Next Generation Sequencing Detects Premeiotic Errors in Human Oocytes

Autor: Harita Ghevaria, Sioban SenGupta, Roy Naja, Rabi Odia, Holly Exeter, Paul Serhal, Xavier Viñals Gonzalez, Xuhui Sun, Joy Delhanty

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 665, p 665 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 665
International Journal of Molecular Sciences

Autosomal aneuploidy is the leading cause of embryonic and foetal death in humans. This arises mainly from errors in meiosis I or II of oogenesis. A largely ignored source of error stems from germinal mosaicism, which leads to premeiotic aneuploidy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa4cd2f040b9ffd18699bbf5ed8dd2f
https://www.mdpi.com/1422-0067/23/2/665