Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Holly J. Kramer"'
Autor:
Alana C. Jones, Amit Patki, Vinodh Srinivasasainagendra, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Nicole D. Armstrong, Ninad S. Chaudhary, Bré Minniefield, Devin Absher, Donna K. Arnett, Leslie A. Lange, Ethan M. Lange, Bessie A. Young, Clarissa J. Diamantidis, Stephen S. Rich, Josyf C. Mychaleckyj, Jerome I. Rotter, Kent D. Taylor, Holly J. Kramer, Russell P. Tracy, Peter Durda, Silva Kasela, Tuuli Lappalinen, Yongmei Liu, W. Craig Johnson, David J. Van Den Berg, Nora Franceschini, Simin Liu, Charles P. Mouton, Parveen Bhatti, Steve Horvath, Eric A. Whitsel, Marguerite R. Irvin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease. Epigenetic modifications, such as DNA methylation at cytosine-phosphate-guanine (
Externí odkaz:
https://doaj.org/article/12deb3d0ae334de99921176e9c1f291a
Autor:
Alexander L. Bullen, Ronit Katz, Ujjala Kumar, Orlando M. Gutierrez, Mark J. Sarnak, Holly J. Kramer, Michael G. Shlipak, Joachim H. Ix, Suzanne E. Judd, Mary Cushman, Pranav S. Garimella
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Lipid accumulation product (LAP) and visceral adiposity index (VAI) are novel, non-imaging markers of visceral adiposity that are calculated by using body mass index (BMI), waist circumference (WC) and serum lipid concentrations.
Externí odkaz:
https://doaj.org/article/82e2adff25334d0ba0fcf50e74275fd7
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci
Autor:
Charles E. Breeze, Anna Batorsky, Mi Kyeong Lee, Mindy D. Szeto, Xiaoguang Xu, Daniel L. McCartney, Rong Jiang, Amit Patki, Holly J. Kramer, James M. Eales, Laura Raffield, Leslie Lange, Ethan Lange, Peter Durda, Yongmei Liu, Russ P. Tracy, David Van Den Berg, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group, Kathryn L. Evans, William E. Kraus, Svati Shah, Hermant K. Tiwari, Lifang Hou, Eric A. Whitsel, Xiao Jiang, Fadi J. Charchar, Andrea A. Baccarelli, Stephen S. Rich, Andrew P. Morris, Marguerite R. Irvin, Donna K. Arnett, Elizabeth R. Hauser, Jerome I. Rotter, Adolfo Correa, Caroline Hayward, Steve Horvath, Riccardo E. Marioni, Maciej Tomaszewski, Stephan Beck, Sonja I. Berndt, Stephanie J. London, Josyf C. Mychaleckyj, Nora Franceschini
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Abstract Background DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this a
Externí odkaz:
https://doaj.org/article/357ae5d7998e4adaaf16337fd7e2f26e
Autor:
Andrew P. Morris, Thu H. Le, Haojia Wu, Artur Akbarov, Peter J. van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J. Gaulton, Girish N. Nadkarni, Adan Valladares-Salgado, Niels Wacher-Rodarte, Josyf C. Mychaleckyj, Nicole D. Dueker, Xiuqing Guo, Yang Hai, Jeffrey Haessler, Yoichiro Kamatani, Adrienne M. Stilp, Gu Zhu, James P. Cook, Johan Ärnlöv, Susan H. Blanton, Martin H. de Borst, Erwin P. Bottinger, Thomas A. Buchanan, Sylvia Cechova, Fadi J. Charchar, Pei-Lun Chu, Jeffrey Damman, James Eales, Ali G. Gharavi, Vilmantas Giedraitis, Andrew C. Heath, Eli Ipp, Krzysztof Kiryluk, Holly J. Kramer, Michiaki Kubo, Anders Larsson, Cecilia M. Lindgren, Yingchang Lu, Pamela A. F. Madden, Grant W. Montgomery, George J. Papanicolaou, Leslie J. Raffel, Ralph L. Sacco, Elena Sanchez, Holger Stark, Johan Sundstrom, Kent D. Taylor, Anny H. Xiang, Aleksandra Zivkovic, Lars Lind, Erik Ingelsson, Nicholas G. Martin, John B. Whitfield, Jianwen Cai, Cathy C. Laurie, Yukinori Okada, Koichi Matsuda, Charles Kooperberg, Yii-Der Ida Chen, Tatjana Rundek, Stephen S. Rich, Ruth J. F. Loos, Esteban J. Parra, Miguel Cruz, Jerome I. Rotter, Harold Snieder, Maciej Tomaszewski, Benjamin D. Humphreys, Nora Franceschini
