Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Holly L, Chapman"'
Autor:
Holly L. Chapman, Noelle C. Anastasio
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 134-134 (2024)
OBJECTIVES/GOALS: Neuropsychiatric disorders classified as synaptopathies are marked by a glutamate-associated hypofrontality which impacts decision making and impulsivity. We hypothesized that behavioral efficacy of the psychoplastogen ketamine is m
Externí odkaz:
https://doaj.org/article/a0b0c8415c0040b0a6a37b28620c8c13
Autor:
David H. Malin, Ping-Hsun Tsai, Joseph R. Campbell, Georgina L. Moreno, Holly L. Chapman, Aoi Suzaki, Mehrshad S. Keivan, Kaitlyn M. Gibbons, Erica R. Morales, Ethan S. Burstein, Christopher P. Ward
Publikováno v:
European Journal of Pharmacology. 939:175437
Pimavanserin is a highly selective 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3226e2dcc1766ec1ddc8d061aedb9b
https://doi.org/10.1016/j.ejphar.2022.175437
https://doi.org/10.1016/j.ejphar.2022.175437
Autor:
Veronica M. Campbell, Susan Stafford, Michelle A. Land, Noelle C. Anastasio, Holly L. Chapman, Brionna D. Davis-Reyes
Publikováno v:
Biochem Pharmacol
Impulsivity is a multifaceted behavioral manifestation with implications in several neuropsychiatric disorders. Glutamate neurotransmission through the N-methyl-D-aspartate receptors (NMDARs) in the medial prefrontal cortex (mPFC), an important brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1301aa14b83895a1c5dd754c56221ada
https://doi.org/10.1016/j.bcp.2019.07.007
https://doi.org/10.1016/j.bcp.2019.07.007
Autor:
Sonja J. Stutz, F. Gerard Moeller, Veronica Campbell, Ashley M. Smith, Kathryn A. Cunningham, Noelle C. Anastasio, Robert O. Fox, Holly L. Chapman
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43eda4df152533ca9b230b654ac442d8
https://doi.org/10.1096/fasebj.2021.35.s1.03889
https://doi.org/10.1096/fasebj.2021.35.s1.03889
Autor:
Sonja J. Stutz, Kathryn A. Cunningham, Frederick G. Moeller, Robert O. Fox, Holly L. Chapman, Erik J. Garcia, Noelle C. Anastasio, James M. Kasper
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac34de184cac42da53d1238bf3a643e5
https://doi.org/10.1096/fasebj.2021.35.s1.03708
https://doi.org/10.1096/fasebj.2021.35.s1.03708
Autor:
Noelle C. Anastasio, John A. Allen, Holly L. Chapman, Kathryn A. Cunningham, Lisa A. Elferink, Daniel E. Felsing, Brionna D. Davis-Reyes, F. Gerard Moeller, Michelle A. Land
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
A non-synonymous single nucleotide polymorphism of the human serotonin 5-HT2C receptor (5-HT2CR) gene that converts a cysteine to a serine at amino acid codon 23 (Cys23Ser) appears to impact 5-HT2CR pharmacology at a cellular and systems level. We hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4619a7ab8fa160acbdec2e4d41e7b9e
https://doi.org/10.1038/s41598-019-53124-2
https://doi.org/10.1038/s41598-019-53124-2
Autor:
Theodore M. Kamenecka, Angelo Blasio, Simone M. Giovanetti, Michael D. Cameron, Robert O. Messing, Matthew B. Pomrenze, Jingyi Wang, Christelle Doebelin, Jon Lindstrom, Holly L. Chapman, Victor Liaw, Alexander Kuryatov, Li Lin
Publikováno v:
Neuropsychopharmacology
There is increasing interest in developing drugs that act at α4β2 nicotinic acetylcholine receptors (nAChRs) to treat alcohol use disorder. The smoking cessation agent varenicline, a partial agonist of α4β2 nAChRs, reduces alcohol intake, but its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea2407be6ea72e8212bc31f113908ff
https://europepmc.org/articles/PMC6901472/
https://europepmc.org/articles/PMC6901472/
Autor:
Michelle A, Land, Holly L, Chapman, Brionna D, Davis-Reyes, Daniel E, Felsing, John A, Allen, F Gerard, Moeller, Lisa A, Elferink, Kathryn A, Cunningham, Noelle C, Anastasio
Publikováno v:
Scientific Reports
A non-synonymous single nucleotide polymorphism of the human serotonin 5-HT2C receptor (5-HT2CR) gene that converts a cysteine to a serine at amino acid codon 23 (Cys23Ser) appears to impact 5-HT2CR pharmacology at a cellular and systems level. We hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f414eba2ac587f88f7230069cdc7c115
https://pubmed.ncbi.nlm.nih.gov/31723224
https://pubmed.ncbi.nlm.nih.gov/31723224
Autor:
Rajani Maiya, Benjamin R. Kanter, Robert O. Messing, Thomas A. McMahon, Dev Gandhi, Dan Wang, Jacklyn Miller, Holly L. Chapman
Publikováno v:
Neuropharmacology
Reducing expression or inhibiting translocation of protein kinase C epsilon (PKCε) prolongs ethanol intoxication and decreases ethanol consumption in mice. However, we do not know if this phenotype is due to reduced PKCε kinase activity or to impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e8b2260201da423b4ada2740ee620d
http://hdl.handle.net/11250/2469694
http://hdl.handle.net/11250/2469694
Recombinant Interleukin-11 (rhIL-11) in Women with Refractory Menorrhagia and Von Willebrand Disease
Autor:
Rachel C. Jankowitz, Elizabeth P. Merricks, Timothy C. Nichols, Mark T. Kloos, Helen W. G. Franck, Margaret V. Ragni, Holly L. Chapman, Aaron Dillow
Publikováno v:
Blood. 112:1210-1210
Von Willebrand disease (VWD) is the single most common congenital bleeding disorder, and among women, menorrhagia is the most common bleeding symptom. Although DDAVP is the treatment of choice for those with type 1 VWD, its use may be limited by tach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2ab9213dea8266b1272db796e2de4b
https://doi.org/10.1182/blood.v112.11.1210.1210
https://doi.org/10.1182/blood.v112.11.1210.1210