Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Holly Dressler"'
Autor:
Zhen Pang, Nancy N. Wu, Holly Dressler, Sarah Favara, H. Greg Polites, Kyriakos D. Economides
Publikováno v:
SLAS Discovery. 19:232-241
Numerous assays have been developed to investigate the interactions between G-protein-coupled receptors (GPCRs) and their ligands since GPCRs are key therapeutic targets. Reporter-based assays using the cAMP response element (CRE) coupled with biolum
Autor:
Roberta Avallone, Zhen Pang, Michael J. Tocci, Pascual Ferrara, Holly Dressler, Xin Zhang, Tiziano Croci, H. Gregory Polites, Vaseem Palejwala, Nancy N. Wu
Publikováno v:
Molecular and Cellular Endocrinology. 325:18-25
The free fatty acid (FFA) receptor GPR40, expressed by pancreatic beta-cells, may be responsible for insulin release following beta(3) adrenoceptor (Adrb3) activation. To test this hypothesis, we first studied the effects of Adrb3 agonists SR58611A a
Autor:
Holly Dressler, Erica Schaffer, Vaseem Palejwala, Zhen Pang, Etienne Guillot, Daniel Weinstock, Chunpeng Fan, Xin Zhang, Souad Naimi, Jean Cavallo, Preeti Yamdagni, Michael J. Tocci, David C. Chain, Marie-Pierre Pruniaux, Kyriakos D. Economides, H. Greg Polites, Weiguang Zhao, Nancy N. Wu, Sarah Favara, Anne-Marie Galzin
Publikováno v:
Obesity (Silver Spring, Md.). 19(10)
Cannabinoid receptor CB1 is expressed abundantly in the brain and presumably in the peripheral tissues responsible for energy metabolism. It is unclear if the antiobesity effects of rimonabant, a CB1 antagonist, are mediated through the central or th
Autor:
Holly Dressler, Karl Herrup, Michael J. Comb, Haim Rosen, David Borsook, Steven E. Hyman, Michael Collard
Publikováno v:
Molecular Endocrinology. 6:1502-1512
A fusion gene containing 3 kilobases of human proenkephalin 5'-flanking sequences and 1 kilobase of human proenkephalin 3'-flanking sequence and the easily visualized histochemical marker, Escherichia coli beta-galactosidase, was used to study the fu