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Estimated glomerular filtration rate (eGFR) is a measure of kidney function used to define chronic kidney disease. Here, Morris et al. perform trans-ethnic genome-wide meta-analyses for eGFR in 312,468 individuals and identify novel loci and downstre
Externí odkaz:
https://doaj.org/article/b8a9cf68600449b683542f422dc012d2
Autor:
Caitlyn Vlasschaert, Cassianne Robinson-Cohen, Bryan Kestenbaum, Samuel A. Silver, Jian-Chun Chen, Elvis Akwo, Pavan K Bhatraju, Ming-Zhi Zhang, Shirong Cao, Ming Jiang, Yinqiu Wang, Aolei Niu, Edward Siew, Holly J Kramer, Anna Kottgen, Nora Franceschini, Bruce M. Psaty, Russell P. Tracy, Alvaro Alonso, Dan E. Arking, Josef Coresh, Christie M Ballantyne, Eric Boerwinkle, Morgan Grams, Matthew B. Lanktree, Michael J. Rauh, Raymond C. Harris, Alexander G. Bick
Publikováno v:
medRxiv
Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown and to date no genetic mechanisms for AKI have been established. Clonal hematopoiesis of indeterminate potential (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a861d4342548003bb591ac5b16a5bf0
https://doi.org/10.1101/2023.05.16.23290051
https://doi.org/10.1101/2023.05.16.23290051
Autor:
Nicolas, Krepostman, Holly J, Kramer
Publikováno v:
American Journal of Kidney Diseases. 80:561-563
Autor:
Yuni Choi, David R Jacobs, Holly J. Kramer, Gautam R. Shroff, Alexander R. Chang, Daniel A Duprez
BackgroundThe progression of chronic kidney disease (CKD) is higher in Black than in White Americans but studies have mainly focused on racial differences within advanced CKD. We evaluated CKD progression in Black and White participants over 20 years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883f1aac18fcea0d0a78dbfd603d1a47
https://doi.org/10.1101/2023.02.13.23285888
https://doi.org/10.1101/2023.02.13.23285888
Autor:
Holly J. Kramer, Bernard G. Jaar, Michael J. Choi, Paul M. Palevsky, Joseph A. Vassalotti, Michael V. Rocco
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 80(6)
Autor:
Yuni, Choi, David R, Jacobs, Holly J, Kramer, Gautam R, Shroff, Alexander R, Chang, Daniel A, Duprez
Publikováno v:
The American Journal of Medicine. 136:380-389.e10
There may be non-traditional pathways of chronic kidney disease (CKD) progression that are complementary to classical pathways. Therefore, we aimed to examine non-traditional risk factors for incident CKD and its progression.Generally healthy populat
Autor:
Siddharth Bhayani, Ramon Durazo-Arvizu, Kiang Liu, Martha L Daviglus, Erin Michos, Talar Markossian, Michael Rakotz, Greg Wozniak, Brent M Egan, Holly J Kramer
Publikováno v:
Circulation. 145
Introduction: Hypertension control is lower among women than men after age 65 years, but it is unknown whether age and sex disparities in hypertension control differ by race and ethnicity. We used data from the Multi-Ethnic Study of Atherosclerosis (