Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Holly A. Williams"'
Autor:
Felipe Paredes, Holly C. Williams, Xuesong Liu, Claire Holden, Bethany Bogan, Yu Wang, Kathryn M. Crotty, Samantha M. Yeligar, Alvaro A. Elorza, Zhiyong Lin, Amir Rezvan, Alejandra San Martin
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103203- (2024)
Vascular smooth muscle cells (VSMCs), known for their remarkable lifelong phenotypic plasticity, play a pivotal role in vascular pathologies through their ability to transition between different phenotypes. Our group discovered that the deficiency of
Externí odkaz:
https://doaj.org/article/57f4954af63347f2a85440ad693065b8
Autor:
Bethany J. Bogan, Holly C. Williams, Claire M. Holden, Vraj Patel, Giji Joseph, Christopher Fierro, Hugo Sepulveda, W. Robert Taylor, Amir Rezvan, Alejandra San Martin
Publikováno v:
Cells, Vol 13, Iss 8, p 658 (2024)
Vascular smooth muscle cells (VSMCs), in their contractile and differentiated state, are fundamental for maintaining vascular function. Upon exposure to cholesterol (CHO), VSMCs undergo dedifferentiation, adopting characteristics of foam cells—lipi
Externí odkaz:
https://doaj.org/article/4732a12e4c74475f9b2047336dfa930c
Autor:
Alejandra Valdivia, Charity Duran, Mingyoung Lee, Holly C. Williams, Moo-Yeol Lee, Alejandra San Martin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell migration is essential for many biological and pathological processes. Establishing cell polarity with a trailing edge and forming a single lamellipodium at the leading edge of the cell is crucial for efficient directional cell migration and is
Externí odkaz:
https://doaj.org/article/942d523162f94472b0770f1c0f544b37
Autor:
Felipe Paredes, Holly C. Williams, Izabela Suster, Macarena Tejos, Roberto Fuentealba, Bethany Bogan, Claire M. Holden, Alejandra San Martin
Publikováno v:
Free Radical Biology and Medicine. 195:283-297
The polymerase delta interacting protein 2 (Poldip2) is a nuclear-encoded mitochondrial protein required for oxidative metabolism. Under hypoxia, Poldip2 expression is repressed by an unknown mechanism. Therefore, low levels of Poldip2 are required t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ae34dae22b06295438641a4c425eaa
https://doi.org/10.1016/j.freeradbiomed.2022.12.098
https://doi.org/10.1016/j.freeradbiomed.2022.12.098
Autor:
Program on Forced Migration and Health at the Mailman School of Public Health of Columbia University, National Research Council, Committee on Population, Roundtable on the Demography of Forced Migration, Holly A. Williams, Peter B. Bloland
Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migratio
Autor:
Alejandra Valdivia, Hanjoong Jo, Holly C. Williams, Elena V Dolmatova, Steven J. Forrester, Marina S. Hernandes, Keke Wang, Giji Joseph, Hongyan Qu, Kathy K. Griendling, Bernard Lassègue, A. Kowalczyk, Ziwei Ou, Sandeep Kumar
Publikováno v:
Cardiovasc Res
Aims Sepsis-induced lung injury is associated with significant morbidity and mortality. Previously, we showed that heterozygous deletion of polymerase δ-interacting protein 2 (Poldip2) was protective against sepsis-induced lung injury. Since endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0a109eb648943fef26c87f34f5699c
https://doi.org/10.1093/cvr/cvab295
https://doi.org/10.1093/cvr/cvab295
Publikováno v:
Circ Res
Rationale: The mitochondrial Poldip2 (protein polymerase interacting protein 2) is required for the activity of the tricarboxylic acid cycle. As a consequence, Poldip2 deficiency induces metabolic reprograming with repressed mitochondrial respiration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cb9b177c4ce031e6aced7bb4397201
https://doi.org/10.1161/circresaha.119.315932
https://doi.org/10.1161/circresaha.119.315932
Autor:
Holly Ann Williams, Joanna Gaines, Molly Patrick, David Berendes, David Fitter, Thomas Handzel
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142778 (2015)
The international response to Haiti's ongoing cholera outbreak has been multifaceted, including health education efforts by community health workers and the distribution of free water treatment products. Artibonite Department was the first region aff
Externí odkaz:
https://doaj.org/article/13323a9e8dc244e7b7b793c9c31ba387
Autor:
Abel Martin-Garrido, Holly C Williams, Minyoung Lee, Bonnie Seidel-Rogol, Xinpei Ci, Jin-Tang Dong, Bernard Lassègue, Alejandra San Martín, Kathy K Griendling
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79657 (2013)
In adult tissue, vascular smooth muscle cells (VSMCs) exist in a differentiated phenotype, which is defined by the expression of contractile proteins and lack of proliferation. After vascular injury, VSMC adopt a synthetic phenotype associated with p
Externí odkaz:
https://doaj.org/article/fe7e3d05cfa5443490afb86850d03f2b
Publikováno v:
Cancer Lett
The ability of tumor cells to adapt to changes in oxygen tension is essential for tumor development. Low oxygen concentration influences cellular metabolism and, thus, affects proliferation, migration, and invasion. A focal point of the cell's adapta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbcd7b396f6a9a13e8bf28ee6b54dad
https://pubmed.ncbi.nlm.nih.gov/33444690
https://pubmed.ncbi.nlm.nih.gov/33444690