Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Holly A. Richendrfer"'
Autor:
Adam Chodobski, Gregory D. Jay, Tannin A. Schmidt, Nathalie Strazielle, Marissa Bennett, Holly A. Richendrfer, Hyung Jin Lee, Emma Morales Cestero, Joanna Szmydynger-Chodobska, Jean-François Ghersi-Egea, Steven W. Threlkeld, Andrea T. Chin
Publikováno v:
Journal of Neurotrauma
Neuroinflammation and dysfunction of the blood–brain barrier (BBB) are two prominent mechanisms of secondary injury in neurotrauma. It has been suggested that Toll-like receptors (TLRs) play important roles in initiating and propagating neuroinflam
Autor:
Holly A. Richendrfer, Gregory D. Jay
Publikováno v:
Crit Care Clin
Proteoglycan 4 (or lubricin), a mucin-like glycoprotein, was originally classified as a lubricating substance within diarthrodial joints. More recently, lubricin has been found in other tissues and has been implicated in 2 inflammatory pathways withi
Autor:
Khaled A. Elsaid, Gregory D. Jay, Ralph Cabezas, Holly A. Richendrfer, Tannin A. Schmidt, Mitchell M. Levy, Ling Zhang
Publikováno v:
Critical Care Explorations
Supplemental Digital Content is available in the text.
Objectives: Sepsis is a leading cause of death in the United States. Putative targets to prevent systemic inflammatory response syndrome include antagonism of toll-like receptors 2 and 4 and
Objectives: Sepsis is a leading cause of death in the United States. Putative targets to prevent systemic inflammatory response syndrome include antagonism of toll-like receptors 2 and 4 and
Autor:
Holly A. Richendrfer, Robbert Creton
Publikováno v:
Neurotoxicology and teratology. 69
Antidepressants are used by a substantial number of women in their childbearing years. Treatment may continue during pregnancy, since untreated depression poses a risk to the mother and child. However, many antidepressants readily pass through the pl
Autor:
Elana Nack, Holly A. Richendrfer, Jennifer M. Swann, Lindsay Dawson, Tim Garelick, Jack Whylings
Publikováno v:
Hormones and Behavior. 64:421-429
The magnocellular division of the medial preoptic area (MPN mag) integrates pheromonal and hormonal signals to play a critical role in the expression of male typical sex behavior. The MPN mag contains two morphologically distinct neuronal populations
Autor:
Colby Davis, Holly A. Richendrfer, Rachel A. Altura, Kevin Nguyen, Bradley DeNardo, Chanika Phornphutkul, Robbert Creton, Cynthia L. Jackson, Michael P. Holloway
Publikováno v:
NPJ Genomic Medicine
Targeted next-generation sequencing (NGS) identified a novel loss of function mutation in GARS, a gene linked to Charcot–Marie–Tooth disease (CMT), in a paediatric acute lymphoblastic leukaemia patient with severe chemotherapy-induced peripheral
Publikováno v:
Neurotoxicology and Teratology. 34:458-465
Neurobehavioral disorders such as anxiety, autism, and attention deficit hyperactivity disorders are typically influenced by genetic and environmental factors. Although several genetic risk factors have been identified in recent years, little is know
Publikováno v:
Behavioural Brain Research. 228:99-106
Zebrafish larvae are ideally suited for high-throughput analyses of vertebrate behavior. The larvae can be examined in multiwell plates and display a range of behaviors during early development. Previous studies have shown that zebrafish larvae displ
Autor:
Robbert Creton, Holly A. Richendrfer
Publikováno v:
Neurotoxicology. 49
Organophosphates, a type of neurotoxicant pesticide, are used globally for the treatment of pests on croplands and are therefore found in a large number of conventional foods. These pesticides are harmful and potentially deadly if ingested or inhaled
Autor:
Holly A. Richendrfer, Mary K. LoPiccolo, Danielle E. Clift, Ruth M. Colwill, Mrinal Kapoor, Emily A. Passarelli, Robbert Creton, Robert J. Thorn
Publikováno v:
Behavioural brain research. 282
Cyclosporine, a calcineurin inhibitor, is successfully used as an immunosuppressant in transplant medicine. However, the use of this pharmaceutical during pregnancy is concerning, since calcineurin is thought to play a role in neural development. The