Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Holly J, Davis"'
Autor:
Holly J. Davis, Thomas R. Ward
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1120-1136 (2019)
Externí odkaz:
https://doaj.org/article/738ae7171d8044f3b61dd771245478d4
Publikováno v:
Chemcatchem
Through a rapid screening of Cp*Ir complexes based on a turn‐on type fluorescence readout, a [Cp*Ir(dipyrido[3,2‐a : 2’,3’‐c]phenazine)Cl]+ complex was found to catalyze the blue‐light promoted dehydrogenation of N‐heterocycles under ph
Publikováno v:
Angewandte Chemie (International Ed. in English)
Selective functionalization at the meta position of arenes remains a significant challenge. In this work, we demonstrate that a single anionic bipyridine ligand bearing a remote sulfonate group enables selective iridium‐catalyzed borylation of a ra
Publikováno v:
Synthesis. 50:793-802
Herein, we give a full account of the development of the palladium-catalysed cross-coupling of benzylammonium salts with boronic acids. A range of benzylamine-derived quaternary ammonium salts can be coupled with boronic acids under relatively mild
Autor:
Robert J. Phipps, Holly J. Davis
Publikováno v:
Chemical Science
This perspective examines the progress that has been made in using non-covalent interactions to control regioselectivity and site-selectivity in catalysis.
Asymmetric catalysis has been revolutionised by the realisation that attractive non-coval
Asymmetric catalysis has been revolutionised by the realisation that attractive non-coval
Publikováno v:
ChemCatChem. 12:4447-4447
Publikováno v:
Science (New York, N.Y.). 360(6387)
Basic heteroarenes are a ubiquitous feature of pharmaceuticals and bioactive molecules, and Minisci-type additions of radical nucleophiles are a leading method for their elaboration. Despite many Minisci-type protocols that result in the formation of
Autor:
Sophie H. Gilbert, Madeline E. Kavanagh, Andrew W. Munro, Kirsty J. McLean, Chris Abell, Holly J. Davis, Janine L. Gray, Anthony G. Coyne
Publikováno v:
Chemmedchem
The cyclo‐dipeptide substrates of the essential M. tuberculosis (Mtb) enzyme CYP121 were deconstructed into their component fragments and screened against the enzyme. A number of hits were identified, one of which exhibited an unexpected inhibitor
Publikováno v:
Journal of the American Chemical Society. 138(39)
The use of noncovalent interactions to direct transition-metal catalysis is a potentially powerful yet relatively underexplored strategy, with most investigations thus far focusing on using hydrogen bonds as the controlling element. We have developed
The search for new scaffolds to complement current HTS and fragment libraries is an active area of research. The development of novel strategies to synthesise compounds with 3D character in order to expand the diversity of a fragment library was expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48afc1dc5577652f6180d53685e1e345
https://www.repository.cam.ac.uk/handle/1810/256459
https://www.repository.cam.ac.uk/handle/1810/256459