International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Autor: Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R. I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Joel Gelernter, Daniel F. Levey, Mark W. Logue, Renato Polimanti, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B. Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas- de- Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M. J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A. M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Scott R. Sponheim, Dan J. Stein, Jennifer S. Stevens, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda Van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Ross McD. Young, Keith A. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

Post-traumatic stress disorder (PTSD) is a common mental health problem. Here, the authors report a GWAS from the Psychiatric Genomics Consortium in which they identify two risk loci in European ancestry and one locus in African ancestry individuals

Externí odkaz: https://doaj.org/article/d39ff05b76b746a5b312681b5db7b9fc

Assessing the mediating role of emotion regulation and experiential avoidance within a posttraumatic stress disorder and racial trauma framework

Autor: Travis A. Cole, Chynna M. Dubuclet, Jennifer Valentine, Emilie A. Meyer, Holly K. Orcutt

Publikováno v: Psychological Trauma: Theory, Research, Practice, and Policy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcea1e9602281757389576345b5d4257
https://doi.org/10.1037/tra0001487

Obsessive-compulsive symptoms in sexual minorities

Autor: Caitlin M. Pinciotti, Holly K. Orcutt

Publikováno v: Psychology of Sexual Orientation and Gender Diversity. 8:487-495

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f27486bc3124064430d67b0e9747fa7f
https://doi.org/10.1037/sgd0000437

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

Autor: Alma Dzubur Kulenovic, Michael J. Lyons, Elizabeth A. Bolger, Kenneth J. Ruggiero, Zhewu Wang, Laramie E. Duncan, Bozo Lugonja, Joanne Voisey, José Miguel Caldas-de-Almeida, Regina E. McGlinchey, Laura J. Bierut, Michael A. Hauser, Jean C. Beckham, Dan J. Stein, Alexander C. McFarlane, Elbert Geuze, Victoria B. Risbrough, Douglas Maurer, Christy A. Denckla, Seth G. Disner, William P. Milberg, Erika J. Wolf, Scott R. Sponheim, Caroline M. Nievergelt, Henry R. Kranzler, Clement C. Zai, Antonia V. Seligowski, Miro Jakovljević, Katharina Domschke, Paul A. Arbisi, Thomas Werge, Vasiliki Michopoulos, Joel Gelernter, Sarah D. Linnstaedt, Nastassja Koen, Sonya B. Norman, Nicholas G. Martin, Janine D. Flory, Meghan M Brashear, Melissa A. Polusny, Nathan A. Kimbrel, Douglas L. Delahanty, Milissa L. Kaufman, Peter Roy-Byrne, Magali Haas, Monica Uddin, Matig R. Mavissakalian, William S. Kremen, Ole A. Andreassen, Marco P. Boks, Matthew S. Panizzon, Christiaan H. Vinkers, Bart P. F. Rutten, Heather Lasseter, Richard A. Shaffer, Aferdita Goci, Jessica L. Maples-Keller, Israel Liberzon, Melanie E. Garrett, Alicia K. Smith, Catrin Lewis, Dewleen G. Baker, Murray B. Stein, Xuejun Qin, Nikolaos P. Daskalakis, Sherry Winternitz, Douglas E. Williamson, Alex O. Rothbaum, David Forbes, Leigh van den Heuvel, Scott D. Gordon, Edward J. Trapido, Marti Jett, Ole Mors, Adam X. Maihofer, Christina M. Sheerin, Lori A. Zoellner, A.C. Bustamante, David M. Hougaard, Alexandra Evans, Chia-Yen Chen, Robert H. Pietrzak, Rachel Yehuda, Allison C. Provost, Matthew Peverill, Aarti Gautam, Bruce R. Lawford, Derrick Silove, Bekh Bradley, Gerome Breen, Charles F. Gillespie, Allison E. Ashley-Koch, Kerry J. Ressler, Christiane Wolf, Renato Polimanti, Jonathan Ian Bisson, Adriana Lori, Lynn M. Almli, Norah C. Feeny, Jonas Bybjerg-Grauholm, Guia Guffanti, Søren Bo Andersen, Anders D. Børglum, Elizabeth Ketema, Andrea L. Roberts, Marie Bμkvad-Hansen, Ross McD. Young, Jürgen Deckert, Jonathan Sebat, Rajendra A. Morey, P. B. Mortensen, Lindsay A. Farrer, Yunpeng Wang, Karestan C. Koenen, Joseph R. Calabrese, Bizu Gelaye, Jurjen J. Luykx, Andrew Ratanatharathorn, Charles P. Morris, S. Bryn Austin, Miranda Van Hooff, Edward S. Peters, Katie A. McLaughlin, Anthony P. King, Jonathan R. I. Coleman, Holly K. Orcutt, Keith A. Young, Samuel A. McLean, Jennifer S. Stevens, Rasha Hammamieh, Robert J. Ursano, Mark W. Miller, Allison E. Aiello, Charles R. Marmar, Esmina Avdibegović, Katy Torres, Elliot C. Nelson, Rany M. Salem, Martin H. Teicher, Rebecca Mellor, Karen-Inge Karstoft, Aliza P. Wingo, Alaptagin Khan, Michelle A. Williams, Dick Schijven, Merete Nordentoft, Ananda B. Amstadter, Shareefa Dalvie, Michelle F. Dennis, Mark J. Daly, Mark W. Logue, Soraya Seedat, Julia S. Seng, Carol E. Franz, Stephan Ripke, Karmel W. Choi, Sandro Galea, Richard A. Bryant, Ian Jones, Anders M. Dale, Wesley K. Thompson, Lauren A.M. Lebois, Sixto E. Sanchez, Ronald C. Kessler, Tanja Jovanovic, Divya Mehta, Jordan W. Smoller, Eric O. Johnson, John P. Rice, Andrew C. Heath, Nancy L. Saccone, Barbara O. Rothbaum, Alan L. Peterson, Meaghan O'Donnell, Sian M. J. Hemmings, Eric Vermetten, Dragan Babić, Hongyu Zhao, Tianying Wu, Christopher R. Erbes, Ariane Rung

