Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Holly M Brown"'
Autor:
Jiamei Han, Jiao Wang, Hongwei Shi, Qian Li, Shibo Zhang, Hao Wu, Wenjun Li, Linhua Gan, Holly M. Brown-Borg, Wei Feng, Yu Chen, Robert Chunhua Zhao
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100544- (2023)
Senescence is a cellular response characterized by cells irreversibly stopping dividing and entering a state of permanent growth arrest. One of the underlying pathophysiological causes of senescence is the oxidative stress-induced damage, indicating
Externí odkaz:
https://doaj.org/article/5f0231fb55004b48a8bd12ccc2cdac3e
Autor:
Grant R. Tomkinson, Tetsuhiro Kidokoro, Trevor J. Dufner, Shingo Noi, John S. Fitzgerald, Holly M. Brown-Borg
Publikováno v:
Journal of Sport and Health Science, Vol 10, Iss 4, Pp 462-469 (2021)
Background: The 6-minute walking distance (6MWD) is an excellent measure of both functional endurance and health. The primary aim of this study was to estimate temporal trends in 6MWD for older Japanese adults between 1998 and 2017; the secondary aim
Externí odkaz:
https://doaj.org/article/6886da78f0d746ff93d3c804394356cb
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Background Cytauxzoon felis is a tick-transmitted apicomplexan that causes cytauxzoonosis in domestic cats (Felis catus). Even with intensive care, the mortality rate of acute cytauxzoonosis approaches 40% in domestic cats, while bobcats (Ly
Externí odkaz:
https://doaj.org/article/c3ad398dd6c24d35a65df625b79d3ade
Autor:
Mitchell Thelen, Holly M. Brown-Borg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
The aging process causes many changes to the brain and is a major risk factor for the development of neurodegenerative diseases such as Alzheimer's Disease (AD). Despite an already vast amount of research on AD, a greater understanding of the disease
Externí odkaz:
https://doaj.org/article/6aa741caaa7a49318832df9b93e388e7
Autor:
Tina Wang, Brian Tsui, Jason F. Kreisberg, Neil A. Robertson, Andrew M. Gross, Michael Ku Yu, Hannah Carter, Holly M. Brown-Borg, Peter D. Adams, Trey Ideker
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising the question of whether it can also be slowed, for ex
Externí odkaz:
https://doaj.org/article/fe635a542c904dd5982d2d94c85510f1
Autor:
John J. Cole, Neil A. Robertson, Mohammed Iqbal Rather, John P. Thomson, Tony McBryan, Duncan Sproul, Tina Wang, Claire Brock, William Clark, Trey Ideker, Richard R. Meehan, Richard A. Miller, Holly M. Brown-Borg, Peter D. Adams
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-16 (2017)
Abstract Background Age-associated epigenetic changes are implicated in aging. Notably, age-associated DNA methylation changes comprise a so-called aging “clock”, a robust biomarker of aging. However, while genetic, dietary and drug interventions
Externí odkaz:
https://doaj.org/article/9e5c8d1b58dc4f46b45aaefafe9077fd
Autor:
Holly M Brown-Borg
Publikováno v:
J Gerontol A Biol Sci Med Sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1479a6ce99c2d8c6d81174b0144113d0
https://pubmed.ncbi.nlm.nih.gov/35436323
https://pubmed.ncbi.nlm.nih.gov/35436323
Autor:
Laís R. Perazza, Adam C. Gower, Holly M. Brown-Borg, Paola Divieti Pajevic, LaDora V. Thompson
Publikováno v:
GeroScience.
Frailty in aging is driven by the dysregulation of multiple biological pathways. Protectin DX (PDX) is a docosahexaenoic acid (DHA)-derived molecule that alleviates many chronic inflammatory disorders, but its potential effects on frailty remain unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acc55025fa502984d55fbf9e66d6126
https://doi.org/10.1007/s11357-023-00789-3
https://doi.org/10.1007/s11357-023-00789-3
Autor:
Brun Ulfhake, Shumin Zhou, Xiaoyue Wang, Huafei Li, Haoying Xu, Shihua Wang, Xingyan An, Gongxin Peng, Shuang Peng, Tingdong Yan, Robert Chunhua Zhao, Jingqi Liu, Zhen Xu, Guangliang Shan, Georgina M. Ellison-Hughes, Sihuan Xu, Zhi Zheng, Jing Li, Sasanka Chakrabarti, Lee Wei Lim, Eric Gilson, Fengchun Zhang, Huanxing Su, Qin Han, Yinghao Cao, Yan-Qing Ma, Antonio Cano, Jiao Wang, Jinming Gao, Ilia Stambler, Hongcui Cao, Alexey Moskalev, Calogero Caruso, Luchan Deng, Yan Liu, Xuebin Qu, Rongjia Zhu, Zhe Li, Dayong Xu, Zhonghui Zhang, Holly M. Brown-Borg, Kyung Jin Min, Wei Hou, Hongling Li, Kunlin Jin, Ronghua Jin, Jiaqi Zhu, Yingmei Feng, Tao Huang, Jianshe Yan, Yanlei Yang, Feng Wei
Publikováno v:
Cell Research. 31:1244-1262
The infusion of coronavirus disease 2019 (COVID-19) patients with mesenchymal stem cells (MSCs) potentially improves clinical symptoms, but the underlying mechanism remains unclear. We conducted a randomized, single-blind, placebo-controlled (29 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0489ace67c2e578a70190d2619c1643b
https://doi.org/10.1038/s41422-021-00573-y
https://doi.org/10.1038/s41422-021-00573-y
Autor:
Holly M. Brown-Borg, Tetsuhiro Kidokoro, Grant R. Tomkinson, John S. Fitzgerald, Trevor J. Dufner, Shingo Noi
Publikováno v:
Journal of Sport and Health Science, Vol 10, Iss 4, Pp 462-469 (2021)
Journal of Sport and Health Science
Journal of Sport and Health Science
Highlights • There has been a steady, moderate improvement in mean 6-minute walking distance (6MWD) for older Japanese adults (aged 65–79 years) between 1998 and 2017. • Gender- and age-related temporal differences in mean 6MWD were negligible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451cb717ca264368f9c2dbd72b67c8cb
http://www.sciencedirect.com/science/article/pii/S2095254620300739
http://www.sciencedirect.com/science/article/pii/S2095254620300739