, Björn Önfelt, Jamie Honeychurch, Daniel M. Davis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Radiotherapy is one of the most common forms of cancer treatment used today. Its impact in directly killing cancer cells, and on antitumour immunity, is well recognized, but its effect on immune cell–cancer cell interactions is not ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1455829fd22de96230faa92a7b633efa
https://doi.org/10.1073/pnas.2111900119
https://doi.org/10.1073/pnas.2111900119
Autor:
Roberto Díez-Martínez, Irene Palacios, María C. Montoya, Patricia Letrado, Holly Mole, Jorge Barriuso, Julen Oyarzabal, Adam Hurlstone
Publikováno v:
Cancers
Volume 13
Issue 15
Letrado, P, Mole, H, Montoya, M, Palacios, I, Barriuso, J, Hurlstone, A, Díez-martínez, R & Oyarzabal, J 2021, ' Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study ', Cancers, vol. 13, no. 15, pp. 3705 . https://doi.org/10.3390/cancers13153705
Cancers, Vol 13, Iss 3705, p 3705 (2021)
Volume 13
Issue 15
Letrado, P, Mole, H, Montoya, M, Palacios, I, Barriuso, J, Hurlstone, A, Díez-martínez, R & Oyarzabal, J 2021, ' Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study ', Cancers, vol. 13, no. 15, pp. 3705 . https://doi.org/10.3390/cancers13153705
Cancers, Vol 13, Iss 3705, p 3705 (2021)
Zebrafish embryo tumor transplant models are widely utilized in cancer research. Compared with traditional murine models, the small size and transparency of zebrafish embryos combined with large clutch sizes that increase statistical power and cheap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2608ab6abb25d441ace591c974b517ea
https://pubmed.ncbi.nlm.nih.gov/34359605
https://pubmed.ncbi.nlm.nih.gov/34359605