Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Holly Colognato"'
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/f0924efbe7b64455877974cd17058937
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Multiple Sclerosis (MS) is a chronic disease characterized by immune-mediated destruction of myelinating oligodendroglia in the central nervous system. Loss of myelin leads to neurological dysfunction and, if myelin repair fails, neurodegeneration of
Externí odkaz:
https://doaj.org/article/5e5f10eca02f4a919e5f4c76ee02099d
Autor:
Mohanlall Narine, Holly Colognato
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Once believed to be part of the nervenkitt or “nerve glue” network in the central nervous system (CNS), oligodendroglial cells now have established roles in key neurological functions such as myelination, neuroprotection, and motor learning. More
Externí odkaz:
https://doaj.org/article/f8c673c2a5454e478f5f6ab39fa1df11
Autor:
Andrea J. Arreguin, Holly Colognato
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Laminin α2 gene (LAMA2)-related Congenital Muscular Dystrophy (CMD) was distinguished by a defining central nervous system (CNS) abnormality—aberrant white matter signals by MRI—when first described in the 1990s. In the past 25 years, researcher
Externí odkaz:
https://doaj.org/article/055c913ecb7f49f0a9e950bd880c8b1e
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 984-999 (2018)
Summary: The regulatory mechanisms that control neural stem cell (NSC) activation in the adult ventricular-subventricular zone (V-SVZ) stem cell niche have been the focus of intense investigation, yet how the niche first develops and organizes is poo
Externí odkaz:
https://doaj.org/article/1fc2d9f31daf4598aea96ee27f7ee644
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background In Duchenne muscular dystrophy (DMD), the loss of the dystrophin component of the dystrophin-glycoprotein complex (DGC) compromises plasma membrane integrity in skeletal muscle, resulting in extensive muscle degeneration. In addit
Externí odkaz:
https://doaj.org/article/b7e455f971984d548029bb01eec4016d
Autor:
Saul S Siller, Himanshu Sharma, Shuai Li, June Yang, Yong Zhang, Michael J Holtzman, Wipawee Winuthayanon, Holly Colognato, Bernadette C Holdener, Feng-Qian Li, Ken-Ichi Takemaru
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007128 (2017)
Multiciliated cells of the airways, brain ventricles, and female reproductive tract provide the motive force for mucociliary clearance, cerebrospinal fluid circulation, and ovum transport. Despite their clear importance to human biology and health, t
Externí odkaz:
https://doaj.org/article/9320a9d52c3341d98b08f60583384dcf
Autor:
Karine Loulier, Justin D Lathia, Veronique Marthiens, Jenne Relucio, Mohamed R Mughal, Sung-Chun Tang, Turhan Coksaygan, Peter E Hall, Srinivasulu Chigurupati, Bruce Patton, Holly Colognato, Mahendra S Rao, Mark P Mattson, Tarik F Haydar, Charles Ffrench-Constant
Publikováno v:
PLoS Biology, Vol 7, Iss 8, p e1000176 (2009)
During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zone (VZ) lining the cerebral ventricles. They exhibit apical and basal processes that contact the ventricular surface and the pial bas
Externí odkaz:
https://doaj.org/article/5f881e0fdd104c3eb873539ae22afc01
Publikováno v:
Methods in cell biology. 168
Healthy myelin is essential for proper brain function. When the myelin sheath is damaged, fast saltatory impulse conduction is lost and neuronal axons become vulnerable to degeneration. Thus, regeneration of the myelin sheath by encouraging oligodend
Autor:
Akiko Nishiyama, Holly Colognato
Publikováno v:
Neuroscience letters. 730