Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Holly M. Wobma"'
Autor:
Brandon A. Guenthart, John D. O’Neill, Jinho Kim, Dawn Queen, Scott Chicotka, Kenmond Fung, Michael Simpson, Rachel Donocoff, Michael Salna, Charles C. Marboe, Katherine Cunningham, Susan P. Halligan, Holly M. Wobma, Ahmed E. Hozain, Alexander Romanov, Gordana Vunjak-Novakovic, Matthew Bacchetta
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross-circulation platform enables the regeneration of severely damaged lungs in a swine model of g
Externí odkaz:
https://doaj.org/article/d5b8dc81c66442c485f24ef1186a3a1f
Autor:
Holly M Wobma, Malika Kapadia, Haesook T. Kim, Francesca Alvarez-Calderon, Susanne Baumeister, Christine Duncan, Suzanne Forrest, Lev Gorfinkel, Jennifer Huang, Leslie Elaine Lehmann, Hojun Li, Marc Andre Schwartz, John Koreth, Jerome Ritz, Leslie S Kean, Jennifer S Whangbo
Publikováno v:
Blood Advances.
The majority of patients with chronic graft-vs-host disease are steroid refractory (SR-cGVHD), creating a need for safe and effective therapies. Subcutaneous low-dose interleukin-2 (LD IL-2), which preferentially expands CD4+ regulatory T cells (Treg
Autor:
Holly M. Wobma, Prakash Satwani, Larisa Broglie, Diane George, Susana Moscoso, Monica Bhatia, James Garvin, Zhezhen Jin
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:1318-1325
Allogeneic hematopoietic cell transplantation (HCT) has the capacity to cure numerous malignant and nonmalignant disorders. A dreaded complication is graft failure (GF), as it puts patients at high risk of infection and disease relapse. There are few
Autor:
Katherine M. Cunningham, Brandon A. Guenthart, Dawn Queen, Rachel Donocoff, Jinho Kim, John D. O’Neill, Matthew Bacchetta, Ahmed E. Hozain, Gordana Vunjak-Novakovic, Holly M. Wobma, Charles C. Marboe, Michael T. Simpson, Alexander Romanov, Michael Salna, Kenmond Fung, Scott Chicotka, Susan P. Halligan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
The number of available donor organs limits lung transplantation, the only lifesaving therapy for the increasing population of patients with end-stage lung disease. A prevalent etiology of injury that renders lungs unacceptable for transplantation is
Autor:
Holly M. Wobma, Prakash Satwani
Publikováno v:
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 60(1)
Mesenchymal stromal cells (MSC) are multipotent precursor cells that can be derived from a variety of tissue sources, with a working definition based on immunophenotyping and cell differentiation capacity. Despite historical roots in the field of tis
Autor:
Zhezhen Jin, Prakash Satwani, Monica Bhatia, Courtney Baker, Marc D Foca, James Garvin, Holly M. Wobma, Alicia K. Chang, Diane George
Publikováno v:
Pediatric transplantationREFERENCES. 25(4)
BACKGROUND HCT leaves patients in a relative state of immune deficiency both during their initial transplant admission and for several years following discharge. NTM are generally harmless colonizers of the outside environment, but for immunocompromi
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 7 (2019)
Frontiers in Pediatrics, Vol 7 (2019)
Chronic recurrent multifocal osteomyelitis (CRMO) is an uncommon cause of chronic inflammatory bone pain in children that can be disabling. Often, this diagnosis is considered only after a prolonged workup, leading to frustration for families and unn
Publikováno v:
Medical Education. 55:646-646
Autor:
Mariko Kanai, Hao Wei Li, Stephen P. Ma, Ying Shih, Raimon Duran-Struuck, Robert Winchester, Holly M. Wobma, Shahar Goeta, Gordana Vunjak-Novakovic, Lewis M. Brown
Publikováno v:
Journal of immunology and regenerative medicine. 1
The immunosuppressive capacity of human mesenchymal stromal cells (MSCs) renders them promising candidates for treating diverse immune disorders. However, after hundreds of clinical trials, there are still no MSC therapies approved in the United Stat
Autor:
Tylor Walsh, Antos Shakhbazau, Rajiv Midha, Leila Mirfeizi, Holly M. Wobma, Bhagat Singh, Michael S. Kallos, Ranjan Kumar
Publikováno v:
Biotechnology and Bioengineering. 113:393-402
Emerging bioreactor technologies offer an effective way for scaled-up production of large numbers of cells for cell therapy applications. One of the clinical paradigms where cell therapy can be an asset is restorative neurosciences. Nerve repair can