Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Holly M, Funk"'
Publikováno v:
ACS Omega, Vol 9, Iss 23, Pp 25063-25072 (2024)
Externí odkaz:
https://doaj.org/article/dfc0384feade4fee8b77fa41b2f27afd
Autor:
Holly M Funk, Ruoxia Zhao, Maggie Thomas, Sarah M Spigelmyer, Nichlas J Sebree, Regan O Bales, Jamison B Burchett, Justen B Mamaril, Patrick A Limbach, Michael P Guy
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242737 (2020)
Posttranscriptional modification of tRNA is critical for efficient protein translation and proper cell growth, and defects in tRNA modifications are often associated with human disease. Although most of the enzymes required for eukaryotic tRNA modifi
Externí odkaz:
https://doaj.org/article/e7f239aef046469c8bc28f0291c60ace
Autor:
Holly M. Funk, Daisy J. DiVita, Hannah E. Sizemore, Kendal Wehrle, Catherine L. W. Miller, Morgan E. Fraley, Alex K. Mullins, Adrian R. Guy, Eric M. Phizicky, Michael P. Guy
Publikováno v:
ACS Omega. 7:13667-13675
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbd3f8821f09a0eb6bd75f7e18d5024a
https://doi.org/10.1021/acsomega.1c07231
https://doi.org/10.1021/acsomega.1c07231
Autor:
Holly M, Funk, Daisy J, DiVita, Hannah E, Sizemore, Kendal, Wehrle, Catherine L W, Miller, Morgan E, Fraley, Alex K, Mullins, Adrian R, Guy, Eric M, Phizicky, Michael P, Guy
Publikováno v:
ACS omega. 7(16)
Posttranscriptional tRNA modifications are essential for proper gene expression, and defects in the enzymes that perform tRNA modifications are associated with numerous human disorders. Throughout eukaryotes, 2'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::966e55bf83b7241528a0c00b660e4022
https://pubmed.ncbi.nlm.nih.gov/35559166
https://pubmed.ncbi.nlm.nih.gov/35559166
Autor:
Shaheena Khan, Jonathan A. Hickson, Tamara L. Lotan, Sophie Thiolloy, Holly M. Funk, Carrie W. Rinker-Schaeffer, Angela F. Drew, Gail S. Prins
Publikováno v:
Clinical & Experimental Metastasis. 27:185-196
Despite the potentially crucial contributions of the omentum in the regulation of ovarian cancer metastatic growth, it remains a poorly understood organ. Due to its anatomic location and structural fragility, the omentum presents inherent challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5638fd4f0b0270cd4b96e31f8679a0
https://doi.org/10.1007/s10585-010-9317-0
https://doi.org/10.1007/s10585-010-9317-0
Autor:
Molly M. McFarland-Mancini, Taofic Mounajjed, Mingfu Zhou, Nader Husseinzadeh, Holly M. Funk, Angela F. Drew
Publikováno v:
Cancer Immunology, Immunotherapy. 58:1375-1385
Recent studies have implicated inflammation in the initiation and progression of ovarian cancer, though the mechanisms underlying this effect are still not clear. Toll-like receptors (TLRs) allow immune cells to recognize pathogens and to trigger inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a2bec158416bb69a38e971eaef5e47
https://doi.org/10.1007/s00262-008-0650-y
https://doi.org/10.1007/s00262-008-0650-y
Autor:
David R. Plas, Holly M. Funk, Carol A. Mercer, Aleksey Porollo, Premkumar Vummidi Giridhar, Catherine A. Gallo, Angela F. Drew
Publikováno v:
Clinicalexperimental metastasis. 28(8)
One of the earliest metastatic events in human ovarian cancer, tumor spread to the omentum, may be influenced by expression of interleukin 6 (IL6) and its cognate receptor (IL6Rα). Previous reports have shown that IL6 and IL6Rα expression is elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d86f83e1978061e26c938356039ede6
https://pubmed.ncbi.nlm.nih.gov/21887537
https://pubmed.ncbi.nlm.nih.gov/21887537
Publikováno v:
Journal of Biological Chemistry, 286, 10834-46
Journal of Biological Chemistry, 286, 12, pp. 10834-46
Journal of Biological Chemistry, 286, 12, pp. 10834-46
Contains fulltext : 97454.pdf (Publisher’s version ) (Open Access) To generate and maintain epithelial cell polarity, specific sorting of proteins into vesicles destined for the apical and basolateral domain is required. Syntaxin 3 and 4 are apical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab393e28e114292e30a6a401456306c
http://hdl.handle.net/2066/97454
http://hdl.handle.net/2066/97454
Autor:
Andrew M. Paluch, Carol A. Mercer, Premkumar Vummidi Giridhar, Angela F. Drew, Mingfu Zhou, Sara C. Kozma, Holly M. Funk, Molly M. McFarland-Mancini
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(12)
IL-6 modulates immune responses and is essential for timely wound healing. As the functions mediated by IL-6 require binding to its specific receptor, IL-6Rα, it was expected that mice lacking IL-6Rα would have the same phenotype as IL-6–deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5919134eeb2ac52ab6ff269bdea4f480
https://pubmed.ncbi.nlm.nih.gov/20483735
https://pubmed.ncbi.nlm.nih.gov/20483735
Publikováno v:
American Journal of Obstetrics and Gynecology. 203:230.e1-230.e8
Objective The objective of the study was to investigate interleukin-6 receptor (IL6R) isoforms and sheddases in the ovarian tumor microenvironment. Study Design Expression of IL6R and sheddases was measured in tissue samples of papillary serous ovari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d2625b6fc9b57831195f3431aa6106
https://doi.org/10.1016/j.ajog.2010.03.034
https://doi.org/10.1016/j.ajog.2010.03.034