Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Holly D. Soares"'
Autor:
Yuk Yee Leung, Jon B. Toledo, Alexey Nefedov, Robi Polikar, Nandini Raghavan, Sharon X. Xie, Michael Farnum, Tim Schultz, Young Baek, Vivianna M. Van Deerlin, William T. Hu, David M. Holtzman, Anne M. Fagan, Richard J. Perrin, Murray Grossman, Holly D. Soares, Mitchel A. Kling, Matthew Mailman, Steven E. Arnold, Vaibhav A. Narayan, Virginia M‐Y. Lee, Leslie M. Shaw, David Baker, Gayle M. Wittenberg, John Q. Trojanowski, Li‐San Wang, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 3, Pp 339-348 (2015)
Abstract Introduction The dynamic range of cerebrospinal fluid (CSF) amyloid β (Aβ1–42) measurement does not parallel to cognitive changes in Alzheimer's disease (AD) and cognitively normal (CN) subjects across different studies. Therefore, ident
Externí odkaz:
https://doaj.org/article/42989bc2dc9e445d976979ab4e23062a
Publikováno v:
Annals of the New York Academy of Sciences. 747:172-182
Publikováno v:
Experimental Neurology. 167:1-14
Fos-lacZ and Jun-lacZ transgenic mice were used to assess the involvement of immediate-early genes in the axotomy-transcription coupling pathway triggered by sciatic nerve injury in neonates and adults. Nerve transection transiently induced Fos-lacZ
Publikováno v:
Journal of Neurotrauma. 12:1059-1067
Transplantation of fetal neural tissue has been demonstrated to prevent neuronal loss in a number of CNS injury models including spinal cord contusion. However, no studies have examined the neuroprotective role of fetal transplants in models of traum
Autor:
Tom Curran, Gabriella D'Arcangelo, James I. Morgan, Shu-Cheng Chen, Graham G. Miao, Holly D. Soares
Publikováno v:
Nature. 374:719-723
The autosomal recessive mouse mutation reeler leads to impaired motor coordination, tremors and ataxia. Neurons in affected mice fail to reach their correct locations in the developing brain, disrupting the organization of the cerebellar and cerebral
Autor:
Holly D, Soares, William Z, Potter, Eve, Pickering, Max, Kuhn, Frederick W, Immermann, David M, Shera, Mats, Ferm, Robert A, Dean, Adam J, Simon, Frank, Swenson, Judith A, Siuciak, June, Kaplow, Madhav, Thambisetty, Panayiotis, Zagouras, Walter J, Koroshetz, Hong I, Wan, John Q, Trojanowski, Leslie M, Shaw, Dick, Drost
Publikováno v:
Archives of neurology. 69(10)
Background A blood-based test that could be used as a screen for Alzheimer disease (AD) may enable early intervention and better access to treatment. Objective To apply a multiplex immunoassay panel to identify plasma biomarkers of AD using plasma sa
Autor:
John A. Connor, Tom Curran, Colin L. Stewart, Douglas Forrest, Lily Ng, Daniel C. Luk, Michisuke Yuzaki, Morgan Sheng, James I. Morgan, Holly D. Soares
Publikováno v:
Neuron. 13:325-338
In vitro studies have suggested that the NMDA receptor consists of an essential subunit, NR1, and various modulatory NR2 subunits. To test this hypothesis directly in vivo, we generated mice carrying a disrupted NR I allele. NMDA-inducible increases
Autor:
Holly D, Soares, Yu, Chen, Marwin, Sabbagh, Alex, Roher, Alex, Rohrer, Elisabeth, Schrijvers, Monique, Breteler
Publikováno v:
Annals of the New York Academy of Sciences. 1180
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder with incidence expected to increase four-fold over the next decade. Extensive research efforts are focused upon identifying new treatments, and early diagnosis is considered key to
Autor:
Holly D, Soares, Stephen A, Williams, Peter J, Snyder, Feng, Gao, Tom, Stiger, Christian, Rohlff, Athula, Herath, Trey, Sunderland, Karen, Putnam, W Frost, White
Publikováno v:
International review of neurobiology. 61
Autor:
Marcia Pecot, Amady Soumare, Adalynn E. Harris, James I. Morgan, Anwar Osborne, Holly D. Soares
Publikováno v:
Molecular and cellular neurosciences. 16(5)
To identify genes involved in axon regeneration, differential screening was applied to RNA isolated from spinal cord of mice subjected to sciatic nerve transection or crush injury. A 4-kb transcript, termed nna1, was identified that was rapidly induc