Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Holly M. Cline‐Fedewa"'
Autor:
Lauren G. Poole, Asmita Pant, Holly M. Cline‐Fedewa, Kurt J. Williams, Bryan L. Copple, Joseph S. Palumbo, James P. Luyendyk
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 906-917 (2020)
Abstract Background Blood coagulation protease activity is proposed to drive hepatic fibrosis through activation of protease‐activated receptors (PARs). Whole‐body PAR‐1 deficiency reduces experimental hepatic fibrosis, and in vitro studies sug
Externí odkaz:
https://doaj.org/article/bc24aceea5e740aebce30646df56704d
Autor:
Woosuk S. Hur, David S. Paul, Emma G. Bouck, Oscar A. Negrón, Jean-Marie Mwiza, Lauren G. Poole, Holly M. Cline-Fedewa, Emily G. Clark, Lih Jiin Juang, Jerry Leung, Christian J. Kastrup, Tatiana P. Ugarova, Alisa S. Wolberg, James P. Luyendyk, Wolfgang Bergmeier, Matthew J. Flick
Publikováno v:
Blood. 139:1374-1388
Genetic variants within the fibrinogen Aα chain encoding the αC-region commonly result in hypodysfibrinogenemia in patients. However, the (patho)physiological consequences and underlying mechanisms of such mutations remain undefined. Here, we gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bc72409136dacd6973d037830ae438
https://doi.org/10.1182/blood.2021012537
https://doi.org/10.1182/blood.2021012537