Publikováno v: Biological Psychiatry, 91(7), 626-636. Elsevier Science
Maihofer, A X, Choi, K W, Coleman, J R I, Daskalakis, N P, Denckla, C A, Ketema, E, Morey, R A, Polimanti, R, Ratanatharathorn, A, Torres, K, Wingo, A P, Zai, C C, Aiello, A E, Almli, L M, Amstadter, A B, Andersen, S B, Andreassen, O A, Arbisi, P A, Ashley-Koch, A E, Austin, S B, Avdibegović, E, Borglum, A D, Babić, D, Bækvad-Hansen, M, Baker, D G, Beckham, J C, Bierut, L J, Bisson, J I, Boks, M P, Bolger, E A, Bradley, B, Brashear, M, Breen, G, Bryant, R A, Bustamante, A C, Bybjerg-Grauholm, J, Calabrese, J R, Caldas-de-Almeida, J M, Chen, C-Y, Dale, A M, Dalvie, S, Deckert, J R, Delahanty, D L, Dennis, M F, Disner, S G, Domschke, K, Duncan, L E, Džubur Kulenović, A, Erbes, C R, Evans, A, Farrer, L A, Feeny, N C, Flory, J D, Forbes, D, Franz, C E, Galea, S, Garrett, M E, Gautam, A, Gelaye, B, Gelernter, J, Geuze, E, Gillespie, C F, Goçi, A, Gordon, S D, Guffanti, G, Hammamieh, R, Hauser, M A, Heath, A C, Hemmings, S M J, Hougaard, D M, Jakovljević, M, Jett, M, Johnson, E O, Jones, I, Jovanovic, T, Qin, X-J, Karstoft, K-I, Kaufman, M L, Kessler, R C, Khan, A, Kimbrel, N A, King, A P, Koen, N, Kranzler, H R, Kremen, W S, Lawford, B R, Lebois, L A M, Lewis, C, Liberzon, I, Linnstaedt, S D, Logue, M W, Lori, A, Lugonja, B, Luykx, J J, Lyons, M J, Maples-Keller, J L, Marmar, C, Martin, N G, Maurer, D, Mavissakalian, M R, McFarlane, A, McGlinchey, R E, McLaughlin, K A, McLean, S A, Mehta, D, Mellor, R, Michopoulos, V, Milberg, W, Miller, M W, Morris, C P, Mors, O, Mortensen, P B, Nelson, E C, Nordentoft, M, Norman, S B, O'Donnell, M, Orcutt, H K, Panizzon, M S, Peters, E S, Peterson, A L, Peverill, M, Pietrzak, R H, Polusny, M A, Rice, J P, Risbrough, V B, Roberts, A L, Rothbaum, A O, Rothbaum, B O, Roy-Byrne, P, Ruggiero, K J, Rung, A, Rutten, B P F, Saccone, N L, Sanchez, S E, Schijven, D, Seedat, S, Seligowski, A V, Seng, J S, Sheerin, C M, Silove, D, Smith, A K, Smoller, J W, Sponheim, S R, Stein, D J, Stevens, J S, Teicher, M H, Thompson, W K, Trapido, E, Uddin, M, Ursano, R J, van den Heuvel, L L, van Hooff, M, Vermetten, E, Vinkers, C, Voisey, J, Wang, Y, Wang, Z, Werge, T, Williams, M A, Williamson, D E, Winternitz, S, Wolf, C, Wolf, E J, Yehuda, R, Young, K A, Young, R M, Zhao, H, Zoellner, L A, Haas, M, Lasseter, H, Provost, A C, Salem, R M, Sebat, J, Shaffer, R A, Wu, T, Ripke, S, Daly, M J, Ressler, K J, Koenen, K C, Stein, M B & Nievergelt, C M 2021, ' Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2021.09.020
