Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Holly K. Koblish"'
Autor:
Lucia Mazzacurati, Robert J. Collins, Garima Pandey, Que T. Lambert-Showers, Narmin E. Amin, Ling Zhang, Matthew C. Stubbs, Pearlie K. Epling-Burnette, Holly K. Koblish, Gary W. Reuther
Publikováno v:
Blood Advances, Vol 3, Iss 22, Pp 3503-3514 (2019)
Abstract: Aberrant JAK2 tyrosine kinase signaling drives the development of Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis. However, JAK2 kinas
Externí odkaz:
https://doaj.org/article/587c347d89224f06a5f079374062a7ed
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Preclinical evaluation of drugs targeting the human immune system has posed challenges for oncology researchers. Since the commercial introduction of humanized mice, antitumor efficacy and pharmacodynamic studies can now be performed with
Externí odkaz:
https://doaj.org/article/78302d2af41441a18d73298cceec3f36
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Figure from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170fab3f863c9be0aad6f9e19f25879b
https://doi.org/10.1158/2159-8290.22540984.v1
https://doi.org/10.1158/2159-8290.22540984.v1
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Blocking the activity of the programmed cell death protein 1 (PD-1) inhibitory receptor with therapeutic antibodies against either the ligand (PD-L1) or PD-1 itself has proven to be an effective treatment modality for multiple cancers. Contrasting wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6486db56a65286928bd5907136280e12
https://doi.org/10.1158/2159-8290.c.6549529
https://doi.org/10.1158/2159-8290.c.6549529
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Table from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bbcf100cd3199695d65a7a2d3df77e
https://doi.org/10.1158/2159-8290.22540981.v1
https://doi.org/10.1158/2159-8290.22540981.v1
Autor:
Gregory Hollis, Wenqing Yao, Reid Huber, Peggy Scherle, Jeff Jackson, Swamy Yeleswaram, Cindy Marando, Ryan Geschwindt, Pramod Thekkat, Yue Zhang, Christina Stevens, Luping Lin, Darlise DiMatteo, Mark Rupar, Gengjie Yang, Chrysi Kanellopoulou, Stephen Rubin, Kevin O'Hayer, Maxim Soloviev, Sharon Diamond, Jingwei Li, Yan-ou Yang, Maryanne Covington, Elham Behshad, Kanishk Kapilashrami, Nina Zolotarjova, Alla Volgina, Hao Liu, Susan Spitz, Jonathan Rios-Doria, Richard Wynn, Phillip C.C. Liu, Liang-Chuan S. Wang, Liangxing Wu, Holly K. Koblish
Supplementary Data from Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739e2f7911a281a155113d1f5d765bd
https://doi.org/10.1158/2159-8290.22540987
https://doi.org/10.1158/2159-8290.22540987
Autor:
Grant A. Challen, Stephen T. Oh, Holly K. Koblish, Matthew C. Stubbs, Terrence N. Wong, Jared S. Fowles, Daniel A.C. Fisher, Tiandao Li, Maggie Allen, Ostap Kukhar, Hassan Bjeije, Won Kyun Koh, Nancy Issa, Wentao Han, Christine R. Zhang, Ethan Krug, Hamza Celik
Myeloproliferative neoplasms (MPN) are chronic blood diseases with significant morbidity and mortality. Although sequencing studies have elucidated the genetic mutations that drive these diseases, MPNs remain largely incurable with a significant prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a567f6f5f98a0e2722cba1117219dcd
https://doi.org/10.1158/2159-8290.c.6549361.v1
https://doi.org/10.1158/2159-8290.c.6549361.v1
Autor:
Grant A. Challen, Stephen T. Oh, Holly K. Koblish, Matthew C. Stubbs, Terrence N. Wong, Jared S. Fowles, Daniel A.C. Fisher, Tiandao Li, Maggie Allen, Ostap Kukhar, Hassan Bjeije, Won Kyun Koh, Nancy Issa, Wentao Han, Christine R. Zhang, Ethan Krug, Hamza Celik
Supplementary Figures 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86778ff5c2d7a876a216678ab35f0a37
https://doi.org/10.1158/2159-8290.22540360
https://doi.org/10.1158/2159-8290.22540360
Autor:
Grant A. Challen, Stephen T. Oh, Holly K. Koblish, Matthew C. Stubbs, Terrence N. Wong, Jared S. Fowles, Daniel A.C. Fisher, Tiandao Li, Maggie Allen, Ostap Kukhar, Hassan Bjeije, Won Kyun Koh, Nancy Issa, Wentao Han, Christine R. Zhang, Ethan Krug, Hamza Celik
Hematological comparison of MF patients versus PDXs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ff66c0f13b2518d81ffaaab1ec8881
https://doi.org/10.1158/2159-8290.22540357
https://doi.org/10.1158/2159-8290.22540357
Autor:
Grant A. Challen, Stephen T. Oh, Holly K. Koblish, Matthew C. Stubbs, Terrence N. Wong, Jared S. Fowles, Daniel A.C. Fisher, Tiandao Li, Maggie Allen, Ostap Kukhar, Hassan Bjeije, Won Kyun Koh, Nancy Issa, Wentao Han, Christine R. Zhang, Ethan Krug, Hamza Celik
Exome sequencing results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fee595b4886906d48090b82109c6e2
https://doi.org/10.1158/2159-8290.22540354
https://doi.org/10.1158/2159-8290.22540354