Maihofer, A X, Choi, K W, Coleman, J R I, Daskalakis, N P, Denckla, C A, Ketema, E, Morey, R A, Polimanti, R, Ratanatharathorn, A, Torres, K, Wingo, A P, Zai, C C, Aiello, A E, Almli, L M, Amstadter, A B, Andersen, S B, Andreassen, O A, Arbisi, P A, Ashley-Koch, A E, Austin, S B, Avdibegović, E, Borglum, A D, Babić, D, Bækvad-Hansen, M, Baker, D G, Beckham, J C, Bierut, L J, Bisson, J I, Boks, M P, Bolger, E A, Bradley, B, Brashear, M, Breen, G, Bryant, R A, Bustamante, A C, Bybjerg-Grauholm, J, Calabrese, J R, Caldas-de-Almeida, J M, Chen, C Y, Dale, A M, Dalvie, S, Deckert, J, Delahanty, D L, Dennis, M F, Disner, S G, Domschke, K, Duncan, L E, Džubur Kulenović, A, Erbes, C R, Evans, A, Farrer, L A, Feeny, N C, Flory, J D, Forbes, D, Franz, C E, Galea, S, Garrett, M E, Gautam, A, Gelaye, B, Gelernter, J, Geuze, E, Gillespie, C F, Goçi, A, Gordon, S D, Guffanti, G, Hammamieh, R, Hauser, M A, Heath, A C, Hemmings, S M J, Hougaard, D M, Jakovljević, M, Jett, M, Johnson, E O, Jones, I, Jovanovic, T, Qin, X J, Karstoft, K I, Kaufman, M L, Kessler, R C, Khan, A, Kimbrel, N A, King, A P, Koen, N, Kranzler, H R, Kremen, W S, Lawford, B R, Lebois, L A M, Lewis, C, Liberzon, I, Linnstaedt, S D, Logue, M W, Lori, A, Lugonja, B, Luykx, J J, Lyons, M J, Maples-Keller, J L, Marmar, C, Martin, N G, Maurer, D, Mavissakalian, M R, McFarlane, A, McGlinchey, R E, McLaughlin, K A, McLean, S A, Mehta, D, Mellor, R, Michopoulos, V, Milberg, W, Miller, M W, Morris, C P, Mors, O, Mortensen, P B, Nelson, E C, Nordentoft, M, Norman, S B, O'Donnell, M, Orcutt, H K, Panizzon, M S, Peters, E S, Peterson, A L, Peverill, M, Pietrzak, R H, Polusny, M A, Rice, J P, Risbrough, V B, Roberts, A L, Rothbaum, A O, Rothbaum, B O, Roy-Byrne, P, Ruggiero, K J, Rung, A, Rutten, B P F, Saccone, N L, Sanchez, S E, Schijven, D, Seedat, S, Seligowski, A V, Seng, J S, Sheerin, C M, Silove, D, Smith, A K, Smoller, J W, Sponheim, S R, Stein, D J, Stevens, J S, Teicher, M H, Thompson, W K, Trapido, E, Uddin, M, Ursano, R J, van den Heuvel, L L, Van Hooff, M, Vermetten, E, Vinkers, C H, Voisey, J, Wang, Y, Wang, Z, Werge, T, Williams, M A, Williamson, D E, Winternitz, S, Wolf, C, Wolf, E J, Yehuda, R, Young, K A, Young, R M D, Zhao, H, Zoellner, L A, Haas, M, Lasseter, H, Provost, A C, Salem, R M, Sebat, J, Shaffer, R A, Wu, T, Ripke, S, Daly, M J, Ressler, K J, Koenen, K C, Stein, M B & Nievergelt, C M 2022, ' Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information ', Biological Psychiatry, vol. 91, no. 7, pp. 626-636 . https://doi.org/10.1016/j.biopsych.2021.09.020
Maihofer, A X, Choi, K W, Coleman, J R I, Daskalakis, N P, Denckla, C A, Ketema, E, Morey, R A, Polimanti, R, Ratanatharathorn, A, Torres, K, Wingo, A P, Zai, C C, Aiello, A E, Almli, L M, Amstadter, A B, Andersen, S B, Andreassen, O A, Arbisi, P A, Ashley-Koch, A E, Austin, S B, Avdibegović, E, Borglum, A D, Babić, D, Bækvad-Hansen, M, Baker, D G, Beckham, J C, Bierut, L J, Bisson, J I, Boks, M P, Bolger, E A, Bradley, B, Brashear, M, Breen, G, Bryant, R A, Bustamante, A C, Bybjerg-Grauholm, J, Calabrese, J R, Caldas-de-Almeida, J M, Chen, C-Y, Dale, A M, Dalvie, S, Deckert, J, Delahanty, D L, Dennis, M F, Disner, S G, Domschke, K, Duncan, L E, Džubur Kulenović, A, Erbes, C R, Evans, A, Farrer, L A, Feeny, N C, Flory, J D, Forbes, D, Franz, C E, Galea, S, Garrett, M E, Gautam, A, Gelaye, B, Gelernter, J, Geuze, E, Gillespie, C F, Goçi, A, Gordon, S D, Guffanti, G, Hammamieh, R, Hauser, M A, Heath, A C, Hemmings, S M J, Hougaard, D M, Jakovljević, M, Jett, M, Johnson, E O, Jones, I, Jovanovic, T, Qin, X-J, Karstoft, K-I, Kaufman, M L, Kessler, R C, Khan, A, Kimbrel, N A, King, A P, Koen, N, Kranzler, H R, Kremen, W S, Lawford, B R, Lebois, L A M, Lewis, C, Liberzon, I, Linnstaedt, S D, Logue, M W, Lori, A, Lugonja, B, Luykx, J J, Lyons, M J, Maples-Keller, J L, Marmar, C, Martin, N G, Maurer, D, Mavissakalian, M R, McFarlane, A, McGlinchey, R E, McLaughlin, K A, McLean, S A, Mehta, D, Mellor, R, Michopoulos, V, Milberg, W, Miller, M W, Morris, C P, Mors, O, Mortensen, P B, Nelson, E C, Nordentoft, M, Norman, S B, O'Donnell, M, Orcutt, H K, Panizzon, M S, Peters, E S, Peterson, A L, Peverill, M, Pietrzak, R H, Polusny, M A, Rice, J P, Risbrough, V B, Roberts, A L, Rothbaum, A O, Rothbaum, B O, Roy-Byrne, P, Ruggiero, K J, Rung, A, Rutten, B P F, Saccone, N L, Sanchez, S E, Schijven, D, Seedat, S, Seligowski, A V, Seng, J S, Sheerin, C M, Silove, D, Smith, A K, Smoller, J W, Sponheim, S R, Stein, D J, Stevens, J S, Teicher, M H, Thompson, W K, Trapido, E, Uddin, M, Ursano, R J, van den Heuvel, L L, Van Hooff, M, Vermetten, E, Vinkers, C, Voisey, J, Wang, Y, Wang, Z, Werge, T, Williams, M A, Williamson, D E, Winternitz, S, Wolf, C, Wolf, E J, Yehuda, R, Young, K A, Young, R M, Zhao, H, Zoellner, L A, Haas, M, Lasseter, H, Provost, A C, Salem, R M, Sebat, J, Shaffer, R A, Wu, T, Ripke, S, Daly, M J, Ressler, K J, Koenen, K C, Stein, M B & Nievergelt, C M 2021, ' Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2021.09.020
Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Academico-UPC
UPC-Institucional
Universidad Peruana de Ciencias Aplicadas
instacron:UPC
Biological Psychiatry
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Biological Psychiatry. Elsevier USA
Biological Psychiatry, 91(7), 626-636. ELSEVIER SCIENCE INC
Biological psychiatry, vol 91, iss 7

Funding Information: This work was supported by the National Institute of Mental Health / U.S. Army Medical Research and Development Command (Grant No. R01MH106595 [to CMN, IL, MBS, KJRe, and KCK], National Institutes of Health (Grant No. 5U01MH10953

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6907d48cedbb58a832cecbee3b996d
https://hdl.handle.net/10362/129670

Emotion regulation in undergraduate students with posttraumatic stress symptoms: A multimethod study

Autor: Susan M. Hannan, Holly K. Orcutt

Publikováno v: Psychological Trauma: Theory, Research, Practice, and Policy. 12:643-650

Objective: Existing literature suggests strong positive associations between posttraumatic stress disorder (PTSD) symptoms and emotion regulation difficulties; however, many of these findings are the result of monomethodological approaches (e.g., sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac7fae8c58d78b405204468765038be
https://doi.org/10.1037/tra0000577